Alper-JCCC Molecular Epidemiology Symposium:

Advances of Gene-Environmental Interaction and Lung and Other Smoking-related Cancers

8:00 AM – 6:00 PM, April 14, 2007

GondaBuilding, First Floor Conference Room

The symposium is sponsored by the Ann Fitzpatrick Alper Program in Environmental Genomics and the UCLA Jonsson Comprehensive Cancer Center (JCCC), the symposium is also co-sponsored by the UCLACenter for Occupational and Environmental Health (COEH), UCLA Lung SPORE, and the UCLA Molecular Epidemiology Training and Research Program.

7:00-7:50Breakfast

7:50-8:20Introduction: Dr. Roshan Bastani, Dr. Zuo-Feng Zhang, Dr. Jeanette Papp and Dr. Stephen Dubinett

Session One: Keynote Lectures

8:20-9:20

Advances of Genetic Susceptibility of Lung and Head and Neck Cancer

Dr. Paolo Boffetta

Coordinator, Genetics and Epidemiology Cluster

International Agency for Research on Cancer

150 cours Albert Thomas

69008 LyonFrance

Tel +33-472738554

Fax +33-472738320

"Dr. Paolo Boffetta" <>

9:20-10:20

NAT2, GSTM1, occupational and tobacco exposures, and bladder cancer: historical perspective and lessons learned about studying gene-environment interactions

Nathaniel Rothman, M.D., M.P.H., M.H.S.
Senior Investigator
Division of Cancer Epidemiology and Genetics

NationalCancerInstitute
ExecutivePlaza South, Room 8116
6120 Executive Boulevard
MSC 7242
Bethesda, Maryland20892-7335

Phone: 301-496-9093
Fax: 301-402-1819
E-mail:

10:20-10:30Tea Break

Session 2: Gene-Environmental Interaction on Risk, Progression and Chemoprevention of Lung and Smoking-related Cancers

10:30-11:10

Tobacco Carcinogenesis: a Pathway-based Approach

Xifeng Wu, MD, PhD

Professor of Epidemiology

Department of Epidemiology - Box 1340

The University of TexasM.D.AndersonCancerCenter

1155 Pressler Blvd

Houston, TX 77030

CPB 4.3209

Telephone: (713) 745-2485

Fax: (713) 792-4657

E-mail:

11:10-11:50

Molecular Therapeutics and Chemoprevention of Lung Cancer

Ruiwen Zhang, MD, PhD, DABT

Professor, Clinical Pharmacology, Pharmacology and Toxicology

Director, Cancer Pharmacology Laboratory

University of Alabama at Birmingham

VH 113, Box 600

1670 University Blvd.

Birmingham, AL35294-0019

(205) 934-8558 (Phone)

(205) 975-9330 (FAX)

11:50-12:30

Whole genome association study of lung cancer

Jianfeng Xu, M.D. Dr.PH.

Professor of Public Health and Cancer Biology

Director, Program for Genetic and Molecular Epidemiology of Cancer

Associate Director, Center for Human Genomics

WakeForestUniversitySchool of Medicine

Medical Center Blvd

Winston-Salem, NC27157

Tel: (336) 713-7500

Fax: (336) 713-7566

Email:

12:30-1:30 Lunch

1:30-2:10

Gene-Environment Interaction on Lung Cancer Progression and Survival

Ping Yang, MD, PhD

Professor

MayoClinicCollege of Medicine

Email:

2:10-2:50

Inflammation and Lung Cancer Risk

Qiuyin Cai, MD, PhD

Assistant Professor

VanderbiltEpidemiologyCenter

Institute of Medicine and Public Health

VanderbiltUniversityMedicalCenter

PRB 636, 2220 Pierce Avenue

Nashville, TN 37232-6838

Phone: 615-936-1351

Fax: 615-936-1790

Email:

2:50-3:30

Molecular Epidemiology Study of Indoor Air Pollution and Lung Cancer.

Qing Lan, M.D., M.P.H., Ph.D.

Investigator

Occupational & Environmental Epidemiology Branch

Division of Cancer Epidemiology & Genetics

National Cancer Institute

6120 Executive Blvd. EPS Room 8109

Bethesda, Maryland20892-7238

Telephone: (301) 435-4706

Fax (301) 402-1819

E-mail:

3:30-3:40 Tea Break

3:40-4:00

UCLA Lung Cancer Chemoprevention Trial, An Update

Jenny Mao, MD

Associate Professor

UCLASchool of Medicine

Med-Pul & Critical Care

Box 951690, 37-131 CHS

Los Angeles, CA 90095-1690

Phone: 310-825-3100

Fax: 310-206-8622

Email:

4:00-4:20

Molecular Epidemiology of Lung Cancer in Chinese Population

Hongbing Shen, MD, PhD

Professor of Epidemiology

Dean, School of Public Health

NanjingMedicalUniversity

Nanjing 210029, Jiangsu

People¡¯s Republic of China

Tel:(86)25-8686-2756

Fax:(86)25-8652-7613

Email:

4:20-4:40

XRCC1/LIG1 polymorphisms, Indoor Air pollution risk of lung cancer in Taiyuan, China

Lina Mu, MD, PhD

Associate Professor

Department of Epidemiology

FudanUniversitySchool of Public Health

Shanghai 200032

People’s Republic of China

Email:

Li Liu, MD

Director, Chronic Disease Prevention and Control

TaiyuanCenter for Chronic Disease Prevention and Control

Taiyuan CDC, China

Tel: 0351-7227554

4:40-5:00

Passive Smoking and Head and Neck Cancer among Non-Smokers

Amy Lee, PhD

Gene Environment Epidemiology Group
International Agency for Research on Cancer
150 Cours Albert-Thomas
69008Lyon
France
email: <>

5:00-5:20

NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung cancer

Chun (Rebecca) Chao, PhD

Department of Research and Evaluation

Kaiser Permanente Southern California

100 S. Los Robles, Suite 201

Pasadena, CA91101

Tel: 626-564-3797

Fax: 626-564-3409

Email:

5:20-5:40

Lung Cancer Susceptibility(LCS) Study Survival Outcomes:An Update

Rebecca Suk Heist, MD MPH

Instructor in Medicine, HarvardMedicalSchool

Massachusetts GeneralHospitalCancerCenter

Yawkey 7B

55 Fruit Street

BostonMA02114

phone: 617 724 4000

fax: 617 726 0453

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