Mechanisms of Stem Cell Repair of the Heart

June 21, 2012

7:30 – 8:30 AM

11-146 Translational Research Center

Marc Penn, MD, PhD

Director of Research, Summa Cardiovascular Institute

Summa Health System

Professor of Medicine and Integrative Medical Sciences

Northeast Ohio Medical University

Target Audience

This program has been designed for cardiologists, CT surgeons, radiologists specializing in cardiovascular imaging, internists, clinical and basic scientists in medicine, biology, genetics, biomedical engineering, pharmacology, physiology and other specialties, PHDs and PhD candidates, cardiology and CT surgery fellows, medicine and surgery housestaff

Educational Objectives

After completing this activity, participants should be able to:

·  Describe evidence supporting the latest treatment for cardiac conditions (i.e., interventional procedures such as cardiac catheterization, cardiac biopsies, electrophysiologic studies), noninvasive cardiac procedures and clinical cardiology therapy

·  Review experimental data from translational and clinical studies with the potential to influence practice

·  Assess the results of clinical trials from a regional and national view

·  Assess patient care through discussing medical errors, complications and unanticipated outcomes

·  Gain practice-based learning and improvement through reviewing records, specifics and revisiting errors to gain insight without blame or derision

·  Recognize the importance of systems-based practice that explicitly depict the larger context and system health care by stressing the importance of collaborative efforts involving physicians and ancillary staff for safety and quality improvements

Accreditation

The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgement of Commercial Support*

NONE

For more information, please contact

Denice Susini

215-662-3140

Disclosure of Relevant Financial Relationships and Unapproved Uses of Products

It is policy at the Perelman School of Medicine at the University of Pennsylvania for individuals who are in a position to control the content of an educational activity to disclose to the learners all relevant financial relationships that they have with any commercial interest that provides products or services that may be relevant to the content of this continuing medical education activity. For this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner.

The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically rigorous and evidence-based presentations.

The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania and the peer reviewer(s) Zalman Agus, MD, Associate Dean for CME, have disclosed that they have no relevant financial relationships with any commercial interests related to the content of this educational activity.

The following individuals have disclosed that they have no relevant financial relationships with any commercial interests

related to the content of this educational activity:

Faculty Name

Joseph Carver, MD

Irving Herling, MD

Suraj Kapa, MD

Presenter Name

The following individuals have reported the listed relevant financial relationships with commercial interests related to the content of this educational activity.

Presenter Name Name of Commercial Interest Relationship

Michael S. Parmacek, MD Phillip Lyttle LLC Medical Expert

NHLBI Scientific Advisor

Lee Goldberg, MD Cardiac Concepts & Alere Medical Consultant

Presenter Name Name of Commercial Interest Relationship

Marc Penn, MD Juventas Therapeutics, Inc Founder/CMO

Ahersys, Inc. PI

Aastrom Biosciences, Inc. SAB member

BIOMET, Inc. DSMB member

SironRx Therapeutics Founder/CSO

Relevant Financial Relationships: Financial relationships are those relationships in which the individual benefits by receiving a salary, royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as employment, management position, independent contractor (including contracted research), consulting, speaking and teaching, membership on advisory committees or review panels, board membership, and other activities from which remuneration is received or expected

Disclosure of Unapproved Uses of Products

Presenter name Product Investigational and/or Off-label Use

Marc Penn, MD, PhD MultiStem investigational

JVS-100 investigational

Bone Marrow Cells investigational