3rd Central European Symposium on Radiation Oncology

Technological and Biological Sunrise for Radiation Oncology

6-8.10.2016, Ustroń, Poland

Scientific Program

Thursday; 6thOctober 2016

19:00 – Welcome Dinner

Friday; 7th October 2016

9:00 – 9:10Opening Ceremony

9:10– 11:30Radiation Biology and Biomarkers (Part 1)

  • Michael Story (UTSW, Dallas):Challenges to the implementation of predictive biomarkers in radiation oncology [30’]
  • Annett Linge (TUD, Dresden): Biomarkers for individualisation of radiochemotherapy in HNSCC – the German DKTK experience [30’]
  • Katalin Lumniczky (NRIRR, Budapest): Radiochemotherapy induced phenotypical changes in peripheral blood cells of cancer patients [30’]
  • Tomasz Rutkowski(IO, Gliwice): Circulating free HPV DNA as a prognostic marker in patients with HPV-related head and neck cancer treated with radiotherapy or radio-chemotherapy [20’]
  • Piotr Widłak (IO, Gliwice): Inflammation related to acute radiation toxicity is the major factor affecting molecular changes observed in blood of cancer patients treated with radiotherapy [20’]
  • Łukasz Boguszewicz (IO, Gliwice): 1H NMR based metabolomics in monitoring of the head and neck cancer treatment toxicity[10‘]

11:30 – 12:00Coffee Break (and poster viewing)

12:00 – 14:00Particle Therapy (Part 1)

  • Marco Schwarz (Trento Hospital, Trento): How can protons improve radiation oncology? [30’]
  • Roberto Orecchia (CNAO, Pavia):Hadrontherapy with heavy ions: current indications and future perspectives [30’]
  • Thomas Bjork Errickson (Skandion Clinic, Uppsala):One year of clinical practice at the Skandion Clinic - ups and downs [30’]
  • Jiri Kubes (PTC, Prague): Radiochemotherapy with protons [30’]

14:00 – 15:00Lunch (and poster viewing)

15:00 – 18:30Contemporary Radiotherapy and Personalized Treatment (Part 1)

  • Hak Choy (UTSW, Dallas): I-SABR [30’]
  • Rafał Dziadziuszko (GUMed, Gdańsk): Stage III NSCLC – how to individualize definitive radio-chemotherapy? [20’]
  • Krzysztof Składowski(IO, Gliwice): Continuous, chronological monitoring of selected biomarkers can predict the outcome of SCCHN patients treated by RT with or without chemotherapy [20’]
  • Bogusław Maciejewski (IO, Gliwice): Volumetric staging and molecular and image guided radiotherapy for H&N cancer [20’]

16:30 – 17:00Coffee Break (and poster viewing)

  • Rafał Suwiński (IO, Gliwice): Immunotherapy and the abscopal effect of radiotherapy [20’]
  • Rafał Tarnawski (IO, Gliwice): Molecular imaging of breast cancer heterogeneity [20’]
  • Joanna Polańska (SUT, Gliwice): Computer aided segmentation of brain tumour in MRI apparent diffusion coefficient (ADC) maps [20’]
  • Leszek Miszczyk (IO, Gliwice): CyberKnife (CK) radioablation for prostate cancer patients – early results of 400 patients treatment [20’]
  • Małgorzata Wyduba & Wojciech Majewski(IO, Gliwice): The efficacy of palliative radiotherapy for patients with lung cancer: the QoL analysis [10’].

19:30 – Conference Dinner

Saturday; 8th October 2016

9:00 – 11:30Contemporary Radiotherapy and Personalized Treatment (Part 2)

  • Asal Rahimi (UTSW, Dallas): S-PBI (Stereotactic Partial breast Irradiation) [30’]
  • Rafał Tarnawski (IO, Gliwice): Imaging of cervical cancer recurrence (lecture sponsored by Roche)[20’]
  • Daria Handkiewicz-Junak (IO, Gliwice): Consolidation treatment with somatostatin analogues after radiopeptide therapy[10‘]
  • Jolanta Krajewska (IO, Gliwice): Multikinase inhibitors in patients with radioiodine-refractory thyroid cancer – the evaluation of treatment tolerance on the basis of 10-year experience [10’].
  • Agata Celejewska (IO, Gliwice): 10-years of CBS and IORT (INTRABEAM) combined with postoperative EXRT for early breast cancer: incidence and kinetics of local recurrence and distant metastases [10’]
  • Piotr Wojcieszek(IO, Gliwice):High-dose-rate brachytherapy for recurrent prostate cancer – effective tool for the individualized treatment [10’]
  • Aleksandra Napieralska (IO, Gliwice): Craniospinal irradiation – experience of Radiotherapy Department in Gliwice [10’]
  • Dorota Gabryś(IO, Gliwice): Cardiac toxicity after breast cancer patients treatment [10’]
  • Marek Kozicki (LUT, Lodz): Using 3D dosimetry in radiotherapy: DosLab-Poland experience [15’]
  • Krzysztof Ślosarek(IO, Gliwice): Planning, verification and realization of gated VMAT technique[15’]
  • Paulina Leszczyńska (IO, Gliwice):Physical aspect of total marrow irradiation (TMI) [10’]

