NSF SBIR Opportunities
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(Others beside the highlighted areas below include advanced manufacturing and nanotechnology, advanced materials and instrumentation, chemical and environmental technologies, electronic hardware, robotics, and wireless technologies, information technologies, internet of things, semiconductors and photonic devices and materials, and other topics.

Biological Technologies: Biosensors; Life Sciences Research Tools; Bioinstrumentation; Synthetic Biology & Metabolic Engineering; Fermentation & Cell Culture Technologies; Computational Biology & Bioinformatics; Advanced Biomanufacturing (New, focus on tissue-engineered regenerative medicine therapies); Advanced Technologies for Functional Genomics in Organismal Systems; and Tissue Engineering & Regenerative Medicine.

Biomedical Technologies:The Biomedical Technologies subtopics aim to support the early stage development of novel products, processes, or services that will enable the delivery of high-quality, economically-efficient healthcare in the U.S. as well as globally.The BM subtopics are not aimed at supporting or conducting clinical trials, clinical efficacy or safety studies, the development pre-clinical or clinical-stage drug candidates or medical devices, or work performed primarily for regulatory purposes.Limited studies with human subjects may be acceptable to the extent that they are performed in support of feasibility, proof-of-concept studies of early-stage technologies.

Topics: Pharmaceutical Manufacturing; Materials for Biomedical Applications; Biomedical Engineering; Noninvasive Imaging of Brain Function; Medical Imaging Technologies; Diagnostic Assays & Platforms; Drug Delivery

Smart Health: The need for a significant healthcare transformation has been recognized by numerous organizations, including the President's Council of Advisors on Science and Technology (PCAST), National Research Council (NRC), Institute of Medicine (IOM), Computing Community Consortium (CCC), the National Academy of Engineering and the Office of the National Coordinator for Health Information Technology (ONC). The Smart Health subtopics aim to support the early stage development of novel devices, components, systems, algorithms, networks, applications, or services that will enable the much needed transformation of healthcare from reactive, hospital-centered, and indemnity-based to proactive, person-centered, preventive, and cost-efficient.The SH subtopics are not aimed at supporting clinical trials, the clinical validation of information technologies, or medical devices or studies performed primarily for regulatory purposes.Limited studies with human subjects may be acceptable to the extent that they are performed in support of feasibility, proof-of-concept studies of early-stage technologies.

Topics: Business Modes for User-Centered Healthcare, Digital Health Information Infrastructure, From Data to Decisions, Interoperability of Health Record Systems, Medical Sensors, Devices & Robotics.

Educational Technologies and Applications: Pre K-12 Education; Global, Distance, & Higher Education; Simulations & Gaming Technologies; Entrepreneurial, Informal, and Maker Education; Information, Computer Science, & Engineering