Journal Name: Structural Chemistry

Supplementary Material

The Role of Cesium Fluoride in Aryl Propargyl Ether Claisen Rearrangement and its Mechanistic Elucidation: A Theoretical Study.

MengistuGemech Menkir1,VenkatesanSrinivasadesikan2 and Shyi-LongLee1,

1Department of Chemistry and Biochemistry, National Chung Cheng University,Chia-Yi, Taiwan.

2Department of Chemistry, National Chiao Tung University, Hsinchu, Taiwan.

Corresponding authorE-mail:

TableS1. The relative free energies for all speciesin the reaction in gas and solvent phases at M06/6-31+G(d,p)/LANL2DZ// B3LYP/6-31+G(d)/LANL2DZ level. (Unit: kcalmol-1) The optimized geometry of Ts2a-CsF in gas phase is not found.

M06/6-31+G(d,p)/LANL2DZ// B3LYP/6-31+G(d)/LANL2DZ
Gas / Solvent
1-CsF / 0.0 / 0.0
Ts1-CsF / 39.2 / 37.1
Int1-CsF / 6.4 / -3.4
Ts2a-CsF / --- / -2.1
Int2a + HF / -18.6 / -19.8
Ts3a-CsF / -5.3 / -8.9
Product A + CsF / -50.3 / -49.4
Ts2b-CsF / 51.1 / 50.6
Int2b-CsF / -36.4 / -27.0
Ts3b-CsF / -0.2 / 5.6
Int3b-CsF / -23.0 / -21.9
Ts4b-CsF / -11.8 / -12.2
Int4b-CsF / -8.3 / -16.2
Ts5b-CsF / -7.0 / -4.2
Product B + CsF / -34.7 / -34.1

Cartesian coordinates (Ǻ) for optimizedstructures in N,N-diethylaniline at B3LYP/6-31G(d)/LANL2DZ level with PCM model.The coordinates of the optimized structures in gas phase are not included.

1

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -2.617767 -0.573337 0.495153

2 6 0 -2.756273 0.762512 0.094996

3 6 0 -1.642468 1.444402 -0.396665

4 6 0 -0.395213 0.813267 -0.495417

5 6 0 -0.271318 -0.523754 -0.099074

6 6 0 -1.385034 -1.215959 0.400245

7 8 0 0.891716 -1.256175 -0.163514

8 6 0 2.065928 -0.662943 -0.726892

9 6 0 2.734259 0.282733 0.175044

10 6 0 3.307753 1.050107 0.914079

11 1 0 -3.474581 -1.119308 0.881771

12 1 0 -3.718138 1.262007 0.169323

13 1 0 -1.731119 2.482933 -0.705498

14 1 0 0.456234 1.374379 -0.863209

15 1 0 -1.265233 -2.251887 0.704225

16 1 0 2.728070 -1.508470 -0.933136

17 1 0 1.828171 -0.184104 -1.685529

18 1 0 3.803660 1.731680 1.571351

CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 55 0 0.000000 0.000000 0.404130

2 9 0 0.000000 0.000000 -2.469682

1-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 4.910943 -1.542987 0.021937

2 6 0 3.970034 -2.386441 0.625918

3 6 0 2.627776 -1.995491 0.658641

4 6 0 2.207173 -0.780391 0.102772

5 6 0 3.162955 0.055701 -0.492033

6 6 0 4.513140 -0.324888 -0.531302

7 8 0 2.868014 1.253238 -1.103478

8 6 0 1.652435 1.943069 -0.743888

9 6 0 1.779102 2.628588 0.548389

10 6 0 1.878011 3.205285 1.609270

11 1 0 5.959620 -1.828807 -0.013495

12 1 0 4.279484 -3.332871 1.061763

13 1 0 1.885753 -2.645674 1.117205

14 1 0 1.150862 -0.511930 0.104007

15 1 0 5.233724 0.342332 -0.996388

16 1 0 1.517280 2.679962 -1.541729

17 1 0 0.776650 1.272021 -0.737032

18 1 0 1.969056 3.701877 2.550701

19 55 0 -3.615306 -0.288206 0.007864

20 9 0 -0.787123 0.148204 -0.438658

Ts1-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 3.450822 -1.302813 -1.140993