11:30 – 12:00Coffee Break (and poster viewing)

12:00 – 13.00Particle Therapy (Part 2)

  • Xun Jia (UTSW, Dallas):Fast Monte Carlo simulation on GPU platform for particle therapy [30’]
  • Paweł Olko(IFJ, Kraków): Cooperation towards the first patient on proton scanning beam at the Bronowice Cyclotrone Centre [20’]
  • Tomasz Kajdrowicz(IFJ, Kraków): Collaborative network for particle therapy centers in Italy, Poland, Austria, Czech Republic and Sweden (IPACS) on harmonization of modern proton therapy [10’]

13:00 – 13.40Radiation Biology and Biomarkers (Part 2)

  • Andrzej Gamian (WMU, Wrocław): Unconventional glycation products and their partially protective activity against DNAdamage in cells irradiated with X ray [20’]
  • Andrzej Dworak (CPCM, Zabrze): Nanocarriers of doxorubicin via thermally induced aggregation of its polymeric conjugates [20’]

13.40 – 14:00General conclusions and closing ceremony

14:00 – Lunch

Poster Presentations

  • B. Biesaga,A. Mucha-Małecka, A. Janecka-Widła, S. Szostek, D. Słonina, A. Kowalczyk, K. Halaszka,
    M. Przewoźnik: Prognostic significance of HPV16 presence, its load and genome status in patients with squamous cell carcinoma of head and neck from Cracow area, Poland.
  • M. Ros-Mazurczyk, A. Wojakowska, L. Marczak, K. Polanski, M. Pietrowska, K. Jelonek, I. Dominczyk,
    A. Hajduk, T. Rutkowski, K. Skladowski, P. Widlak: Ionizing radiation affects profile of serum metabolites: increased level of 3-hydroxybutyric acid in serum of cancer patients treated with radiotherapy.
  • Ł. Boguszewicz, A. Hajduk, A. Skorupa, M Ciszek, J. Mrochem-Kwarciak, K. Składowski, M. Sokół: Early treatment response detection in head and neck cancer patients by means of 1H NMR based metabolomic.
  • M. Pietrowska, S. Funk, M. Gawin, Ł. Marczak, P. Widłak, T. Whiteside: Molecular profiling of tumor-derived exosomes in plasma of cancer patients.
  • A. Walaszczyk, M. Pietrowska, A. Wojakowska, A. Abramowicz, P. Rodziewicz, J. Polańska, K. Behrendt, E. Nowicka, R. Tarnawski, P. Widłak: Identification of serum proteins associated with the risk of metastasis of breast cancer patients.
  • K. Szoltysek, P. Janus, A. Walaszczyk, T. Stokowy, P. Widlak: Interplay of NF-kB- and p53-dependent signaling pathways in cellular response to ionizing radiation.
  • E. Wolny-Rokicka, J. Wydmański, A. Tukiendorf: Comparison and estimate of the prognostic value of lipids profiles in 2 groups of patients with prostate cancer in depends on advancement.
  • E. Wolny-Rokicka, J. Wydmański, A. Tukiendorf, P. Mróz, A. Namysł-Kaletka, K. Gramacka,
    J. Lipiński: Correlating parameters platelet counts (PLT) and mean platelet volume (MPV) with tumor and possibility finding his threshold of size.
  • J. Mrochem-Kwarciak, T. Rutkowski, A. Wygoda, R. Deja, Ł. Boguszewicz, P. Widłak, K. Składowski: Osteopontin (OPN) as an instant, predictive biomarker of tumor hypoxia and distant dissemination of HNSCC in patients treated by radiation and chemotherapy.
  • A. Abramowicz, I. Tinhofer-Keilhol, P. Widlak, M. Pietrowska: FaDu-derived radiochemotherapy-resistant clonal cell lines as an experimental model system in exosome research: preliminary study.
  • P. Polanowski, J. Wydmanski, A. Tukiendorf, B. Masłyk: Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer.
  • T. Krzysztofiak, W. Majewski: The efficacy of radical radiotherapy for patients with primarily diagnosed prostate cancer with metastases to regional lymph nodes.
  • H. Grzbiela, M. Stąpór-Fudzińska, R. Tarnawski: The efficacy and safety of stereotactic radiation therapy in patients with multiple intracranial meningiomas - a case report.
  • M. Gawkowska, E. Chmielik, A. d' Amico, W. Bal, E. Nowicka, B. Bobek-Bilewicz, R. Tarnawski: Somatostatin receptor scintigraphic imagining and clinical decision making in advanced esthesioneuroblastoma.
