Key Publications for TDDT Nanopharmaceutics Group Page

Key publications for TDDT Nanopharmaceutics group page

Hoskins, C., Kong Thoo Lin, P., Tetley, L., Cheng,W.P. (2012). The Use of Nano Polymeric Self-Assemblies Based on Novel Amphiphilic Polymers for Oral Hydrophobic Drug Delivery. Pharm Res. 29, 782-794.

Guo, J.F., Cheng, W.P., Gu, J.X., Ding, C.X., Qu, X.Z., Yang, Z.Z., O’Driscoll, C. (2012). Systemic delivery of therapeutic small interference RNAs using a pH-triggered amphiphilic poly-L-lysine nanocarrier to suppress prostate cancer growth in mice.Eur J Pharm Sci. 45, 521-532.

Hoskins, C., Wang, L.Y., Cheng, W.P.Cuschieri, A. (2012). Dilemmas in the reliable estimation of the in-vitro cell viability in magnetic nanoparticle engineering: which tests and what protocols? Nanoscale Research Letters. 7, 77-89.

Hoskins, C., Kong Thoo Lin, P., Cheng, W.P. (2012).A review on comb-shaped amphiphilic polymers for hydrophobic drug solubilisation.Therapeutic Delivery. 3, 59-79.

Hoskins, C., Kong Thoo Lin, P., Tetley, L., Cheng, W.P. (2012). Novel fluorescent amphiphilicpoly(allylamine) and their supramacromolecular self-assemblies in aqueous media. Polymers for Advanced Technologies.23,710-719.

Khan, A., Traynor, M., Cheng, W.P. (2012).In Vitro Toxicity Testing of Polymer Based Nano-structures.UKICRS Newsletter,(in print).

Garrett, N., Lalatsa, A., Begley, B.J., Mihoreanu, L., Schätzlein, A., Uchegbu, I.F., Mojer, J. (2012). Exploring the uptake mechanisms of oral nanomedicines using multimodal nonlinear optical microscopy. J Biophotonics, 5, 458-68 (DOI:10.1002/jbio.201200006).

Lalatsa, A., Lee, V.,Schätchlein, A.G., Zloh, M., Malkinson, J.,Uchegbu, I.F. (2012). A Prodrug Nanoparticle Approach for the Oral Delivery of Hydrophilic Peptides to the Brain. Molecular Pharm, 9, 1665-80 (DOI:10.1021/mp300009u).

Lalatsa, A., Garrett, N., Ferrarelli, T., Mojer, J., Schätzlein, A., Uchegbu, I.F. (2012).Delivery of Peptides to the Blood and Brain after Oral Uptake of Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles.Molecular Pharm, 9, 1764-74 ( DOI:10.1021/mp300068j)

Lalatsa, A., Schätzlein, A.G., Mazza, M., ThiBich Le, H., Uchegbu, I.F. (2012).Amphiphilic Poly (L-amino acids) – New Materials for Drug Delivery.J. Control. Release, 161, 523-36 (DOI:10.1016/j.jconrel.2012.04.046).

Gu,J-X., Cheng, W.P., Hoskins, C., Kong Thoo Lin, P., Zhao,L., Qu, X., Yang, Z. (2011).Nano self-assemblies based on cholate grafted poly-L-lysine enhanced the solubility of sterol-like drugs. J Microencapsulation. 28, 752 - 762.

Thompson, C., Cheng, W.P., Gadad, P., Skene, K., Smith, M.,Smith, G.,McKinnon, A.,Knott, R. (2011). Uptake and transport of Novel Amphiphilic Polyelectrolyte-insulin nanocomplexes by Caco-2 cells-towards oral insulin. Pharm Res 28, 886–896.

Garrett, N., Lalatsa, A., Begley, B.J., Mihoreanu, L., Schätzlein, A., Uchegbu, I.F., Mojer, J. (2011). Label-free Imaging of Polymer Nanomedicines using Coherent Anti-Stokes Raman Scattering Microscopy. J Raman Spectrosc, 43 (5): 681-88 (DOI:10.1002/jrs.3170).

Mojer, J., Garrett, N., Begley, B.J., Mihoreanu, L., Lalatsa, A., Losano, M.V.Mazza, M., Schätzlein, A., Uchegbu, I.F. (2011). Imaging Cortical Vasculature with Stimulated Raman Scattering and Two-Photon Photothermal Lensing Microscopy. J Raman Spectrosc, 43(5): 668-74 (DOI:10.1002/jrs.3156).

Hoskins, C., Ouaissi, M.,Costa Lima, S., Cheng W.P., Loureirio,I., Mas, E., Lombardo, D., Cordeiro, A., Ouaissi, A., Kong Thoo Lin, P. (2010).The study of in Vitro and in Vivo Anticancer cancer Activity of a Novel nano-sized Formulation against Pancreatic Cancer. Pharm Res. 27, 2694-2703.

Cheng, W.P., Thompson, C., Ryan, W.M., Aguirre, T., Tetley, L., Brayden,.D.J (2010).In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte-salmon calcitonin nanocomplexes. J Control Rel. 147, 289-297.