FINAL SCIENTIFIC PROGRAMME
Tuesday, 22 November 2011
09:00 Registration and Coffee
10:00 - 10:30 Opening Session Senate Hall
Chairperson: Adee Matan, Israel
WELCOME
Rivka Carmi, President, Ben-Gurion University of the Negev
Matthew Gould, British Ambassador to Israel
10:30 - 13:00 Plenary Session Senate Hall
HIGHLIGHTS OF REGENERATIVE MEDICINE
Chairpersons: Lord Naren Patel, UK
Benjamin Geiger, Israel
10:30 HUMAN EMBRYONIC STEM CELLS – FROM BENCH TO BEDSIDE
Benjamin E. Reubinoff, Hadassah University Medical Center,
Jerusalem, Israel
11:00 V BIO-INSPIRED MATERIALS FOR REGENERATIVE MEDICINE
Smadar Cohen, Ben-Gurion University of the Negev, Beer Sheva,
Israel
11:30 Coffee Break
12:00 TISSUE ENGINEERING: AN ENABLING TECHNOLOGY
Dame Julia Polak, Imperial College London, UK
Tuesday, 22 November 2011 (cont.)
12:30 EPICARDIUM-DERIVED CARDIAC REPAIR
Paul R. Riley, University College London, UK
13:00 Lunch
14:00 - 18:00 Session 2A Barkan Hall
TRANSLATIONAL CELL THERAPY IMMUNOLOGY & MANUFACTURE
Chairpersons: Tamir Ben-Hur, Israel
Julie Daniels, UK
14:00 STEM CELL THERAPIES FOR SKELETAL DISORDERS
Dan Gazit, The Hebrew University of Jerusalem, Israel
14:30 HUMAN PLURIPOTENT STEM CELLS: IMPLICATIONS FOR BASIC
AND TRANSLATIONAL CARDIAC RESEARCH
Lior Gepstein, Technion, Israel Institute of Technology, Haifa, Israel
15:00 STEM CELL THERAPY IN ALS
Daniel Offen, Tel Aviv University, Tel Aviv, Israel
15:30 STEM CELL THERAPY FOR BLINDING CORNEAL DISEASE
Julie Daniels, UCL Institute of Ophthalmology, London, UK
16:00 Coffee Break
16:30 THE CHONDROCYTE: A FLEXIBLE TOOL FOR RECONSTRUCTION
James B. Richardson, RJAH, NHS Trust, UK
17:00 TISSUE ENGINEERING CHALLENGES IN ORTHOPAEDIC SURGERY
Andrew McCaskie, Newcastle University, UK
17:30 Poster presentations
18:00 Buses return to hotel
19:00 Depart for Bedouin Style Dinner - one bus from the university and two buses from the hotel
Tuesday, 22 November 2011 (cont.)
14:00 - 18:00 Session 2B Oren Hall
STEM CELL / TRANSPLANTATION IMMUNOLOGY & MANUFACTURE
Chairpersons: Paul Fairchild, UK
Yair Reisner, Israel
14:00 MECHANISMS OF PANCREATIC BETA CELL REGENERATION
Yuval Dor, The Hebrew University of Jerusalem, Israel
14:30 ALPHA-1 ANTITRYPSIN PROTECTS CELL TRANSPLANTS,
FACILITATES ANGIOGENESIS AND ENHANCES GRAFT-SPECIFIC
IMMUNE TOLERANCE IN VIVO
Eli Lewis, Ben-Gurion University of the Negev, Beer Sheva, Israel
15:00 PIG EMBRYONIC PANCREATIC TISSUE FOR CORRECTION OF
DIABETES
Yair Reisner, Weizmann Institute of Science, Rehovot, Israel
15:30 DENDRITIC CELLS AND PLURIPOTENCY: UNEXPECTED
ALLIES IN THE PURSUIT OF IMMUNOTHERAPY
Paul Fairchild, University of Oxford, Oxford, UK
16:00 Coffee Break
16:30 MANUFACTURE AND SUPPLY OF A CELLULARISED BIOCOMPATIBLE POLYMER SCAFFOLD AS AN ADVANCED THERAPY MEDICINAL PRODUCT FOR TRACHAEAL REPLACEMENT
Mark Lowdell, University College London, UK
17:00 CELL THERAPY TO PROMOTE TRANSPLANTATION TOLERANCE: A WINNING STRATEGY?
