Skeletal System: 206 bones- bones composed of osseous tissue (a type of connective tissue)
joints- where 2 bones meet
ligaments - connects bone to bone (strong, tough connective tissue)
cartilage- strong, flexible connective tissue
locations 1. articulations- movable joints (provides smooth surface on jt.)
2. need of flexibility: tip of nose
external ear
larynx (voice box)
rib attachment
2 subdivisions: Axial Skeleton: bones that form the longitudinal axis of the body
Appendicular Skeleton: bones of the limbs and girdles
I. Bones: An Overview
A. Functions of Bones
1. Supportive internal framework
bones form internal framework that supports and anchors all soft organs
bones of legs support body torso when standing erect
rib cage supports the thoracic wall
2. Protection of soft body organs
fused bones of skull protect brain
vertebrae protect the spinal cord
rib cage protects the thoracic organs (heart & lungs)
3. Movement using bones as levers
skeletal muscles attached to bones by tendons
bones used as levers to move body and its parts
4. Storage of calcium and phosphorus, etc
fat is stored in the internal cavities of bones
minerals stored in bones......
calcium - needed for 1. neural transmission
2. muscle contraction
3. blood clot formation
hormones control mvmt of Ca to & from bones and blood
phosphorus- part of ATP, nucleic acids, and proteins
5. Hematopoiesis- blood cell formation in red marrow cavities of certain bones
location: usually spongy bone
Red Bone Marrow
Mature and Immature RBC’s, WBC’s, and stem cells
Blood cell formation
Found mainly in flat bones, hips, sternum, skull, ribs, vertebrae, scapula
Yellow Bone Marrow
Fat cells
Energy reserves
Found in the diaphysis of long bones
Classification of Bones
1. Long Bones
Length of the bone exceeds its width
- Humerus, femur
2. Short Bones
Cubelike with roughly equal lengths and widths
- Carpals, tarsals
3. Flat Bones
Thin, flattened, with slight curvature
Compact bones with spongy layer
- Sternum, ribs
4. Irregular Bones
Variety of shapes
Usually connected to other bones
- Vertebrae, pelvis
5. Sesamoid Bones
Short bones that form within tendons
- Patella (the only named sesamoid bone in the body)
- 2 bones under the 1st MP joint
Composition of Bone
- Specialized cells
- Matrix consisting of extracellular protein fibers and a ground substance
- Specialized Connective Tissue
Bone Composition:
2/3 the weight of bone is Calcium Phosphate - Ca3(PO4)2
Calcium Phosphate interacts with calcium hydroxide to form Hydroxyapatite
- Makes bone hard and resistant to crushing
Mineral amount in bone as a % of the total amount in the body:
Calcium 99% Potassium 4% Sodium 35%
Magnesium 50% Carbonate 80% Phosphate 88%
1/3 is collagen fibers – gives bone strength and resilience
- Dense fibrous connective tissue
2% is cells
Collagen fibers form an organic framework on which hydroxyapatite crystals form
Bone Cells
Osteoblasts: make the proteins that form the organic matrix of bone and control the mineralization
- Become surrounded with matrix à osteocytes
Osteocytes: live inside the bone, have long branches which allow communication with each other
Osteoclasts: Resorb bone by secreting acids and enzymes
- Undergo apoptosis (programmed cell death)
- Are found in shallow depressions (Howship’s Lacunae) that they have eroded into the matrix
Bone constantly undergoes remodeling (reshaping) to adapt to changing biochemical forces and to remove old, microdamaged bone
Structure of a Long Bone
Epiphysis – the two ends of the bone that are covered by articular cartilage
Diaphysis – the shaft of the bone
Metaphysis – lies between the diaphysis and epiphysis, and is a conical region adjacent to the area where active bone growth occurs
Medullary Cavity (Marrow Cavity) – the central portion of the shaft of many bones, it contains stem cells that produce blood cells
Periosteum – a thin fibrous connective tissue sheath that surrounds the shaft of a bone
Articular Cartilage – hyaline cartilage found on the articular surface of bones
Endosteum - a thin vascular membrane of connective tissue that lines the surface of the bony tissue that forms the medullary cavity of long bone
Compact Bone – dense bone that forms the outer layer of a bone
Spongy Bone – cancellous bone that contains a meshwork of thin trabeculae or spicules of bone tissue, and is found in the epiphysis of long bones
The Osteon
The Osteon: the functional unit of cortical bone
Aka: Haversian System
- Consists of concentric layers of bony matrix surrounding a central
Haversian Canal
- 1691 by English anatomist Clopton Havers
Haversian Canal: contains the blood vessels and nerve supply to the bone
Volkman’s Canals: (Perforating Canals) Lateral branches that carry blood
vessels from one osteon to another
Osteocytes: bone cells
Lucanae: tiny, bony chambers
Canaliculi: cellular processes used to transport nutrients and waste to and
from nearby cells
· Many osteons cemented together from compact bone
· The ECM of bone tissue is largely collagen and inorganic salts
Nutrient Foramen: The external opening for the entrance of blood vessels in a bone
*Spongy bone is not arranged in Osteons
Spongy Bone
- Composed of osteocytes and
layers of extracellular matrix but
not arranged around a central canal
trabeculae – small needle-like pieces
of bone
Feedback Control for Blood Calcium
Refer to diagram and textbook page 204-205
*** STUDY THE POWERPOINT NOTES ON BONE GROWTH AND DEVELOPMENT
Bones of the Adult Skeleton
Bones of the Skull
1. Frontal - anterior portion above eyes
2. Parietal - one on each side of the skull, just behind frontal bone
3. Occipital - forms the back of the skull and base of the cranium
4. Temporal - forms parts of the sides and base of cranium
5. Sphenoid - wedged between several other bones in anterior portion of the cranium
6. Maxilla - forms upper jaws
7. Mandible - lower jaws, only moveable bone of the skull
Sutures
1. Coronal - between frontal and parietal bones
2. Lambdoidal - between occipital and parietal bones
3. Squamosal - between temporal and parietal bones
4. Sagittal - between parietal bones
Fontanels - "soft spots" of an infant's skull,
- anterior fontanel, posterior fontanel, sphenoid fontanel, mastoid fontanel
Vertebral Column (strong, flexible rod )
26vertebrae (5 sections)
7 cervical vertebrae Atlas C1 Axis C2
12 thoracic vertebrae
5 lumbar vertebrae
sacrum(fusion of5 sacral vertebrae)
Coccyx(fusion of4 coccygeal vertebra
The Rest of the Bones
Ribs - Thoracic Cage, 12 pairs
- True Ribs - first seven pairs, attach directly to STERNUM by costal cartilage
(Vertebralsternal)
- False Ribs - last five pairs (Vertebralchondral)
- Floating ribs - last two pairs (Vertebral)
Pectoral Girdle: Shoulder. Two clavicles (collar bones) and two scapula (shoulder blade)
Arms: Upper arm - humerus. Lower arm - radius and ulna.
Wrist - 8 small bones called carpals
Fingers - Metacarpals, Phalanges
Pelvic Girdle: Hips. Two large bones called COXAL BONES
Ileum, Ischium, Pubis
Acetabulum
Legs: Upper leg (thigh) - FEMUR. Lower leg - tibia & fibula.
Ankle and Upper foot - 7 bones called TARSALS, `- Talus, Calcaneous, Navicular, 3 Cuneiforms, Cuboid
Largest is the heel bone called the CALCANEOUS
Toes - Metatarsals, Phalanges