Course Title / Human Physiology I
Course Code / PT112
Course Credit / Lecture: 06
Practical: 02
Tutorial: 0
Total: 08
Course Learning Outcomes
  1. To understand the principles of human physiology for the various systems of the human body at a microscopic and macroscopic level.
  2. To able to understand the functional physiology of cell, blood, neuromuscular, cardiovascular and pulmonary systems,
  3. To relate the concept of human physiology in physiotherapy application including exercises physiology.

Detailed Syllabus
Sr. No. / Contents / Hours Allotted
SECTION – I
1. / General Physiology
Cell Structure and organelle. / 2 / 0
General Principles of Biophysics. / 4 / 0
Body Fluid compartments. / 2 / 0
2. / Blood
Composition of blood, Plasma, protein formation and their function / 4 / 2
Structure, formation and function of R.B.C. / 2 / 6
Structure formation and functions W.B.C. and Platelets. / 2 / 6
Coagulation and its defects of bleeding, clotting time. / 2 / 4
Blood group and their significance, Rh. Factor / 2 / 4
Reticulo Endothelial system, structure and functions of spleen, Jaundice. / 2 / 0
Hemoglobin and E.S.R. / 2 / 6
3. / Nerve physiology
Structure of neuron, membrane potential and generation of action potential. / 4 / 4
Nerve impulse conduction, salutatory conduction. / 3 / 0
Nerve muscular junction and drugs acting on it-Myasthenia. / 2 / 0
Degeneration and regeneration in peripheral nerves- Wallerian degeneration of electro tonus and flaggers law. / 2 / 0
4. / Muscle physiology
Type of muscles and their gross structure, stimulus chronaxie, strength duration curve. / 3 / 4
Structure of Sarcomere- basis of muscles contraction, Starlings law, changes during muscle contraction. / 4 / 0
Electrical- Biphasic and monophasic action potentials. / 3 / 0
Chemical, Thermal and Physical changes, isometric and isotonic contraction. / 4 / 0
Motor units and its properties. Clonus tetanus, all or none law, beneficial effect. / 3 / 0
Nature of voluntary contraction, fatigue. / 2 / 0
SECTION – II
5. / Respiratory System
Mechanism of respiration, intra-pleural and intra pulmonary pressure. / 8 / 0
Lung volumes and capacities. / 4 / `10
O2 and CO2 carriage and their exchange in tissues and lungs. / 8 / 2
Nervous, chemical regulation of respiration- Respiratory Centers. / 6 / 0
Respiratory states-anoxia, asphyxia, Cyanosis, Acclimatization. / 4 / 0
6. / Cardiovascular System
Structure, Properties of heart muscle and nerve supply of heart, / 4 / 0
Structure and function of arteries, arterioles, capillaries and veins. / 4 / 0
Cardiac cycle and heart sounds. / 2 / 8
Cardiac output measurement, factors affecting to it. / 4 / 4
Blood pressure, its regulations and physiological variations. / 2 / 6
Peripheral resistance, factors controlling role B.P. / 4 / 0
Hemorrhage. / 2 / 0
Changes in muscular exercise. / 2 / 6
Instructional Method and Pedagogy:
  1. Teaching and training sessions will be carried out through active learning. Active participation and contribution in group discussion and seminars are mandatory for students
  2. Lectures to be conducted with the help of black board and/or audio-visual aids that includes multi-media projector, OHP, etc.
  3. Assignments based on course content will be given to the students at the end of each unit/topic and will be evaluated at regular interval
  4. The course includes a laboratory where the students have an opportunity to build and appreciation for the concepts being taught in lectures

Text Books
  1. Course in Medical Physiology—Vol-I and II-by Dr. Chaudhari
  2. Understanding Medical Physiology: 4th edition. Dr. Bijlani. Jaypee Publication
  3. Essential of Medical Physiology: 4th edition. Sembulingam. Jaypee Publication

Reference Books
  1. Guyton and Hall Textbook of Medical Physiology: 12th Edition. Hall JE. Saunders publication 2010
  2. Physiology: Prep Manual for undergraduates: 4th edition. Dr. Joshi V. Elsevier India
  3. Practical Physiology by Dr. Vijaya Joshi andDr. S.D. Joshi

ACADEMIC YEAR: 2015-16