Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
1,1,1-Trichloroethane / 71556 / 0 / 5
1,1,2,2-Tetrachloroethane / 79345 / 0.000058 / 0
1,1,2-Trichloroethane / 79005 / 0.000016 / 0.4
1,1-Dimethylhydrazine / 57147 / 0 / 0
Lindane (gamma-HCH) / 58899 / 0.00031 / 0.0003
1,2,4-Trichlorobenzene / 120821 / 0 / 0.2
1,2-Dibromo-3-chloropropane / 96128 / 0.002 / 0.0002
1,2-Epoxybutane / 106887 / 0 / 0.02
1,2-Propyleneimine / 75558 / 0 / 0
1,3-Butadiene / 106990 / 0.00003 / 0.002
1,3-Dichloropropene / 542756 / 0.000004 / 0.02
1,3-Propane sultone / 1120714 / 0.00069 / 0
p-Dichlorobenzene / 106467 / 0.000011 / 0.8
p-Dimethylaminoazobenzene / 60117 / 0.0013 / 0
1,4-Dioxane / 123911 / 0.0000077 / 3.6
2,2,4-Trimethylpentane / 540841 / 0 / 0
2,4,5-Trichlorophenol / 95954 / 0 / 0
2,4,6-Trichlorophenol / 88062 / 0.0000031 / 0
2,4-D, salts and esters / 94757 / 0 / 0
2,4-Dinitrophenol / 51285 / 0 / 0
2,4-Dinitrotoluene / 121142 / 0.000089 / 0.007
2,4-Toluene diamine / 95807 / 0.0011 / 0
2,4-Toluene diisocyanate / 584849 / 0.000011 / 0.00007
2-Nitropropane / 79469 / 0.0000056 / 0.02
3,3'-Dichlorobenzidine / 91941 / 0.00034 / 0
3,3'-Dimethoxybenzidine / 119904 / 0.000004 / 0
3,3'-Dimethylbenzidine / 119937 / 0.0026 / 0
4,4'-Methylene bis(2-chloroaniline) / 101144 / 0.00043 / 0
4,4'-Methylenedianiline / 101779 / 0.00046 / 0.02
Methylene diphenyl diisocyanate / 101688 / 0 / 0.0006
4,6-Dinitro-o-cresol / 534521 / 0 / 0
4-Aminobiphenyl / 92671 / 0 / 0
4-Nitrobiphenyl / 92933 / 0 / 0
4-Nitrophenol / 100027 / 0 / 0
Acetaldehyde / 75070 / 0.0000022 / 0.009
Acetamide / 60355 / 0.00002 / 0
Acetonitrile / 75058 / 0 / 0.06
Acetophenone / 98862 / 0 / 0
Acrolein / 107028 / 0 / 0.00002
Acrylamide / 79061 / 0.00016 / 0.006
Acrylic acid / 79107 / 0 / 0.001
Acrylonitrile / 107131 / 0.000068 / 0.002
Allyl chloride / 107051 / 0.000006 / 0.001
Aniline / 62533 / 0.0000016 / 0.001
Anisidine / 90040 / 0 / 0
Antimony compounds / 7440360 / 0 / 0.0002
Antimony oxide / 1327339 / 0 / 0.0002
Antimony trioxide / 1309644 / 0 / 0.0002
Arsenic acid / 7778394 / 0.0043 / 0.000015
Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
Arsenic compounds / 7440382 / 0.0043 / 0.000015
Arsenic pentoxide / 1303-28-2 / 0.0043 / 0.000015
Arsenic trioxide / 1327533 / 0.0043 / 0.000015
Arsine / 7784421 / 0 / 0.00005
Asbestos / 1332-21-4 / 0.00767 / 0
Benzene / 71432 / 0.0000078 / 0.03
Benzidine / 92875 / 0.1072 / 0.01
Benzotrichloride / 98077 / 0.0037 / 0
Benzyl chloride / 100447 / 0.000049 / 0
Beryllium compounds / 7440417 / 0.0024 / 0.00002
Beryllium oxide / 1304-56-9 / 0.0024 / 0.000007
Biphenyl / 92524 / 0 / 0
Bis(2-ethylhexyl)phthalate / 117817 / 0.0000024 / 0.01
Bis(chloromethyl)ether / 542881 / 0.062 / 0
Bromoform / 75252 / 0.0000011 / 0
Cadmium acetate / 543908 / 0.0018 / 0.00001
Cadmium compounds / 7440439 / 0.0018 / 0.00001
Cadmium nitrate / 10325947 / 0.0018 / 0.00001
Cadmium oxide / 1306190 / 0.0018 / 0.00001
Captan / 133062 / 0.000001 / 0
Carbaryl / 63252 / 0 / 0
