Center for Regenerative Medicine
regenerativemedicine.osu.edu
Center for Regenerative Medicine
and Cell Based Therapies (CRMCBT)
1stAnnualRetreat
August 17 – 18, 2012
Mohican State Park Lodge
Friday, 8/17/12
8:30 AM – 9:00AM Welcome and Opening Remarks
Chandan Sen, Ph.D.
Director, Center for Regenerative Medicine and Cell Based Therapies
Associate Dean, Translational & Applied Research
Professor and Vice-Chairman, Surgery
Director, OSU Comprehensive Wound Center
Deputy Director, Davis Heart and Lung Research Institute
Steven Gabbe, M.D.(Video)
Senior Vice President, Office of Health Sciences
CEO, Wexner Medical Center, Ohio State University (OSU)
E. Christopher Ellison, M.D.
Vice Dean for Clinical Affairs, College of Medicine
Associate Vice President, Clinical Affairs
Jeremy Rich, M.D.
Co-Director,National Center for Regenerative Medicine (NCRM)
Chairman, Department of Stem Cell Biology and Regenerative Medicine Lerner Research Institute Cleveland Clinic.
9:00AM to 12:00PM First Session
9:00AM to 10:00AM The Development and Translation of Tissue Engineered Vascular Graft
Toshiharu Shin Oka, M.D., Ph.D., Co-Director, Tissue Engineering Program, Nationwide Children’s Hospital, Pediatric Surgery, OSU
Translational Research a Two Way Street
Chris Breuer, M.D., Deputy Vice Chair of Research, Director, Tissue Engineering Program, OSU, Co-Director, Tissue Engineering Program, Nationwide Children’s Hospital
A Closed System Approach to Manufacture of a TEVG: Why Do I Prefer Thee?---Let Me Count the Ways
Edward Snyder, MD, FACP, Professor Laboratory Medicine, Yale University Medical School, Director, Transfusion/Apheresis/Tissue/Cell Processing Services, Yale-New Haven Hospital
Panel Discussion
10:00AM to 11:00PMReverse Tissue Engineering
Jed Johnson, Ph.D., Chief Technology Officer, Nanofiber Solutions
Computational Modeling and Bone Tissue Engineering
Michael Miller, M.D., Professor and Chair, Plastic Surgery, OSU
Bone and Cartilage Tissue Engineering, CTP and Stem Cell Biology
George Muschler, M.D., Staff Surgeon, Orthop. Surgery, Director, Orthop. Res. Ctr., Dir., Clin. Tissue Eng. Ctr., Staff, Dept. of Biomed. Eng., Cleveland Clinic, NCRM
Use of animal stem cells in preclinical models
Alicia Bertone, DVM, Ph.D., Diplomate ACVS, TheTrueman Chair in Equine Clinical Medicine and Surgery, OSU
Panel Discussion
11:00AM to 12:00PMTissue Engineering: Challenges in Multi-cellular Organization
Keith Gooch, Ph.D., Associate Professor, Biomedical Engineering, OSU
Engineering Tools from Cells to Biomaterials
Horst von Recum, Ph.D., Associate Professor, Biomedical Engineering and Macromolecular Science and Engineering, Case Western Reserve University (CWRU)
Multi-scale Biomaterials for Stem Cell Based Therapy and Tissue Regeneration
Xiaoming (Shawn) He, Ph.D., Associate Professor, Biomedical Engineering, OSU
Micro- and Nanofabricated Polymer Structures for Tissue Engineering and Cell Biology
Derek Hansford, Ph.D., Associate Professor, Biomedical Engineering
Associate Professor, Materials Science Engineering, OSU
Panel Discussion
12:00PM to 1:00PMLunch
1:00PM to 5:15PMSecond Session
1:00PM to 2:00PMProtein therapeutics targeting cell membrane repair for regenerative medicine
Jianjie Ma, Ph.D.,Director, Division of Molecular Medicine, OSU
Wounds: The Threshold for Human Applications of Regenerative Medicine
Gayle Gordillo,M.D., FACS, Associate Professor of Plastic Surgery, OSU
