Table S1 The KEGG enrichment pathways of differentially expressed genes

Pathway names / P-value / Gene number
Breast vs Mantle
Asthma / 0.009529 / 7
Rheumatoid arthritis / 0.010248 / 15
Primary immunodeficiency / 0.010914 / 11
Protein processing in endoplasmic reticulum / 0.015881 / 25
Taste transduction / 0.017159 / 8
Epstein-Barr virus infection / 0.026659 / 31
Autoimmune thyroid disease / 0.029717 / 8
Dorso-ventral axis formation / 0.035248 / 10
Allograft rejection / 0.039137 / 7
Phenylalanine metabolism / 0.042316 / 5
Cell cycle / 0.049864 / 17
Nape vs Mantle
Tuberculosis / 0.00248 / 50
GABAergic synapse / 0.004119 / 28
Drug metabolism - other enzymes / 0.006265 / 11
NOD-like receptor signaling pathway / 0.006723 / 20
Pentose and glucuronate interconversions / 0.009242 / 8
Retrograde endocannabinoid signaling / 0.01119 / 29
p53 signaling pathway / 0.011736 / 23
Cell cycle / 0.013267 / 29
Allograft rejection / 0.018443 / 11
Morphine addiction / 0.02048 / 26
Phagosome / 0.028967 / 41
Dilated cardiomyopathy / 0.030255 / 50
Retinol metabolism / 0.033083 / 11
MAPK signaling pathway / 0.034771 / 56
Ascorbate and aldarate metabolism / 0.035275 / 5
African trypanosomiasis / 0.036597 / 12
HTLV-I infection / 0.039812 / 51
Vibrio cholerae infection / 0.043547 / 35
Primary immunodeficiency / 0.046528 / 14
GnRH signaling pathway / 0.046684 / 24
Autoimmune thyroid disease / 0.048439 / 11
Rump vs Mantle
Protein export / 0.002098 / 7
Epstein-Barr virus infection / 0.002347 / 38
MAPK signaling pathway / 0.003028 / 43
Progesterone-mediated oocyte maturation / 0.007463 / 17
NOD-like receptor signaling pathway / 0.010668 / 14
HTLV-I infection / 0.012849 / 37
Pyrimidine metabolism / 0.016391 / 19
Bile secretion / 0.01703 / 15
Endometrial cancer / 0.024112 / 11
Morphine addiction / 0.024376 / 18
Purine metabolism / 0.02743 / 28
Drug metabolism - other enzymes / 0.030022 / 7
GABAergic synapse / 0.035824 / 17
Chemokine signaling pathway / 0.037094 / 30