Carbon disulfide / 75150 / 0 / 0.7
Carbon tetrachloride / 56235 / 0.000006 / 0.1
Carbonyl sulfide / 463581 / 0 / 0
Catechol / 120809 / 0 / 0
Chlordane / 57749 / 0.0001 / 0.0007
Chlorine / 7782505 / 0 / 0.00015
Chloroacetic acid / 79118 / 0 / 0
Chlorobenzene / 108907 / 0 / 1
Chlorobenzilate / 510156 / 0.000078 / 0
Chloroform / 67663 / 0 / 0.098
Chloromethyl methyl ether / 107302 / 0 / 0
Chloroprene / 126998 / 0 / 0.007
Ammonium chromate / 7788989 / 0.012 / 0.0001
Barium chromate / 10294403 / 0.012 / 0.0001
Calcium chromate / 13765190 / 0.012 / 0.0001
Chromic acid (VI) / 7738-94-5 / 0.012 / 0.0001
Chromic oxide / 1308389 / 0 / 0
Chromic sulfate / 10101538 / 0 / 0
Chromic sulfuric acid / 13530682 / 0.012 / 0.0001
Chromium (III) compounds / 16065831 / 0 / 0
Chromium (VI) as Lead chromate / 7758976 / 0.012 / 0.0001
Chromium (VI) compounds / 18540299 / 0.012 / 0.0001
Chromium (VI) trioxide, chromic acid mist / 11115745 / 0 / 0.000008
Chromium chloride / 10025-73-7 / 0 / 0
Chromium zinc oxide / 12018198 / 0 / 0
Potassium chromate / 7789006 / 0.012 / 0.0001
Potassium dichromate / 7778509 / 0.012 / 0.0001
Sodium chromate / 7775113 / 0.012 / 0.0001
Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
Sodium dichromate / 10588019 / 0.012 / 0.0001
Strontium chromate / 7789062 / 0.012 / 0.0001
Zinc chromate / 13530659 / 0.012 / 0.0001
Zinc chromite / 50922297 / 0 / 0
Zinc potassium chromate / 11103869 / 0.012 / 0.0001
Cobalt aluminate / 1345160 / 0 / 0.0001
Cobalt compounds / 7440484 / 0 / 0.0001
Cobalt hydrocarbonyl / 16842-03-8 / 0 / 0.0001
Cobalt oxide / 1307966 / 0 / 0.0001
Cobalt oxide (ii,iii) / 1308061 / 0 / 0.0001
Hexanoic acid, 2-ethyl-, cobalt(2+) salt / 136527 / 0 / 0.0001
Benzene soluble organics (BSO) / 141 / 0.00062 / 0
Coke oven emissions / 8007452 / 0.00062 / 0
Methylene chloride soluble organics (MCSO) / 142 / 0.00062 / 0
Cresols (mixed) / 1319773 / 0 / 0.6
m-Cresol (3-methylphenol) / 108394 / 0 / 0.6
o-Cresol / 95487 / 0 / 0.6
p-Cresol (4-methy phenol) / 106445 / 0 / 0.6
Cumene / 98828 / 0 / 0.4
2-Methyl-Propanenitrile / 78820 / 0 / 0.003
Calcium cyanamide / 156-62-7 / 0 / 0.003
Copper cyanide / 544923 / 0 / 0.003
Cyanide compounds / 57125 / 0 / 0.003
Hydrogen cyanide / 74908 / 0 / 0.003
Potassium cyanide / 151508 / 0 / 0.003
Sodium cyanide / 143339 / 0 / 0.003
Zinc cyanide / 557211 / 0 / 0.003
DDE (1,1-Dichloro-2,2-bis(p-chlorophenyl) ethylene / 72559 / 0.000097 / 0
Diazomethane / 334-88-3 / 0 / 0
Dibenzofuran / 132649 / 0 / 0
Dibutylphthalate / 84742 / 0 / 0
Dichloroethyl ether / 111444 / 0.00033 / 0
Dichlorvos / 62737 / 0.000083 / 0.0005
Diethanolamine / 111422 / 0 / 0.003
Diethyl Sulfate / 64675 / 0 / 0
Dimethyl formamide / 68122 / 0 / 0.03
Dimethyl phthalate / 131113 / 0 / 0
Dimethyl sulfate / 77781 / 0 / 0
Dimethylcarbamoyl chloride / 79447 / 0 / 0
Epichlorohydrin / 106898 / 0.0000012 / 0.001
Ethyl acrylate / 140885 / 0 / 0
Ethyl benzene / 100414 / 0.0000025 / 1
Ethyl carbamate / 51796 / 0.000464 / 0