2 6 0 3.477981 -1.735794 0.214230

3 6 0 2.539763 -1.265113 1.105248

4 6 0 1.549186 -0.309026 0.703226

5 6 0 1.470889 0.047884 -0.692849

6 6 0 2.491963 -0.413849 -1.580699

7 8 0 0.545874 0.869846 -1.103197

8 6 0 0.930949 2.689146 -0.463595

9 6 0 1.705247 2.446434 0.642789

10 6 0 2.234536 1.561325 1.363341

11 1 0 4.195995 -1.682159 -1.836618

12 1 0 4.232577 -2.450221 0.533068

13 1 0 2.544654 -1.603899 2.138717

14 1 0 0.651704 -0.199506 1.325489

15 1 0 2.462525 -0.080409 -2.615093

16 1 0 1.403688 3.037533 -1.378509

17 1 0 -0.104305 2.994013 -0.334690

18 1 0 2.854380 1.328196 2.207983

19 55 0 -2.402151 -0.280109 -0.240410

20 9 0 -1.066437 -0.356162 2.344842

Int1-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 3.373625 -1.696071 -0.911110

2 6 0 3.734536 -1.337678 0.441380

3 6 0 2.953460 -0.478618 1.138260

4 6 0 1.676762 0.063869 0.597233

5 6 0 1.387172 -0.242209 -0.855110

6 6 0 2.266522 -1.192016 -1.526114

7 6 0 1.440805 1.498290 1.052607

8 6 0 1.403296 2.572084 0.302669

9 6 0 1.345940 3.660351 -0.426885

10 8 0 0.393626 0.236882 -1.435962

11 1 0 4.019558 -2.383372 -1.454416

12 1 0 4.636502 -1.756826 0.878454

13 1 0 3.220751 -0.190435 2.153022

14 1 0 0.841121 -0.539511 1.141869

15 1 0 2.022034 -1.447598 -2.553977

16 1 0 1.321945 1.616506 2.131204

17 1 0 2.238238 4.241115 -0.657257

18 1 0 0.405611 4.022282 -0.841662

19 55 0 -2.461266 -0.215648 -0.088457

20 9 0 -0.441987 -1.187174 1.853110

Ts2a-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 3.523121 -1.496506 -0.854265

2 6 0 3.853430 -1.035721 0.471684

3 6 0 3.004064 -0.198603 1.118331

4 6 0 1.691099 0.194496 0.554190

5 6 0 1.434637 -0.188202 -0.878164

6 6 0 2.381036 -1.110236 -1.493202

7 6 0 1.255747 1.576842 1.005428

8 6 0 0.926281 2.606663 0.263961

9 6 0 0.586661 3.661266 -0.438099

10 8 0 0.415450 0.195304 -1.489853

11 1 0 4.218745 -2.163087 -1.360904

12 1 0 4.784263 -1.355801 0.931286

13 1 0 3.247031 0.170580 2.112973

14 1 0 0.916107 -0.523402 1.112308

15 1 0 2.159851 -1.438152 -2.505750

16 1 0 1.243857 1.707725 2.089572

17 1 0 1.326745 4.388002 -0.771114

18 1 0 -0.445874 3.847395 -0.732719

19 55 0 -2.377750 -0.341927 -0.061589

20 9 0 -0.214950 -1.272191 1.770156

Int2a

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -3.815948 -1.750022 0.000282