The Wound-Site Macrophage and Healing
Sashwati Roy, Ph.D., Associate Professor, Department of Surgery, Director, Laser Capture Molecular Core, OSU
Skin Tissue Engineering
Heather M. Powell, Ph.D., Assistant Professor, Department of Materials Science and Engineering and Biomedical Engineering, OSU
Panel Discussion
2:00PM to 3:00PMUse of Circulating Endothelial Progenitors in Cell- and Tissue-Engineering Applications
Nicanor I. Moldovan, Ph.D., Research Assoc. Professor, Cardiovascular and Internal Medicine, Investigator, Davis Heart and Lung Research Inst., OSU
Hematopoietic Stem Cells in Regenerative Medicine
Hiranmoy Das, Ph.D., Associate Professor, Cardiovascular and Int. Medicine, OSU
Stem Cell-Based Cardiac Tissue Engineering
Jianjun Guan, Ph.D., Assistant Professor, Department of Materials Science and Engineering, OSU
Stem Cells to Model Neurodegenerative Disease
Brian Kaspar, Ph.D., Associate Professor, Department of Pediatrics and Children's Research Institute, OSU
Panel Discussion
3:00PM to 4:00PMNew Paradigms for Human Excitable Cell Disease
Peter Mohler, Ph.D., Director DHLRI/Professor, Heart and Lung Institute, SBS-Physiology & Cell Biology, Associate Dean, Basic Sciences, ADM-Medicine Administration, OSU
Bio-Inspired Adhesives and Coatings
Ali Dhinojwala, PhD, Department Chair, H. A. Morton Professor of Polymer Science, University of Akron
Integrating Implementation Sciences into Tissue Engineering and Regenerative Medicine Research and Development
Samir Ghadiali, Ph.D, MS, Associate Professor, Biomedical Engineering,
Associate Professor, Pulm, Allergy, Crit Care & Sleep, OSU
Sensorimotor Recovery and Neural Plasticity Following Acute Ischemic Stroke
Cameron L. Rink, Ph.D., Assistant Professor, Surgery, OSU
Panel Discussion
4:00PM to 5:15PMUse of patient-derived cancer stem cells for translational research
Ichiro Nakano, M.D., Ph.D.,Neurological Surgery, OSU
Know thy enemy - the development of experimental imaging models to interrogate the complexity of cancer stem cells
Justin Lathia, Ph.D. Assistant Staff, Lerner Research Institute, Cleveland Clinic, Cell Biology, NCRM
Cancer Stem Cells
Jeremy Rich, M.D., Chair and Staff, Dept. Stem Cell Biology and Regenerative Med., Cleveland Clinic, Staff, Dept. of Neurology, Taussig Cancer Center, & Brain Tumor Center, CCF, Co-Director, The Center for Stem Cell and Regenerative Medicine, NCRM, Professor, Cleveland Clinic Lerner College of Medicine at Case Western
Myoferlin controls the motility cycle in human breast tumor cells
Douglas Kniss, Dir-Chemical Instrument Center, Chemical Instrumentation Ctr
Professor, SBS-Biomedical Informatics, Obstetrics & Gynecology, Pediatrics, OSU
Hyperthermia Sensitizes Glioblastoma Initiating Cells to Radiation
Jennifer Yu, MD, PhD, Associate Staff, Radiation Oncology, Adjunct Staff, Stem Cell Biology and Regenerative Medicine, Cleveland Clinic, NCRM
Panel Discussion
6:00PM to 8:00PMCookout (not mandatory)
8:00PM to 9:00PMEvening Breakout Third Session
Theme Breakout Sessions (Tissue Engineering, Stem Cell, Imaging, Wound Care)
Group Leaderswill present on Saturday
Saturday, 8/18/12
7:00AM to 7:30AMBreakfast(Continental)
7:30AM to 1:00PMFourth Session
7:30AM to 8:30 AMHematopoietic Stem Cells: Collection and Processing
Scott Scrape, M.D., Director of Biorepository and Biospecimen Resource,
Department of Pathology, Comprehensive Cancer Center, OSU