Ethyl chloride / 75003 / 0 / 10
Ethylene dibromide / 106934 / 0.0006 / 0.009
Ethylene dichloride / 107062 / 0.000026 / 2.4
Ethylene glycol / 107211 / 0 / 0.4
Ethylene imine (aziridine) / 151564 / 0 / 0
Ethylene oxide / 75218 / 0.000088 / 0.03
Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
Ethylene thiourea / 96457 / 0.000013 / 0.003
Ethylidene dichloride / 75343 / 0.0000016 / 0.5
Fine mineral fibers / 383 / 0 / 0
Formaldehyde / 50000 / 0.000013 / 0.0098
(Ethylenebis(Oxyethylenenitrilo)) tetraacetic acid / 67425 / 0 / 0.02
1,2-Dimethoxyethane / 110714 / 0 / 0.02
2-(Hexyloxy)Ethanol / 112254 / 0 / 0.02
2-Butoxyethyl acetate / 112072 / 0 / 0.02
3-Methoxy-1-propanol / 1589497 / 0 / 0.02
Butyl carbitol acetate / 124174 / 0 / 0.02
Carbitol acetate / 112152 / 0 / 0.02
Di(ethylene glycol monobutyl ether) phthalate / 16672392 / 0 / 0.02
Diethylene glycol dibenzoate / 120558 / 0 / 0.02
Diethylene glycol diethyl ether / 112367 / 0 / 0.02
Diethylene glycol dimethyl ether / 111966 / 0 / 0.02
Diethylene glycol ethyl methyl ether / 1002671 / 0 / 0.02
Diethylene glycol monobutyl ether / 112345 / 0 / 0.02
Diethylene glycol monoethyl ether / 111900 / 0 / 0.02
Diethylene glycol monomethyl ether / 111773 / 0 / 0.02
Ethoxytriglycol / 112-50-5 / 0 / 0.02
Ethylene glycol diethyl ether / 629141 / 0 / 0.02
Ethylene glycol ethyl ether / 110805 / 0 / 0.2
Ethylene glycol ethyl ether acetate / 111159 / 0 / 0.3
Ethylene glycol methyl ether / 109864 / 0 / 0.02
Ethylene glycol methyl ether acetate / 110496 / 0 / 0.09
Ethylene glycol mono-sec-butyl ether / 7795917 / 0 / 0.02
Ethylene glycol monovinyl ether / 0 / 0.02
Glycol ethers / 171 / 0 / 0.02
Methoxytriglycol / 112356 / 0 / 0.02
N-Hexyl carbitol / 112594 / 0 / 0.02
Phenyl Cellosolve / 122996 / 0 / 0.02
Triethylene glycol / 112276 / 0 / 0.02
Triglycol monobutyl ether / 143226 / 0 / 0.02
Heptachlor / 76448 / 0.0013 / 0
Hexachlorobenzene / 118741 / 0.00046 / 0.003
Hexachlorobutadiene / 87683 / 0.000022 / 0.09
Hexachlorocyclopentadiene / 77474 / 0 / 0.0002
Hexachloroethane / 67721 / 0.000004 / 0.08
Hexamethylene-1,6-diisocyanate / 822060 / 0 / 0.00001
n-Hexane / 110543 / 0 / 0.7
Hydrazine / 302012 / 0.0049 / 0.0002
Hydrochloric acid / 7647010 / 0 / 0.02
Hydrofluoric acid / 7664393 / 0 / 0.014
Hydroquinone / 123319 / 0 / 0
Isophorone / 78591 / 0.00000027 / 2
Lead (II) oxide / 1317368 / 0 / 0.00015
Lead as Lead arsenate / 7784409 / 0 / 0.00015
Lead as Lead chromate oxide / 18454121 / 0 / 0.00015
Lead compounds / 7439921 / 0 / 0.00015
Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
Lead dioxide / 1309600 / 0 / 0.00015
Lead subacetate / 1335326 / 0 / 0.00015
Lead sulfate / 7446142 / 0 / 0.00015
Maleic anhydride / 108316 / 0 / 0.0007
Manganese compounds / 7439965 / 0 / 0.00005
Manganese dioxide / 1313139 / 0 / 0.00005
Manganese nitrate / 10377669 / 0 / 0.00005
Manganese sulfate / 7785877 / 0 / 0.00005
Manganese tetroxide / 1317357 / 0 / 0.00005
Manganese trioxide / 1317346 / 0 / 0.00005