  • E. Nowicka, M. Gawkowska, W. Bal, M. Jarząb, H. Grzbiela, B. Bobek- Billewicz, R. Tarnawski: Unusual presentation of dissemination via cerebrospinal fluid in malignant gliomas-the Centre of Oncology Institute Gliwice experience.
  • E. Nowicka, M. Gawkowska, W. Bal, M. Jarząb, H. Grzbiela, B. Bobek- Billewicz, R. Tarnawski: The feasibility of reirradiation using intensity-modulated radiation in selected patients with recurrent gliomas.
  • K. Dębiec, I. Gorczewska, P. Leszczyńska, K. Gorczewski, W. Leszczyński, M. Kalemba, J. Wydmański: Evaluation of the 18-FDG-PET/CT in radiotherapy planning for unresectable or inoperable gastric cancer patients.
  • B. Jochymek, L. Miszczyk: Half-body irradiation as palliative treatment of patients with multiple painful bone metastases with application tomotherapy.
  • E. Wolny-Rokicka, A. Tukiendorf, J. Wydmański, D. Roszkowska, B. Staniul: Thyroid function after postoperative radiation therapy in patients with breast cancer.
  • D. Księżniak-Baran, M. Stankiewicz, K. Hasse-Lazar, S. Blamek: Linac–based stereotactic radiotherapy as a salvage treatment in patients with Cushing’s disease. Is there a chance for achieving hormonal control?
  • K. Szczepanik, M. Stąpór-Fudzińska, D. Bodusz , B. Jochymek , E. Telka, L. Miszczyk:.Detection of the GoldAnchor™ markers implanted in the liver by the CyberKnife system during the real-time image-guided robotic radiotherapy of patients with liver metastases.
  • Z. Wygoda, D. Handkiewicz-Junak, J. Krajewska, B. Jarząb: Assessment of radiotherapy effects in treatment of anaplastic thyroid carcinoma.
  • W. Osewski, Ł. Dolla, R. Kulik, K. Ślosarek: Dose distribution reconstruction for gated VMAT technique.
  • I. Brąclik, W. Osewski, K. Ślosarek: Dose distribution deformation based on deformable registration.
  • M. Pelak, K. Dębiec: Virtual versus conventional radiotherapy simulation: a single institution experience report.
  • A. Skorupa, M. Kozicki, P. Maras, M. Ciszek, Ł. Boguszewicz, M. Sokół: Application of high field MR micro-imaging in polymer gel dosimetry – preliminary results.
  • A. d'Amico, O. Chrabański, I. Gorczewska, M. Zieliński: Triphasic [18F]-Fluorodeoxyglucose CT-PET in the differential diagnosis of lung nodules and mediastinal lymph nodes: initial results.
  • B. Niewiadomska, A. Bekman, A. Woźnica, Ł. Dolla, S. Blamek: Measurement of dose in the environment of cardiovascular implantable electronic devices (CIEDs) for prostate cancer patients treated by Tomotherapy.
  • S. Blamek, M.Tajstra, E. Gadula-Gacek, D. Gabryś, B. Niewiadomska, A. Bekman, Ł. Dolla,
    M. Gąsior, P. Marczyński: Implantable cardioverters-defibrillators and cardiac resynchronization therapy – defibrillator devices in the setting of helical Tomotherapy: an in vitro study.
  • L. Stolarczyk, J. Gajewski, M. Kłodowska, W. Komenda, D. Krzempek, J. Kunst, N. Mojżeszek, M. Liszka, A. Pędracka, M. Rydygier, B. Sadowski, U. Sowa, P. Olko: Commissioning of spot scanning proton therapy system in Cyclotron Center Bronowice.
  • M. Liszka, M. Rydygier, B. Sadowski, A. Pędracka, W. Komenda, L.Stolarczyk, P. Olko: Feasibility study of patient plan verification method for scanning proton beam at the IFJ in Krakow, Poland.
  • T. Horwacik,B. Michalec, L. Grzanka, E. Durlak, E. Ogrodowicz, T. Nowak: Commissioning of the new ocular proton radiotherapy facility at the CCB IFJ PAN.
  • U. Sowa, T. Nowak, T. Horwacik, T. Kajdrowicz: Application of wedges in the eye line treatment facility in the IFJ CCB Kraków.
  • A. Pędracka, L. Stolarczyk, M. Liszka, W. Komenda, B. Sadowski, K. Skowrońska, P. Olko: Dosimetric verification of treatment planning system in proton spot scanning pencil beam radiotherapy.
  • G. Mierzwińska, B.Michalec, B. Sadowski, M. P.R. Waligórski: Alanine-based QA protocol for dose assessment in ocular melanoma proton radiotherapy.
  • J.Gajewski, M.Bednarczyk, K.Skowrońska, L.Stolarczyk, T.Kajdrowicz, P.Olko: Machine log file analysis as a part of treatment Quality Assurance with proton scanning beams.