From Bench to Bedside: Translational Development for Cell and Tissue-Based Therapies
Lynn O'Donnell, Ph.D., Director, Cell Therapy Laboratory, OSU
Understanding the Targeting/Internalization Mechanisms of Cell Signaling by Cell-Secreted Microvesicles
Mike Paulaitis, Ph.D., Ohio Eminent Scholar Professor, Director, Institute in Multi-scale Modeling of Biological Interactions, Chemical and Biomolecular Engineering, OSU
NF-kB Signaling in Skeletal Muscle Regeneration
Denis C. Guttridge, Ph.D., Associate Professor, Molecular Virology, Immunology & Medical Genetics, OSU
Panel Discussion
8:30AM to 9:30 AMHigh-Definition Dynamic Capture of Bone Marrow Microenvironment
Alex Huang, M.D., Ph.D., Assistant Professor, Pediatrics, Pathology and Biomedical Engineering, CWRU, UHCMC
Mathematical Modelsin Tissue Formation and In Wound Healing at the MBI
Avner Friedman, Ph.D., Professor, Mathematical Biosciences Institute, OSU
Imaging approaches relevant for Regenerative Medicine and Cell-Based Therapies
Michael Knopp, M.D., Ph.D., Vice Chair of Research, Professor, Novartis Chair of Imaging Research, Director, Wright Center of Innovation in Biomedical Imaging
Division of Imaging Science, OSU
Tracking Cellular Events: In Vivo and In Vitro Imaging
Zhenghong Lee, Ph.D., Associate Professor, Radiology, Biomedical Engineering and General Medical Sciences (Oncology, Pediatrics), CWRU
Panel Discussion
9:30AM to 10:30 AM Cell-Based Product Manufacturing & Delivery
Herb Bresler, Ph.D., Chief Scientist, Health and Life Sciences Global Business, Battelle
Tissue Engineering by Controlling Stem Cell Fate in a High Cell Density System”
Eben Alsberg, Ph.D., Associate Professor, Biomedical Engineering and Orthopaedic Surgery, CWRU
Micro-/Nanoscale Technologies for Cell Reprogramming and Tissue Culture
Daniel Gallego Perez, Ph.D.,Postdoctoral Researcher, OSU
Sense & Sensibility” of Oxygen in Myocardial Infarction and Therapy
Periannan Kuppusamy, Ph.D, M.D.,(h.c.), D Litt, William D. and Jacquelyn L. Wells Chair in Imaging Research, Professor, Internal Medicine & Biomedical Engineering, Associate Director, Cardiovascular Medicine, OSU
Panel Discussion
10:30AM to 11:30 AMSuccesses and Challenges in Building National Consortia
Elizabeth Sump, B.S., Administrative Director, Orthopedic and Rheumatology Research, Cleveland Clinic, Director, Government Relations, Cleveland Clinic
Adjunct Instructor, Case Western Reserve University, Executive Director , Clinical Tissue Engineering Center, Cleveland Clinic
Developing a National Strategy for Regenerative Medicine – A Role for the NCRM
Gil Van Bokkelen, Ph.D., Chair, Board of Governors, National Center for Regenerative Medicine, NCRM, Founding Partner NCRM, CEO/Chairman/Founder Athersys
OH-Alive Innovator Platform: A Process Development and Manufacturing platform for Cell Therapy
Michael Gilkey, MBA, Marketing and Operations Manager, NCRM
Clinical Development of MultiStem
John Harrington, Ph.D., Executive Vice President & Chief Scientific Officer, Athersys, Inc., richExecutive Committee Member, NCRM
Panel Discussion
11:30AM to 1:00PM Breakout Speakers Presentations
Four group leaders will present discussion points from prior night Breakout Session
11:30AM to 11:45AMTissue Engineering
11:45AM to 12:00PMStem Cell
12:00AM to 12:15PMImaging
12:15PM to 12:30PMWound Care
12:30PM to 1:00PMPanel Discussion
1:00PMClosing Remarks
Chandan Sen
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