Learn more about the pregnancy study!

The purpose of this study is to look at the differences in brain development between babies who are and are not given choline supplements and how genetics may play a role in these differences. Participation in this study begins during pregnancy and lasts until the baby is 18 months old.

What is Choline!!

Choline is an essential nutrient that the body needs to stay healthy. Many foods naturally contain choline including egg yolks, breast milk, soy, cooked beef, chicken, veal, and iceberg lettuce. The FDA requires that infant formula be made from cow’s milk which contains choline. Choline can now be found in some children's vitamins. Choline is a nutrient that supports the mental functioning of the brain and plays a significant role in the development of learning and memory centers of the brain. In addition to improving memory and learning, choline has several other benefits. Choline was found to remove an ingredient in the blood that is associated with an increased risk in heart disease. Also, getting an adequate amount of choline in the diet can prevent birth defects such as spina bifida.

In our study, pregnant mothers will be randomly assigned to two groups. Group 1 will receive choline supplements in pill form and a liquid supplement for their babies. Group 2 will receive placebo (or "fake") supplements also in pill form and a liquid placebo for their babies. The placebo does not contain any choline or any other active ingredients. Once their babies are born, both groups will be asked to give their babies the liquid once a day. After birth, babies are given multiple tests to measure brain development including the P50, the MMN, Developmental Assessments, and a Cheek Swab. Parents of babies are also given multiple tests such as the Clinical Interviews and Blood Draws. Please follow the appropriate links to learn more!

If you are interested in participating in our pregnancy study or just want more information, please contact: Julie Beuler R.N., at (303)724-6205 or send an email to

LINK TO DENVER CHANNEL VIDEO