2 6 0 -4.526537 -0.543758 -0.139883

3 6 0 -3.807863 0.651628 -0.141779

4 6 0 -2.405381 0.689114 -0.012976

5 6 0 -1.657052 -0.541079 0.129889

6 6 0 -2.431795 -1.748776 0.132249

7 6 0 -1.748303 1.996402 -0.026488

8 6 0 -0.474283 2.346164 0.047496

9 6 0 0.731310 2.867534 0.111973

10 8 0 -0.372409 -0.551807 0.246370

11 1 0 -4.354109 -2.697381 0.006273

12 1 0 -5.608679 -0.540406 -0.242578

13 1 0 -4.342823 1.595853 -0.247913

14 1 0 -1.888397 -2.686211 0.241792

15 1 0 -2.437049 2.842409 -0.112756

16 1 0 1.196774 3.130686 1.063965

17 1 0 1.324407 3.067144 -0.783098

18 55 0 2.543714 -0.438198 -0.045477

HF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 9 0 0.000000 0.000000 0.094093

2 1 0 0.000000 0.000000 -0.846840

Ts3a-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 3.134759 -2.237653 0.168006

2 6 0 4.264251 -1.425863 -0.040090

3 6 0 4.102774 -0.042097 -0.163676

4 6 0 2.823197 0.519746 -0.081137

5 6 0 1.665934 -0.293193 0.125830

6 6 0 1.850932 -1.693072 0.251461

7 6 0 2.454981 1.913892 -0.179011

8 6 0 1.189457 2.317366 -0.075665

9 6 0 0.180108 3.234523 -0.039705

10 8 0 0.526613 0.343008 0.182218

11 1 0 3.261336 -3.314188 0.268603

12 1 0 5.254100 -1.870416 -0.101682

13 1 0 4.968159 0.599449 -0.322202

14 1 0 -1.187085 2.541760 0.216195

15 1 0 0.990438 -2.337547 0.419560

16 1 0 3.210937 2.682199 -0.340422

17 1 0 -0.127285 3.697475 -0.981832

18 1 0 0.106405 3.878481 0.841347

19 55 0 -2.382546 -0.769005 -0.083279

20 9 0 -2.183140 2.212459 0.369659

ProductA

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -2.547110 -0.796004 0.000076

2 6 0 -2.639062 0.610309 0.000082

3 6 0 -1.496763 1.412412 0.000047

4 6 0 -0.238999 0.786836 -0.000066

5 6 0 -0.183590 -0.620655 -0.000117

6 6 0 -1.305809 -1.440212 -0.000008

7 6 0 1.137807 1.224111 -0.000163

8 6 0 1.908778 0.102522 -0.000001

9 8 0 1.124289 -1.039460 -0.000154

10 1 0 -3.455759 -1.391851 0.000120

11 1 0 -3.620487 1.077368 0.000096

12 1 0 -1.579891 2.496147 0.000075

13 1 0 -1.219829 -2.522607 0.000118

14 1 0 1.505509 2.241825 -0.000120

15 6 0 3.379099 -0.120855 0.000175

16 1 0 3.901931 0.839450 0.000416

17 1 0 3.693905 -0.687791 0.885252

18 1 0 3.694211 -0.687651 -0.884870

Ts2b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -4.292014 -2.028152 -0.680898

2 6 0 -2.934803 -2.352432 -0.389196

3 6 0 -2.080470 -1.395071 0.119039

4 6 0 -2.580642 -0.074602 0.399506

5 6 0 -4.028641 0.095696 0.345948

6 6 0 -4.855783 -0.798494 -0.366352

7 6 0 -1.616069 1.041602 0.045307

8 6 0 -1.908822 2.246169 -0.382967

9 6 0 -2.177623 3.462884 -0.796835

10 8 0 -4.388176 0.987162 1.231497

11 1 0 -4.925722 -2.793526 -1.124388

12 1 0 -2.567568 -3.346119 -0.629635

13 1 0 -1.005525 -1.553479 0.213158

14 1 0 -3.068263 0.627610 1.527937

15 1 0 -5.915484 -0.598998 -0.496819

16 1 0 -0.572739 0.714672 0.164200

17 1 0 -2.295791 3.699437 -1.854657

18 1 0 -2.304187 4.290965 -0.098257

19 55 0 3.782878 -0.093522 -0.014675

20 9 0 0.950177 -0.553306 0.388031

Int2b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -3.498067 -2.478065 0.317453

