Table SI 4. Germline mouse mutations caused by viral retrotransposon insertion.

Locus / Mutant mouse name / Strain of origin / Reference
Early transposon (ETn)
Adcybrl / barreless / ICR / 1
Cacng2stg / stargazer / A/J / 2
Cacng2stg3J / stargazer-3J / BALB/cJ / 3
Clc1adr / myotonia / A2G / 4
Tnfrfs6lpr / lymphoproliferative response / MRL/MpJ / 5
EdarDl-slk / sleek / STOCK Rb(8.12)5Bnr Tyrp1bm / 6
Fbxw4Dac / dactylaplasia / SM/Ckc / 7
Fbxw4Dac-2J / dactylaplasia-2J / MRL/MpJ / 7
Fignfi / fidget / unknown/mixed / 8
Foxn1nu-BC / nude-British Columbia / STOCK Spna1sph-2Bc / 9
Gli3pdn / extra-toes / Jcl:ICR / 10
Hk1dea / downeast anemia / A/J / 11
H2Q8 / MHC expression variant / strain variant / 12
Mip / major intrinsic protein of eye lens fiber / strain variant / 13
MipCat-Fr / Dominant cataract (Fraser) / A/J
Mutedmu / muted / STOCK t / 14
Lepob2J / obese / SM/Ckc-Fbxw4Dac / 15
Tyrc-BC3 / albino-British Columbia 3 / STOCK Spna1sph-2Bc / 9
Intracisternal A-type Particle (IAP)
Avy / viable yellow / C3H/HeJ / 16
Ahvy / hypervariable yellow / C3H/HeSnJ / 17
Aiapy / agouti IAP yellow / B6C3F1/J / 18
Atrnmg / mahogany / C3H x Swiss stock / 19
Atrnmg-L / mahogany-Leicester / C3H/HeJ / 19
AxinFu / fused / unspecified / 20
AxinKb / knobbly / unspecified / 20
Dab1scm / scrambler / Dc/Le / 21
Eya1bor / branchio otorenal syndrome / C3H/HeJ / 22
GusMps2J / mucopolysaccharidosis-3J / C3H/HeOuJ / 23
Hps1ep / pale ear / C3HeB/FeJ / 24
Hps3coa6J / cocoa-6J / C3H/HeJ / 25
Lamb3Iap / Herlitz junctional epidermolysis bullosa / C3H / 26
Pitp1bvb / vibrator / DBA/2J / 27
RelnAlb2J / reelin-Albany-2 / C3H/HeJ / 28
Spna1sph-Dem / spherocytosis-Demant / CcS3/Dem / 29
Tyrc-1R / albino-1R / (101/Rl x C3H/Rl)F1 / 30
Usp14ax / ataxia / CBA/J / 31
Murine leukemia virus (MLV)
Abcb1a / multiple drug resistance-3 / strain variant / 32
AifHq / harlequin / CF1 / 33
Myo5ad / dilute / fancy mice / 34
hr / hairless / unknown / 35
Pde6brd1 / retinal-degeneration 1 / fancy mice / 36
Virus-like 30 (VL30)
a / non-agouti / fancy mice / 37

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21Sheldon, M. et al. Scrambler and yotari disrupt the disabled gene and produce a reeler- like phenotype in mice. Nature389, 730-733 (1997).

22Johnson, K. R. et al. Inner ear and kidney anomalies caused by IAP insertion in an intron of the Eya1 gene in a mouse model of BOR syndrome. Hum Mol Genet8, 645-653 (2000).

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