Binding, antioxidant and proliferative properties of bioactive compounds of sweet Paprika (Capsicum annuum L.)

Plant Foods for Human Nutrition

Hong-Gi Kim1, Jong-Hyang Bae2,3, Zenon Jastrzebski4, Andriy Cherkas5, Buk-Gu Heo6, Shela Gorinstein7*, Yang-Gyu Ku2,3, *

*Corresponding authors:

Shela Gorinstein, Institute for Drug Research, School of Pharmacy, the Hebrew University, Hadassah medical School, Jerusalem 91120, Israel; Tel/Fax:+972 (2)6758690/+972 (2)6757076;Email:

Yang-Gyu Ku, Department of Horticulture Industry, College of Life Science and Resource, Wonkwang University, Iksan 54538, Korea; 3Institute of Life Science and Natural Resources, Wonkwang University, Iksan 54538, Korea; Tel/Fax: +82 (63)506672/+82(63)8507308; E-mail:

Table 2 (A) Survival rate of lung cancer (Calu6) cells of paprika fruit extracts of two extract method and two types of lamps (high pressure sodium (HPS) and lighting emitting plasma (LEP) lamps; (B) Survival rate of lung cancer (Calu6) cells of paprika fruits of two extract methods.

A

Extract Treatment / Survival rate of lung cancer (Calu6) cellz
50 mg L-1 / 100 mg L-1 / 200 mg L-1 / 400 mg L-1 / 800 mg L-1
Distilled water / Control / 52.0±0.5cy / 51.1±4.6c / 41.1±1.3b / 39.4±1.5a / 29.0±0.6c
HPS / 78.3±5.1a / 73.7±0.7a / 64.8±0.9a / 65.4±3.4b / 54.7±0.8b
LEP / 64.8±3.9b / 64.8±1.9b / 64.5±4.0a / 68.5±3.0a / 67.3±3.7a
Ethanol / Control / 64.4±0.9b / 69.2±2.6ab / 68.7±1.0a / 67.2±2.6a / 68.5±1.6a
HPS / 65.2±1.2b / 66.1±1.7ab / 66.9±1.0a / 64.6±1.2a / 64.0±2.3a
LEP / 77.4±2.0a / 65.5±1.9ab / 68.2±6.1a / 66.8±4.3a / 67.1±0.6a
Extractx / NS / NS / *** / ** / ***
Treatment / *** / ** / ** / *** / ***
Extract x Treatment / *** / *** / ** / *** / ***

zEach value is the mean of three replications per treatment.

yMeans within columns sharing the same letter are not significantly different by Duncan’s multiple range test at P≤ 0.05. xNS, *, **, *** indicates not significant or significant at the P≤ 0.05, or P≤ 0.01, or P≤ 0.001 level, respectively.

B

Extract / Survival rate of lung cancer (Calu6) cellz
50 mg L-1 / 100 mg L-1 / 200 mg L-1 / 400 mg L-1 / 800 mg L-1
Distilled water / 65.04ay / 63.24a / 56.85b / 57.80b / 50.38b
Ethanol / 69.05a / 66.95a / 67.97a / 66.23a / 66.58a

zEach value is the mean of nine replications per treatment. yMeans within columns sharing the same letter are not significantly different by Duncan’s multiple range test at P≤ 0.05.