Appendix 2

Patient characteristics and outcome.

Abbreviations: # - asleep-awake-asleep surgery under 5-ALA fluorescence; * - significant clinical deterioration in early postsurgical period; f – female; m – male; F – frontal; T – temporal; P – parietal; O – occipital lobe; GTR – gross total resection based on contrasting T1-weight imaging; ACA – anterior cerebral artery; CUSA – Cavitron Ultrasonic Surgical Aspirator; KPS – Karnofsky Performance Scale score; UNK – unknown (patient lost to follow-up); NA – not applicable (the patient is still alive at the moment of evaluation).

no. / Sex, age [y] / Histology / Tumour side and lobe / Near eloquent location / Tumour size [cm3] / Preoperative KPS / Postoperative KPS / new focal neurological deficit / Extent of resection / Survival [mo]
1 / m, 49 / gliosarcoma / left T / - / 7.4 / 70 / 60 / - / GTR / 22
2 / f, 57 / GBM / right P / - / 12.6 / 80 / 80 / - / 96% / 18
3 / f, 70 / GBM / right F / +
(motor) / 38.5 / 80 / 40 / +
(ACA injury while attempting to use CUSA under blue light) * / 57% / 7
4 / m, 62 / GBM / right O/P / - / 39.3 / 90 / 80 / - / GTR / 8
5 / f, 66 / GBM / right P / - / 59.7 / 100 / 100 / - / 83% / 10
6 / f, 53 / GBM / left F/T / +
(speech) / 27.1 / 70 / 40 / +
(aphasia, psychomotor activity deterioration) * / GTR / 15
7 / m, 55 / GBM / right F / +
(motor) / 5.9 / 70 / 60 / - / GTR / 17
8 / m, 73 / GBM / right F / +
(speech) / 33.5 / 80 / 70 / - / 61% / 11
9 / f, 58 / GBM / right T / - / 65.7 / 70 / 0
(dead) / +
(vast ischemia) * / 79% / 0
10 / f, 67 / GBM / right T-P / - / 17.9 / 80 / 50 / +
(paresis) / GTR / 14
11 / # m, 61 / GBM / left T / +
(speech) / 28.4 / 90 / 70 / - / 68% / UNK
12 / f, 75 / GBM / right P / +
(motor) / 26.7 / 80 / 70 / - / 72% / 9
13 / f, 34 / AA / left T / +
(speech) / 10.8 / 100 / 90 / - / 70% / NA
14 / f, 59 / GBM / left F
(right-hemisphere dominance) / - / 23.2 / 100 / 80 / - / 64% / 10
15 / f, 53 / GBM / right P / - / 11.1 / 70 / 40 / +
(paresis) * / GTR / UNK
16 / f, 41 / GBM / left F / - / 33.0 / 70 / 60 / - / 87% / NA
17 / f, 62 / GBM / left P / - / 35.3 / 80 / 80 / - / GTR / 8
18 / m, 74 / GBM / left F/T / +
(speech) / 28.0 / 70 / 30 / +
(aphasia, ischemia) * / GTR / NA
19 / m, 57 / GBM / right O / +
(visual) / 42.6 / 80 / 80 / - / GTR / NA
20 / m, 63 / gliosarcoma / left T / +
(speech) / 25.9 / 90 / 70 / - / 62% / NA
21 / f, 68 / GBM / right F / - / 42.2 / 70 / 70 / - / 75% / NA