2 6 0 -4.253566 -1.841383 -0.674494

3 6 0 -3.974981 -0.510988 -0.987452

4 6 0 -2.958639 0.218589 -0.338054

5 6 0 -2.160600 -0.451563 0.632027

6 6 0 -2.465909 -1.787971 0.954317

7 6 0 -2.818569 1.644110 -0.685691

8 6 0 -2.160935 2.604813 -0.066254

9 6 0 -1.546642 3.619536 0.487472

10 8 0 -1.147957 0.147226 1.288992

11 1 0 -3.704076 -3.511526 0.587155

12 1 0 -5.052318 -2.368704 -1.189543

13 1 0 -4.573178 -0.002964 -1.741995

14 1 0 -0.412889 0.588828 0.658463

15 1 0 -1.858547 -2.274071 1.713882

16 1 0 -3.389397 1.948738 -1.566377

17 1 0 -2.021094 4.220654 1.263198

18 1 0 -0.522926 3.878836 0.220658

19 55 0 3.266083 -0.339322 -0.136154

20 9 0 0.678995 0.989185 -0.067204

Ts3b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 4.971356 -1.840729 -0.003600

2 6 0 3.682841 -2.393249 0.194328

3 6 0 2.582731 -1.557367 0.225760

4 6 0 2.730536 -0.147514 0.125596

5 6 0 4.052508 0.410893 -0.040050

6 6 0 5.153272 -0.476644 -0.163017

7 6 0 1.601844 0.714053 -0.011067

8 6 0 1.763556 2.085877 -0.107430

9 6 0 1.166056 3.220967 0.285454

10 8 0 4.218872 1.709963 -0.127492

11 1 0 5.835944 -2.499854 -0.037911

12 1 0 3.562505 -3.468035 0.296320

13 1 0 1.578922 -1.959837 0.333911

14 1 0 3.064420 2.163602 -0.386098

15 1 0 6.140477 -0.053884 -0.325950

16 1 0 0.617241 0.249631 -0.220119

17 1 0 0.467514 3.252885 1.123813

18 1 0 1.426905 4.180811 -0.156648

19 55 0 -3.879722 -0.190642 0.007984

20 9 0 -1.032042 -0.573046 -0.342484

Int3b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 4.209083 -1.699845 0.081477

2 6 0 4.827158 -0.423448 -0.162667

3 6 0 4.054226 0.696550 -0.222809

4 6 0 2.615912 0.653425 -0.047214

5 6 0 1.964962 -0.676323 0.159356

6 6 0 2.858889 -1.823106 0.238881

7 6 0 1.927747 1.853109 -0.076195

8 6 0 0.525226 2.084693 0.115836

9 6 0 -0.043801 3.307530 -0.004669

10 8 0 0.724369 -0.828549 0.249631

11 1 0 4.839865 -2.584501 0.137203

12 1 0 5.903755 -0.364484 -0.290580

13 1 0 4.510642 1.668538 -0.397841

14 1 0 -0.100715 1.240251 0.362719

15 1 0 2.393804 -2.788959 0.415734

16 1 0 2.529426 2.744887 -0.262250

17 1 0 -1.121422 3.395547 0.134488

18 1 0 0.542410 4.190285 -0.257246

19 55 0 -2.485839 -0.790047 -0.087075

20 9 0 -2.911997 2.082655 0.273096

Ts4b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -4.618681 -2.072508 0.138712

