AppendixB. Statistical significance tests comparing the rates of change in opioid-related stays between pairs of time periods (pre-transition vs. ICD transition; and pre-transition vs. post-transition).
Table B.1Inpatient stays with any opioid-related diagnosis by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 48,412 / 5,080 / 19,455 / 16,677 / 7,196
2015 Q2 / 50,846 / 5,094 / 21,130 / 17,385 / 7,235
2015 Q3 / 53,422 / 5,392 / 22,392 / 18,107 / 7,525
2015 Q4 / 60,936 / 5,467 / 22,844 / 21,281 / 11,338
2016 Q1 / 60,985 / 5,322 / 22,672 / 21,471 / 11,518
2016 Q2 / 62,871 / 5,196 / 24,101 / 21,998 / 11,574
2016 Q3 / 65,282 / 5,163 / 25,554 / 22,601 / 11,957
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / 4.338 / -1.712 / -9.434 / 5.806 / 17.925
p-value / 0.000 / 0.087 / 0.000 / 0.000 / 0.000
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / -4.031 / -3.295 / -1.701 / -2.279 / -0.358
p-value / 0.000 / 0.001 / 0.089 / 0.023 / 0.720
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.2Inpatient stays with any opioid-related diagnosis by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 48,412 / 5,080 / 19,455 / 16,677 / 7,196
2015 Q2 / 50,846 / 5,094 / 21,130 / 17,385 / 7,235
2015 Q3 / 53,422 / 5,392 / 22,392 / 18,107 / 7,525
2015 Q4 / 60,936 / 5,467 / 22,844 / 21,281 / 11,338
2016 Q1 / 60,985 / 5,322 / 22,672 / 21,471 / 11,518
2016 Q2 / 62,871 / 5,196 / 24,101 / 21,998 / 11,574
2016 Q3 / 65,282 / 5,163 / 25,554 / 22,601 / 11,957
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / 4.338 / -1.712 / -9.434 / 5.806 / 17.925
p-value / 0.000 / 0.087 / 0.000 / 0.000 / 0.000
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / -4.031 / -3.295 / -1.701 / -2.279 / -0.358
p-value / 0.000 / 0.001 / 0.089 / 0.023 / 0.720
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.3Inpatient stays with a diagnosis of opioid abuse by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 11,209 / 1,529 / 5,327 / 3,913 / 439
2015 Q2 / 12,267 / 1,599 / 6,045 / 4,099 / 523
2015 Q3 / 13,229 / 1,715 / 6,592 / 4,400 / 521
2015 Q4 / 10,441 / 1,306 / 5,231 / 3,498 / 406
2016 Q1 / 10,033 / 1,205 / 4,912 / 3,511 / 405
2016 Q2 / 10,445 / 1,253 / 5,290 / 3,465 / 436
2016 Q3 / 11,337 / 1,218 / 5,947 / 3,779 / 392
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / -21.433 / -7.202 / -16.596 / -10.577 / -4.357
p-value / 0.000 / 0.000 / 0.000 / 0.000 / 0.000
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / -2.500 / -2.003 / -0.895 / -1.429 / -2.191
p-value / 0.012 / 0.045 / 0.371 / 0.153 / 0.028
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.4Inpatient stays with a diagnosis of opioid dependence by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 25,812 / 2,730 / 12,263 / 8,739 / 2,078
2015 Q2 / 26,968 / 2,703 / 13,129 / 9,100 / 2,035
2015 Q3 / 28,098 / 2,879 / 13,792 / 9,340 / 2,083
2015 Q4 / 29,681 / 2,722 / 13,636 / 10,492 / 2,829
2016 Q1 / 29,746 / 2,728 / 13,401 / 10,709 / 2,906
2016 Q2 / 30,748 / 2,498 / 14,140 / 11,038 / 3,072
2016 Q3 / 31,669 / 2,463 / 14,819 / 11,179 / 3,208
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / -2.683 / -2.893 / -7.732 / 2.552 / 7.600
p-value / 0.007 / 0.004 / 0.000 / 0.011 / 0.000
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / -2.018 / -3.985 / -1.050 / -1.216 / 2.474
p-value / 0.044 / 0.000 / 0.294 / 0.224 / 0.013
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.5Inpatient stays with a diagnosis of adverse effects of opioids by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 8,436 / 478 / 1,062 / 2,784 / 4,112
2015 Q2 / 8,588 / 410 / 1,131 / 2,914 / 4,133
2015 Q3 / 9,086 / 460 / 1,248 / 3,013 / 4,364
2015 Q4 / 14,826 / 734 / 1,902 / 5,107 / 7,082
2016 Q1 / 15,065 / 706 / 2,029 / 5,165 / 7,165
2016 Q2 / 15,330 / 750 / 2,093 / 5,325 / 7,161
2016 Q3 / 15,706 / 801 / 2,163 / 5,339 / 7,398
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / 22.767 / 6.040 / 5.216 / 14.106 / 15.989
p-value / 0.000 / 0.000 / 0.000 / 0.000 / 0.000
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / -1.787 / 2.033 / -1.955 / -1.441 / -1.032
p-value / 0.074 / 0.042 / 0.051 / 0.150 / 0.302
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.6Inpatient stays with a diagnosis of opioid poisoning by patient age, 2015 quarter 1 through 2016 quarter 3
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q1 / 5,588 / 682 / 1,906 / 2,222 / 776
2015 Q2 / 5,835 / 706 / 2,055 / 2,310 / 762
2015 Q3 / 6,126 / 711 / 2,114 / 2,521 / 779
2015 Q4 / 5,367 / 514 / 1,691 / 2,209 / 950
2016 Q1 / 5,317 / 498 / 1,636 / 2,188 / 995
2016 Q2 / 5,586 / 515 / 1,811 / 2,249 / 1,011
2016 Q3 / 5,911 / 508 / 1,986 / 2,400 / 1,017
Compare trend before the ICD transition (Q1–Q3 2015) to during the ICD transition (Q3–Q4 2015)
Chi-square statistic / -8.443 / -4.244 / -6.909 / -6.223 / 2.899
p-value / 0.000 / 0.000 / 0.000 / 0.000 / 0.004
Compare trend before the ICD transition (Q1–Q3 2015) to after the ICD transition (Q1–Q3 2016)
Chi-square statistic / 0.557 / -0.267 / 2.092 / -0.857 / 0.269
p-value / 0.578 / 0.789 / 0.036 / 0.391 / 0.788
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
Table B.7Inpatient stays with a diagnosis of opioid use, unspecified,by patient age, 2015 quarter 4 through 2016 quarter 3a
Year and Quarter / All Ages / Ages 0–24 / Ages 25–44 / Ages 45–64 / Ages 65 and older2015 Q4 / 4,041 / 512 / 1,695 / 1,304 / 529
2016 Q1 / 4,363 / 551 / 1,930 / 1,359 / 523
2016 Q2 / 4,466 / 518 / 2,135 / 1,377 / 436
2016 Q3 / 4,517 / 507 / 2,108 / 1,412 / 489
a Codes that identify opioid use, unspecified, are only available under ICD-10-CM (starting in quarter 4 of 2015). No significance tests were conducted for this diagnosis type.
Source: Agency for Healthcare Research and Quality, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, State Inpatient Databases, 2015–2016, 14 States.
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