Supplemental Table 4: TARA Class B genes which were among the 276 immune related genes differentially expressed by MSCs co-cultured with activatedTIL. The fold change in expression of these genes in MSCs co-cultured with melanoma-activated TIL compared to control MSCs are shown.

MSC(+TIL+M38) vs. MSC control
Gene Symbol / Fold-Change / p-value
CCL2 / 24.4 / 6E-11
CCL20 / 1.3 / 1E-02
CCL4 / 2.4 / 3E-03
CCL5 / 20.9 / 2E-10
CCL8 / 44.3 / 4E-21
CCR1 / 2.5 / 2E-04
CCR7 / 1.8 / 2E-03
CD14 / 3.7 / 4E-08
CD163L1 / 1.8 / 3E-07
CD164 / 1.2 / 1E-02
CD2 / 4.3 / 5E-04
CD200 / 2.0 / 8E-03
CD247 / 1.8 / 4E-03
CD274 / 19.8 / 1E-14
CD2AP / 1.7 / 1E-07
CD33 / 1.5 / 7E-04
CD38 / 6.4 / 6E-04
CD40 / 9.9 / 2E-18
CD44 / 2.1 / 1E-05
CD47 / 3.2 / 1E-11
CD52 / 1.5 / 8E-03
CD68 / 1.4 / 2E-04
CD72 / 2.4 / 8E-04
CD74 / 101.3 / 4E-20
CD83 / 2.3 / 3E-03
CD8A / 3.3 / 6E-04
CD97 / 1.6 / 1E-06
CXCL1 / 7.7 / 3E-03
CXCL10 / 57.5 / 2E-14
CXCL11 / 64.7 / 1E-14
CXCL16 / 5.0 / 8E-12
CXCL2 / 10.5 / 4E-09
CXCL3 / 4.7 / 9E-05
CXCL9 / 183.2 / 2E-23
CXCR4 / 1.4 / 2E-03
HLA-A / 6.9 / 5E-14
HLA-B / 21.5 / 2E-14
HLA-C / 6.6 / 2E-13
HLA-DMA / 17.1 / 1E-24
HLA-DMB / 174.5 / 1E-20
HLA-DOA / 214.6 / 4E-25
HLA-DOB / 3.4 / 9E-13
HLA-DPA1 / 16.5 / 3E-31
HLA-DPB1 / 7.0 / 2E-22
HLA-DQA1 / 40.7 / 1E-15
HLA-DQA2 / 47.3 / 6E-19
HLA-DQB1 / 72.7 / 2E-23
HLA-DQB2 / 12.8 / 3E-17
HLA-DRA / 86.6 / 6E-23
HLA-DRB3 / 5.1 / 3E-19
HLA-DRB4 / 95.9 / 1E-23
HLA-DRB5 / 99.5 / 2E-22
HLA-E / 5.3 / 4E-16
HLA-F / 28.9 / 2E-17
HLA-G / 8.3 / 6E-14
HLA-J / 7.5 / 3E-13
ICAM1 / 34.6 / 5E-13
ICAM2 / 1.7 / 1E-05
IDO1 / 114.7 / 3E-29
IFI16 / 3.0 / 1E-14
IFI27 / 14.8 / 7E-17
IFI30 / 7.6 / 1E-17
IFI35 / 6.2 / 5E-18
IFI44 / 9.9 / 8E-15
IFI44L / 28.7 / 5E-18
IFI6 / 14.5 / 2E-18
IFIH1 / 26.0 / 2E-18
IFIT2 / 83.6 / 4E-12
IFIT3 / 17.1 / 4E-22
IFIT5 / 2.6 / 6E-21
IFITM1 / 24.7 / 8E-23
IFITM2 / 2.2 / 2E-11
IFITM3 / 3.6 / 1E-15
IFNAR1 / 1.3 / 6E-04
IFNAR2 / 1.4 / 1E-04
IFNGR1 / 1.5 / 8E-04
IL10RA / 1.2 / 4E-03
IL10RB / 1.3 / 1E-07
IL12RB1 / 1.6 / 8E-03
IL15 / 6.8 / 2E-18
IL17RA / 2.2 / 1E-07
IL18BP / 3.8 / 5E-15
IL18R1 / 19.5 / 4E-12
IL18RAP / 7.1 / 8E-11
IL1B / 6.4 / 1E-04
IL1R1 / 1.7 / 1E-03
IL1RL1 / 13.4 / 4E-08
IL1RN / 1.7 / 2E-05
IL2RB / 2.3 / 3E-03
IL32 / 2.9 / 2E-03
IL3RA / 6.7 / 5E-10
IL4I1 / 7.2 / 1E-09
IL4R / 1.5 / 4E-04
IL6 / 2.7 / 2E-08
IL6ST / 2.6 / 1E-09
IL7 / 4.7 / 1E-08
IL7R / 3.4 / 5E-04
IRAK2 / 1.7 / 5E-03
IRAK3 / 5.2 / 4E-06
IRAK4 / 1.3 / 4E-03
IRF1 / 11.2 / 1E-17
IRF2 / 3.6 / 1E-11
IRF5 / 1.3 / 1E-02
IRF8 / 7.1 / 2E-06
IRF9 / 2.5 / 2E-16
ITK / 21.8 / 3E-14
JAK2 / 6.8 / 8E-19
JAK3 / 3.5 / 5E-09
LGALS3BP / 1.7 / 3E-07
LGALS8 / 1.6 / 6E-04
LGALS9 / 8.8 / 5E-10
LGALS9C / 7.0 / 2E-15
NFKB1 / 1.5 / 5E-05
NFKB2 / 1.6 / 4E-05
NFKBIA / 3.0 / 4E-08
NFKBIB / 1.4 / 1E-03
NFKBIE / 1.9 / 1E-04
NFKBIZ / 2.2 / 8E-07
TNFAIP2 / 3.3 / 2E-10
TNFAIP3 / 2.3 / 9E-03
TNFRSF1B / 2.2 / 1E-07
TNFSF10 / 48.0 / 8E-15
TNFSF12 / 1.6 / 3E-08
TNFSF13B / 33.0 / 8E-24
VCAM1 / 2.5 / 4E-05
VEGFC / 2.1 / 2E-07
IREB2 / -1.1 / 2E-03
CD4 / -1.2 / 2E-04
MMP19 / -1.3 / 9E-03
CD248 / -1.5 / 7E-05
CD86 / -1.6 / 2E-05
CXCL12 / -1.6 / 2E-03
IL21R / -1.7 / 6E-03
ICAM3 / -1.8 / 5E-07
FGF7 / -3.5 / 7E-07