2 6 0 -3.223296 -2.410668 0.302464

3 6 0 -2.275701 -1.441727 0.200522

4 6 0 -2.631072 -0.050387 -0.057673

5 6 0 -4.067461 0.284524 -0.337866

6 6 0 -5.025611 -0.804998 -0.152713

7 6 0 -1.619584 0.869650 -0.027860

8 6 0 -1.701149 2.336093 -0.131891

9 6 0 -2.026229 3.167309 0.866014

10 8 0 -4.433493 1.402648 -0.740180

11 1 0 -5.360166 -2.862690 0.242340

12 1 0 -2.947935 -3.439617 0.516231

13 1 0 -1.217333 -1.655632 0.334367

14 1 0 -1.350263 2.753921 -1.079454

15 1 0 -6.074876 -0.562001 -0.297105

16 1 0 -0.602005 0.455288 0.093794

17 1 0 -2.352702 2.799124 1.835950

18 1 0 -1.983318 4.245260 0.733894

19 55 0 3.845085 -0.134255 -0.074257

20 9 0 1.001064 -0.537168 0.314145

Int4b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -4.252175 -2.371738 -0.051768

2 6 0 -2.823013 -2.482647 0.063683

3 6 0 -2.057236 -1.355673 0.109622

4 6 0 -2.636393 -0.021260 0.045437

5 6 0 -4.117387 0.094474 -0.089672

6 6 0 -4.867046 -1.155627 -0.122559

7 6 0 -1.710305 1.010441 0.128728

8 6 0 -1.758711 2.459187 0.126803

9 6 0 -2.795683 3.321715 -0.002101

10 8 0 -4.719538 1.188236 -0.175503

11 1 0 -4.850647 -3.280416 -0.083996

12 1 0 -2.364951 -3.466573 0.115904

13 1 0 -0.971602 -1.404490 0.199024

14 1 0 -0.768935 2.900753 0.248175

15 1 0 -5.946442 -1.067233 -0.212306

16 1 0 -0.685090 0.633148 0.225447

17 1 0 -3.812351 2.975277 -0.131053

18 1 0 -2.601064 4.392047 0.023328

19 55 0 3.867259 -0.077870 -0.057627

20 9 0 1.018429 -0.433197 0.326664

Ts5b-CsF

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 -4.683454 -2.043440 -0.363788

2 6 0 -3.504244 -2.440726 0.325184

3 6 0 -2.562534 -1.488439 0.635698

4 6 0 -2.762715 -0.095458 0.368422

5 6 0 -4.047655 0.328064 -0.216939

6 6 0 -4.911663 -0.724980 -0.687840

7 6 0 -1.625648 0.749045 0.306729

8 6 0 -1.720290 2.124007 0.054566

9 6 0 -2.869540 2.828813 0.372477

10 8 0 -4.430241 1.541512 -0.355578

11 1 0 -5.417712 -2.795881 -0.644918

12 1 0 -3.334267 -3.488172 0.557402

13 1 0 -1.614484 -1.778815 1.081860

14 1 0 -0.914477 2.614158 -0.490261

15 1 0 -5.815942 -0.422748 -1.208728

16 1 0 -0.635367 0.270156 0.285569

17 1 0 -3.440531 2.579221 1.255262

18 1 0 -3.043199 3.824378 -0.031193

19 55 0 4.021377 -0.083057 -0.098659

20 9 0 1.178737 -0.443061 0.299869

Product B

Center Atomic Atomic Coordinates (Angstroms)

Number Number Type X Y Z

1 6 0 2.453041 -0.719305 0.034128

2 6 0 2.488809 0.678640 0.095762

3 6 0 1.294560 1.402169 0.054681

4 6 0 0.056334 0.748622 -0.035796

5 6 0 0.043054 -0.662553 -0.079512

6 6 0 1.231048 -1.393766 -0.057264

7 6 0 -1.225483 1.445898 -0.139135

8 6 0 -2.371653 0.758075 -0.014929

9 6 0 -2.325279 -0.715506 0.287099

10 8 0 -1.136366 -1.347405 -0.232475

11 1 0 3.377436 -1.290382 0.060552

12 1 0 3.439201 1.199852 0.169206

13 1 0 1.313567 2.489623 0.084895

14 1 0 -3.344728 1.237067 -0.086813

15 1 0 1.187597 -2.477906 -0.109707

16 1 0 -1.222302 2.517169 -0.327188

17 1 0 -2.370311 -0.896903 1.374756

18 1 0 -3.156114 -1.252926 -0.176113

S1