9862 / Neg. / Neg. / Mutated / Del13q / A / untreated / K
9879 / Pos. / n.d. / Unmutated / n.d. / B / untreated / K, T, M
9906 / Neg. / Neg. / Mutated / Del13q / B / untreated / K
9907 / Pos. / Pos. / Unmutated / normal / A / untreated / K
9895 / Pos. / neg / Mutated / n.d. / C / untreated / T, M
9877 / Neg. / pos / Mutated / del13q / A / untreated / T, M
9878 / Pos. / Pos / n.d. / del11q, tri12 / C / Multiple regimens / T, M
9896 / Neg. / Neg. / Mutated / Del13q / B / untreated / T, M
9897 / Neg / Pos. / Unmutated / n.d. / C / FC / T, M
7929 / Pos. / Pos. / Unmutated / Trisomy 12 / C / Chlorambucil / K, T
(Leukapheresis)
8778
8659 / -/+
ambigous / Neg. / Unmutated / A / untreated / O, T
8799 / Neg. / n.d. / n.d. / n.d. / A / untreated / O, T
8804 / Pos / Neg. / n.d. / n.d. / C / untreated / T
8295 / Pos / Neg. / Mutated / n.d. / B / untreated / T
8337 / Pos / Neg. / Unmutated / n.d. / C / FC / T
8385 / Pos / Neg. / Unmutated / n.d. / A / FCR / T
8386 / Neg. / Neg. / Unmutated / normal / A / Chlorambucil / T
8392 / Neg. / Neg. / Mutated / normal / A / Chlorambucil / T
8393 / Pos. / Neg. / Mutated / normal / B / naive / T
Supplementary Table S1
Legend for applied steps:
O - treatment of live cells with drug, followed by Kinobeads extraction
K - Kinobeads profiling of native sample
M - Microenvironment assay
T - Toxicity assessment