Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model

Mild TBI results in a long-term decrease in circulating phospholipids in a mouse model of injury

Journal of Neuromolecular Medicine

Authors: Tanja Emmerich1, 2, 3, Laila Abdullah1, 2, 3, Joseph Ojo1, 2, Benoit Mouzon1, 2, 3, Thinh Nguyen1, Gary S. Laco1, Gogce Crynen1, 2, James E. Evans1, 3, Jon Reed1, 3 and Fiona Crawford 1, 2, 3

Affiliations:

1. The Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL, 34243, U.S.A.

2. The Open University, Walton Hall,Milton Keynes, Buckinghamshire MK7 6AA, U.K.

3. James A. Haley Veteran’s Hospital, 13000 Bruce B. Downs Blvd., Tampa, FL, 33612.

Corresponding author:

Tanja Emmerich; The Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL, 34243, U.S.A.;

Authors:

Tanja Emmerich,, Dr. Laila Abdullah, , Dr. Joseph Ojo, , Dr. Benoit Mouzon, ; Thinh Nguyen, ; Dr. Gary S. Laco, ; Dr. GogceCrynen, ; James E. Evans, ; Jon Reed MS., ; Dr. Fiona Crawford, .

Supplement table 1:Totalplasma levels of PC, LPC, PE, LPE, PI and SM quantified by LC/MS analyses (μM± SEM).Individual molecular species of each class were quantified by LC/MS and summed after lipidomeDB analyses to generate total lipid levels. *denotes significant p values for all timepoints.

Supplement table 2:Plasma levels of PC molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.

Supplement table 3:Plasma levels of LPC molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.

Supplement table 4:Plasma levels of PE molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.

Supplement table 5:Plasma levels of LPE molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.

Supplement table 6:Plasma levels of PI molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.

Supplement table 7:Plasma levels of SM molecular species quantified by LC/MS analyses (μM± SEM).Phospholipids presented in each table are those that were significantly associated with PCA component within each class that was significantly associated with mTBI at given timepoints.