Mercuric chloride / 7487947 / 0 / 0.00003
Mercury (elemental) / 7439976 / 0 / 0.0003
Mercury (organic) / 22967926 / 0 / 0.00003
Methanol / 67561 / 0 / 4
Methoxychlor / 72435 / 0 / 0
Methyl bromide / 74839 / 0 / 0.005
Methyl chloride / 74873 / 0 / 0.09
Methyl hydrazine / 60344 / 0 / 0
Methyl iodide / 74884 / 0 / 0
Methyl isobutyl ketone / 108101 / 0 / 3
Methyl isocyanate / 624839 / 0 / 0.001
Methyl methacrylate / 80626 / 0 / 0.7
Methyl tert-butyl ether / 1634044 / 0.00000026 / 3
Methylene chloride / 75092 / 0.00000047 / 1
N,N-dimethylaniline / 121697 / 0 / 0
Naphthalene / 91203 / 0.000034 / 0.003
Nickel (II) sulfate hexahydrate / 10101970 / 0.000312 / 0.00009
Nickel acetate / 373024 / 0.000312 / 0.00009
Nickel chloride / 7718549 / 0.000312 / 0.00009
Nickel compounds / 7440020 / 0.000312 / 0.00009
Nickel nitrate / 13138459 / 0.000312 / 0.00009
Nickel oxide / 1313991 / 0 / 0.0001
Nickel sulfamate / 13770893 / 0.000312 / 0.00009
Nickel sulfate / 7786814 / 0.000312 / 0.00009
Nitrobenzene / 98953 / 0.00004 / 0.009
Nitrosodimethylamine / 62759 / 0.014 / 0
N-Nitrosomorpholine / 59892 / 0.0019 / 0
o-Toluidine / 95534 / 0.000051 / 0
Pentachloronitrobenzene / 82688 / 0.000074 / 0
Pentachlorophenol / 87865 / 0.0000051 / 0.1
Phenol / 108952 / 0 / 0.2
Phosgene / 75445 / 0 / 0.0003
Phosphine / 7803512 / 0 / 0.0003
Phosphorus, white / 7723140 / 0 / 0
Phthalic anhydride / 85449 / 0 / 0.02
Polychlorinated biphenyls / 1336363 / 0.0001 / 0
2-Acetylaminofluorene / 53-96-3 / 0 / 0
2-Chloroacetophenone / 532274 / 0 / 0.00003
POM 71002 / 0.000088 / 0
Supplemental Table 1: Toxicity Values Used in the 2005 NATA
Chemical Name / CAS Number / Inhalation Unit RiskEstimate (URE),
1/(μg/m3) / Reference Concentration (RfC), mg/m3
POM 72002 / 0.000088 / 0
POM 73002 / 0.16 / 0
POM 74002 / 0.016 / 0
POM 75002 / 0.0016 / 0
POM 76002 / 0.00016 / 0
POM 77002 / 0.000016 / 0
POM 78002 / 0.00032 / 0
p-Phenylenediamine / 106503 / 0 / 0
Propionaldehyde / 123386 / 0 / 0.008
Propoxur / 114261 / 0 / 0
Propylene dichloride / 78875 / 0.000019 / 0.004
Propylene oxide / 75569 / 0.0000037 / 0.03
Quinoline / 91225 / 0 / 0
Quinone / 106514 / 0 / 0
Radionuclides / 605 / 0 / 0
Radon and its decay products / 606 / 0 / 0
Uranium / 7440611 / 0 / 0.0003
Selenium compounds / 7782492 / 0 / 0.02
Selenium dioxide / 7446084 / 0 / 0.02
Selenium hexafluoride / 7783791 / 0 / 0.02
Selenium oxide / 12640890 / 0 / 0.02
Styrene / 100425 / 0 / 1
Styrene oxide / 96093 / 0 / 0.006
Tetrachloroethene / 127184 / 0.0000059 / 0.27
Titanium tetrachloride / 7550450 / 0 / 0.0001
Toluene / 108883 / 0 / 5
Toxaphene / 8001352 / 0.00032 / 0
Trichloroethylene / 79016 / 0.000002 / 0.6
Triethylamine / 121448 / 0 / 0.007
Trifluralin / 1582098 / 0.0000022 / 0
Vinyl acetate / 108054 / 0 / 0.2
Vinyl bromide / 593602 / 0.000032 / 0.003
Vinyl chloride / 75014 / 0.0000088 / 0.1
Vinylidene chloride / 75354 / 0 / 0.2
m-Xylene / 108383 / 0 / 0.1
o-Xylene / 95476 / 0 / 0.1
p-Xylene / 106423 / 0 / 0.1
Xylenes (mixed) / 1330207 / 0 / 0.1