Giovana Lombardi, King’s College London, London, UK
17:30 Poster presentations
18:00 Buses return to hotel
19:00 Depart for Bedouin Style Dinner - one bus from the university and two buses from the hotel
Wednesday, 23 November 2011
08:15 - 09:00 Optional Session A Barkan Hall
QUESTIONS AND ANSWERS
Questions and answers related to the BIRAX Regenerative Medicine
Initiative Call for Proposals, British Council, Israel
08:15 - 09:00 Optional Session B Oren Hall
PARTY PITCH YOUR POST-DOC
Science Communication / Networking for early career researchers
Facilitated by Aarathi Prasad, freelance science journalist, author and broadcaster, Natural Resources / Science Communication Advisor, British Council, UK
09:00 - 12:30 Session 3A Barkan Hall
STEM CELL DERIVATION, GENOMICS, GENOMICS REPROGRAMMING & EPIGENETICS
Chairpersons: Nissim Benvenisty, Israel
Paul De Sousa, UK
09:00 THE ROLE OF PLURIPOTENT STEM CELLS IN MODELING HUMAN DISORDERS
Nissim Benvenisty, The Hebrew University of Jerusalem, Israel
09:30 UNDERSTANDING THE IDENTITY AND STABILITY OF
PLURIPOTENT CELL STATES
Jacob Hanna, Weizmann Institute of Science, Rehovot, Israel
10:00 THE ROLE MIRNAA PLAY AS DEVELOPMENTAL SWITCHES
Eran Hornstein, Weizmann Institute of Science, Rehovot, Israel
10:30 DEVELOPING SCALABLE AUTOMATION OF HUMAN PLURIPOTENT STEM CELL (HPSC) EXPANSION AND DIFFERENTIATION FOR MULTIPLE SCREENING APPLICATIONS
Lorraine Young, University of Nottingham, UK
11:00 Coffee Break
11:30 PLURIOPTENT STEM CELL TRANSLATION: BASIC AND APPLIED
SCIENCE SUPPORTING HUMAN EMBRYONIC STEM CELLS IN
REGENERATIVE MEDICINE
Paul De Sousa, University of Edinburgh, UK
12:00 MESODERM DIFFERENTIATION IN PLURIPOTENT MAMMALIAN
STEM CELLS
Roger Pedersen, University of Cambridge, UK
12:30 Lunch
Wednesday, 23 November 2011 (cont.)
09:00 - 12:30 Session 3B Oren Hall
BIOMATERIALS, TISSUE ENGINEERING
Chairpersons: Hanna Rapaport, Israel
Kevin Shakesheff, UK
09:00 NANOTECHNOLOGICAL STRATEGIES FOR MENDING BROKEN HEARTS
Tal Dvir, Tel Aviv University, Israel
09:30 NATURAL EXTRACELLULAR MATRIX PLATFORMS TOWARDS ENGINEERING OF THICK CARDIAC CONSTRUCTS
Marcelle Machluf, Technion, Israel Institute of Technology, Haifa, Israel
10:00 SELF ASSEMBLED ACIDIC PEPTIDES; FROM DESIGN TO
BIOMATERIALS FOR BONE TISSUE REGENERATION
Hanna Rapaport, Ben-Gurion University of the Negev, Beer Sheva, Israel
10:30 NEW MATERIALS-BASED STRATEGIES FOR REGENERATIVE MEDICINE
Molly Stevens, Imperial College London, UK
11:00 Coffee Break
11:30 CONTROLLING CELL BEHAVIOUR USING 3D ARCHITECTURES
Kevin Shakesheff, University of Nottingham, UK
12:00 CONTROLLING CELLS FOR USE IN CLINICAL THERAPIES USING MAGNETIC NANOPARTICLES
Alicia El Haj, Keele University, UK
12:30 Lunch
Wednesday, 23 November 2011 (cont.)