Table S2 The overlapped differentially expressed genes

Gene ID / Gene name / Description in Nr/Nt
Pictus_GLEAN_10014658 / DISP1 / Protein dispatched homolog 1
Pictus_GLEAN_10000108 / GART / Trifunctional purine biosynthetic protein adenosine-3
Pictus_GLEAN_10010005 / Gdf15 / Growth/differentiation factor 15
Pictus_GLEAN_10011222 / BFAR / Bifunctional apoptosis regulator
Pictus_GLEAN_10012474 / Slc5a7 / High affinity choline transporter 1
Pictus_GLEAN_10003211 / Unknown / Transmembrane protein C9orf91 homolog
Pictus_GLEAN_10000348 / NFYA / Nuclear transcription factor Y subunit alpha
Pictus_GLEAN_10008738 / - / -
Pictus_GLEAN_10004368 / AIM1L / Absent in melanoma 1-like protein
Pictus_GLEAN_10005259 / Unknown / Antimicrobial peptide THP2
Pictus_GLEAN_10012008 / ASIC2 / Acid-sensing ion channel 2
Pictus_GLEAN_10012500 / STXBP5 / Syntaxin-binding protein 5
Pictus_GLEAN_10014876 / COMMD8 / COMM domain-containing protein 8
Pictus_GLEAN_10003225 / SH2D1A / SH2 domain-containing protein 1A
Pictus_GLEAN_10008440 / UVSSA / UV-stimulated scaffold protein A
Pictus_GLEAN_10001408 / Stk3 / Serine/threonine-protein kinase 3
Pictus_GLEAN_10004559 / - / -
Pictus_GLEAN_10013092 / SLC29A1 / Equilibrative nucleoside transporter 1
Pictus_GLEAN_10002330 / NFIX / Nuclear factor 1 X-type
Pictus_GLEAN_10015591 / ADAMTS6 / A disintegrin and metalloproteinase with thrombospondin motifs 6
Pictus_GLEAN_10003672 / Pax5 / Paired box protein Pax-5
Pictus_GLEAN_10016591 / - / -
Pictus_GLEAN_10003044 / STAG1 / Cohesin subunit SA-1
Pictus_GLEAN_10014897 / - / -
Pictus_GLEAN_10004422 / MTERFD3 / mTERF domain-containing protein 3, mitochondrial
Pictus_GLEAN_10015534 / HEXB / Beta-hexosaminidase subunit beta
Pictus_GLEAN_10010980 / SMIM5 / Small integral membrane protein 5
Pictus_GLEAN_10004217 / ALMS1 / Alstrom syndrome protein 1
Pictus_GLEAN_10002454 / Rcan1 / Calcipressin-1
Pictus_GLEAN_10001753 / PAF1 / RNA polymerase II-associated factor 1 homolog
Pictus_GLEAN_10009937 / RPE65 / Retinoid isomerohydrolase
Pictus_GLEAN_10016196 / mfhas1 / Malignant fibrous histiocytoma-amplified sequence 1 homolog
Pictus_GLEAN_10004574 / - / -
Pictus_GLEAN_10012457 / AK3 / GTP:AMP phosphotransferase, mitochondrial
Pictus_GLEAN_10012216 / PEMT / Phosphatidylethanolamine N-methyltransferase
Pictus_GLEAN_10014346 / - / -
Pictus_GLEAN_10011735 / EYA1 / Eyes absent homolog 1
Pictus_GLEAN_10016118 / - / -
Pictus_GLEAN_10005108 / SCNN1A / Amiloride-sensitive sodium channel subunit alpha
Pictus_GLEAN_10013033 / Ssna1 / Sjoegren syndrome nuclear autoantigen 1 homolog
Pictus_GLEAN_10008204 / - / -
Pictus_GLEAN_10011762 / KLHL32 / Kelch-like protein 32
Pictus_GLEAN_10013038 / Rab18 / Ras-related protein Rab-18
Pictus_GLEAN_10013624 / IPO5 / Importin-5
Pictus_GLEAN_10002914 / PCDH15 / Protocadherin-15
Pictus_GLEAN_10010556 / Slc25a32 / Mitochondrial folate transporter/carrier
Pictus_GLEAN_10010087 / TENM3 / Teneurin-3
Pictus_GLEAN_10009788 / EIF3J / Eukaryotic translation initiation factor 3 subunit J
Pictus_GLEAN_10003779 / C21orf58 / Uncharacterized protein C21orf58
Pictus_GLEAN_10001877 / Cdkn2b / Cyclin-dependent kinase 4 inhibitor B
Pictus_GLEAN_10000247 / EFNA5 / Ephrin-A5
Pictus_GLEAN_10010108 / - / -
Pictus_GLEAN_10013900 / COG5 / Conserved oligomeric Golgi complex subunit 5
Pictus_GLEAN_10003784 / POFUT2 / GDP-fucose protein O-fucosyltransferase 2
Pictus_GLEAN_10013330 / DUSP13 / Dual specificity protein phosphatase 13
Pictus_GLEAN_10008736 / Dgkb / Diacylglycerol kinase beta
Pictus_GLEAN_10006805 / RAP1GAP / Rap1 GTPase-activating protein 1
Pictus_GLEAN_10010383 / Pithd1 / PITH domain-containing protein 1
Pictus_GLEAN_10007637 / isl2a / Insulin gene enhancer protein isl-2a
Pictus_GLEAN_10010311 / EIF2C4 / Protein argonaute-4
Pictus_GLEAN_10012322 / LIF / Leukemia inhibitory factor
Pictus_GLEAN_10004513 / CCDC102A / Coiled-coil domain-containing protein 102A
Pictus_GLEAN_10015988 / DDB2 / DNA damage-binding protein 2
Pictus_GLEAN_10011796 / NHLRC3 / NHL repeat-containing protein 3
Pictus_GLEAN_10009917 / HTR1D / 5-hydroxytryptamine receptor 1D (Fragment)
Pictus_GLEAN_10006460 / Prss57 / Serine protease 57