Joint Meeting of the Belgian and British Biophysical Societies

Palace of Academies, Brussels, 22 – 23 February 2018

Thursday February 22nd

Protein Folding, Misfolding, Assembly and Design

10:00-10:30 Sheena Radford(Astbury Centre for Structural Molecular Biology, University of Leeds)

“Exploiting protein-protein interactions to ameliorate amyloid disease”

10:30-11:00 ArnoutVoet(Laboratory of biomolecular modelling and design, KUniversityLeuven)

“RE3Volutionary Design of Symmetric Protein Building Blocks”

11:00-11:20 Student/Postdoc talk

Coffee break

11:50-12:20 Sergi Garcia Manyes (Department of Physics & Randall Centre for Cell and Molecular Biophysics, King’s College London’)

"Linking mechanochemistry with protein folding with single bond resolution”

12:20-12:50 Kenneth Verstraete (VIB-UGentCenter for Inflammation Research, University of Gent)

"Molecular and evolutionary insights into the structure and mechanism of the giant citrate-cleavage enzyme”

Lunch and special ERC session

13:30-14:20InoAgrafioti(coordinator of the ERC panel LS1 Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics).

“How to apply for an ERC grant”

Protein Folding, Misfolding, Assembly and Design (continued)

14:20-14:50 Justin Benesch (Department of Chemistry, University of Oxford)

“Biophysics of selective protein self- and co-assembly”

14:50-15:20 Mireille Dumoulin (Centre for Protein Engineering, University of Liège)

“Use of structural probes to study protein misfolding and aggregation”

15:20-15:40 Student/Postdoc talk

Coffee break

16:10-16:40Paula Booth (Department of Chemistry, King's College London)

“Folding alpha helical membrane proteins”

16:40-17:10 Jan Steyaert (VIB-VUB Center for Structural Biology, VUniversityBrussels)

“Title pending”

17:10-17:30 Student/Postdoc talk

Friday March 23rd

Proteins and Membranes

10:00-10:30 Jean-Marie Ruysschaert (Laboratory for the Structure and Function of Biological Membranes, UniversitéLibre de Bruxelles, Brussels)

“New activators of Toll-like Receptors:from self-assembled lipids to amyloids”

10:30-11:00 Frank Sobott ((Astbury Centre for Structural Molecular Biology, University of Leeds)

Dynamic protein structure: from protein disorder to membrane pores

11:00-11:20 Student/Postdoc talk

Coffee break

11:50-12:20 Anthony Watts (Department of Biochemistry, University of Oxford)

“Exploiting multiple spectroscopies to study GPCR siganlling”

12:20-13:40 Student/Postdoc talk

Protein Folding, Misfolding, Assembly and Design (ending)

12:40-13:10 Tuomas Knowles (Department of Chemistry, University of Cambridge)

Probing proteins in small volumes"

Lunch

Imaging

14:00-14:30 Johan Hofkens (Department of Chemistry, KUiniversityLeuven)

14:30-15:00 Corinne Smith (School of Life Sciences, University of Warwick)

Resolving clathrin cage interactions using high resolution cryoEM

15:00-15:20 Student/Postdoc talk

Coffee break

15:50-16:20 RouslanEfremov (VIB-VUB Center for Structural Biology VUniversityBrussels)

Structure and mechanism of ryanodine receptor resolved by single particle cryo-EM

16:20-16:50 David Alsteens (NanoBioPhysics of cells, UniversityCLouvain)

High-Resolution Imaging and Nanomechanical Mapping of Receptors on Living Cells

16:50-17:10 Student/Postdoc talk