13:30 - 16:30 Session 4A Barkan Hall
STEM CELL BIOLOGY: LESSONS FROM DEVELOPMENT
Chairpersons: Sue Kimber, UK
Dov Zipori, Israel
13:30 A REGULATORY NETWORK OF TISSUE-SPECIFIC MODIFIERS UNDERLIES THE ETIOLOGY OF DIGEORGE DELETION SYNDROME
Eldad Tzahor, Weizmann Institute of Science, Rehovot, Israel
14:00 TRANSLATING HUMAN KIDNEY DEVELOPMENT TO CELL
THERAPY OF RENAL INJURY AND TARGETED THERAPY OF
RENAL CANCER
Benjamin Dekel, Sheba Medical Center, Tel Hashomer, Israel
14:30 MESENCHYMAL STROMAL CELLS AS A PARADIGM OF THE STEM STATE: PLASTIC NATURE ENTAILING HETEROGENEITY AND CAPACITY TO DE-DIFFERENTIATE
Dov Zipori, Weizmann Institute of Science, Rehovot, Israel
15:00 REGULATION OF NEURAL STEM CELLS BY INTEGRINS AND
EXTRACELLULAR MATRIX
Charles ffrench-Constant, University of Edinburgh, UK
15:30 TWINNING: THE ULTIMATE REGENERATION
Claudio D. Stern, University College London, UK
16:00 GENERATION OF CHONDROGENIC CELLS FROM HUMAN PLURIPOTENT CELLS
Sue Kimber, University of Manchester, UK
16:30 Coffee Break
Wednesday, 23 November 2011 (cont.)
13:30 - 16:30 Session 4B Oren Hall
GENE THERAPY AND GENE-MODIFIED CELLS
Chairpersons: Andrew Baker, UK
Tamir Ben-Hur, Israel
13:30 DEVELOPMENT OF BETA-CELL REPLACEMENT THERAPY FOR DIABETES
Shimon Efrat, Tel Aviv University, Israel
14:00 USE OF AUTOLOGOUS VENOUS ENDOTHEIAL AND SMOOTH MUSCLE CELLS MODIFIED BY GENE TRANSFER FOR INDUCTION OF ARTERIOGENESIS
Moshe Flugelman, Technion, Israel Institute of Technology, Haifa, Israel
14:30 DIRECT REPROGRAMMING OF HUMAN ADULT CELLS INTO
INSULIN PRODUCING CELLS; CELL REPLACEMENT THERAPY FOR DIABETIC PATIENTS
Sarah Ferber, Sheba Medical Center, Tel Hashomer, Israel
15:00 GENE THERAPY FOR IMMUNODEFICIENCY
Adrian Thrasher, University College London, UK
15:30 Modifying vein grafts by gene therapy
Andrew Baker, University of Glasgow, UK
16:00 CELL THERAPY FOR MULTIPLE SCLEROSIS
Tamir Ben-Hur, Hadassah Medical Center, Jerusalem, Israel
16:30 Coffee Break
17:00 - 19:00 Closing Plenary Discussion Senate Hall
POSTER AWARDS
Prizes will be awarded for the 3 best posters by Simon Kay, Director, British Council Israel and Adee Matan, Science and Innovation Attache, British Embassy
REGENERATIVE MEDICINE: THE ROAD AHEAD
Moderators: Chris Mason, UK
Smadar Cohen, Israel
Panelists: Martin Birchall, UK
Anthony Hollander, UK
Joseph Itskovitz-Eldor, Israel
Michel Revel, Israel
Yosef Shiloh, Israel
Glyn Stacey, UK
CLOSING REMARKS
Simon Kay, Director, British Council Israel
19:30 Return transfer to the hotel