SUMMER NEUROPEPTIDE CONFERENCE (SNP)

STADY V MEETING (International Symposium on Signal Transduction in Health and Disease)

October 22-24 Tel-Aviv, Israel

Orgenizers:

Illana Gozes & Zvi Naor (Israel)

Committees:

SNC / STADY V
Meeting Chairs / Meeting Chairs
Illana Gozes ( Israel ) / Zvi Naor (Israel)
Y Peng Loh (USA) / Illana Gozes ( Israel )
Douglas E. Brenneman ( USA )
Organizing Committee / Organizing Committee
T.W. Moody / N. Zisapel
D. Gehlert (Secretariat) / AD Korcyzn
I. Antal (Treasurer, Finances) / Y. Gothilf
A. Kopin (Treasurer, Finances) / R. Seger
K. Seroogy (Finances) / Y. Koch
L. Hersh (Finances)
J. Crawley
J. Pisegna
F. Strand
Wednesday, October 22, 2008
Lectures will be held at the Tel Aviv University, Dolfi and Lola Ebner Auditoriums, Sackler Faculty of Medicine. Entrance is from gate 1 on October 22 and 23, and from gate 8 on Friday October 24.
Wednesday, October 22, 2008
08:45-09:00 / Greetings : Levitan Dan – Rector of TAU
Kloog Yoel – Dean of the Faculty of Life Sciences
Mekori Yoseph - Dean of the Faculty of Medicine
09:00-09:50
Dolfi Enber Auditorium / FOCUS ON ALZHEIMER’S AND GNRH SIGNALING:
FROM THE MEETING ORGENIZERS
09:00-09:25 / AL-108: A case study for drug discovery and development toward cognitive enhancement and neuroprotection
Gozes Illana
09:25-09:50 / GnRH receptor signaling
Naor Zvi
09:50-10:10 / Coffee Break
10:10-12:15
Dolfi Enber Auditorium / SYMPOSIUM I
ALZHEIMER’S DISEASE
In memory of the late Prof. Irith Ginzburg
Chairs: Littauer Uriel, James Miller & Illana Gozes
10:10-10:35 / Novel inhibitors of BACE-1: comparitive pharmamacology of 2-aminoheterocycles
Brenneman Douglas
10:35-11:00 / A novel method to treat Alzheimer's disease: peripheral expression on the peptidase neprilysin
Hersh Louis B
11:00-11:25 / Cystatin C binds amyloid b and inhibits its oligomerization, fibril formation, and deposition in Alzheimer's disease mouse models
Levy Efrat
11:25-11:50 / Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ROS
Shoval Hilal
11:50-12:15 / Cross talk interactions between apolipoprotein E4 and oligomerized Amyloid–β
Michaelson Daniel
12:15-14:00 / Lunch and Posters
10:10-12:15
Lola Enber Auditorium / SYMPOSIUM II
GnRH: FROM NEURON TO RECEPTOR
Chair Zvi Naor
10:10-10:35 / Regulatory functions of estrogen receptor-alpha and -beta subtypes expressed in hypothalamic GnRH neurons
Catt Kevin
10:35-11:00 / Multiple targets of calcineurin in GnRH signalling to gonadotropin gene expression
Melamed Philippa
11:00-11:25 / Journey to the hypothalamus, travels of the GnRH neuron
Mellon Pamela
11:25-11:50 / Hormonal regulation of LH and GnRH mRNA expression in cultured rat granulose cells
Koch Yitzhak
11:50-12:15 / Signalling events in derepression of the LH receptor transcription
Dufau Maria
12:15-14:00 / Lunch + Posters
14:00-15:15
Dolfi Auditorium / SYMPOSIUM III
PROCESSING AND DEVELOPMENT
14:00-14:25 / Systemic consequences to local lose of notch signaling
Kopan Raphael
14:25-14:50 / Carboxypeptidase E in Neuroprotection and Cancer
Loh Peng
14:50-15:15 / Organizer-specific p38 MAPK-CREB pathway functions to pattern mesoderm in the frog Xenopus laevis
Bengal Eyal
15:15-15:40 / Coffee Break
15:40-16:55
Dolfi Auditorium / SYMPOSIUM IV
FOCUSING ON THE CNS
15:40-16:05 / Mechanisms of cell death in oligodendrocytes after proteasomal inhibition.
Richter-Landsberg Christiane
16:05-16:30 / Chromatin remodeling in cortical development
Agoston Denes V.
.
16:30-16:55 / Localisation and function of the novel neuropeptide alarin in the central nervous system
Kofler Barbara
16:55-19:00 / Dinner + Posters
14:00–15:15
Lola Ebner Auditorium / SYMPOSIUM V
BIOLOGICAL CLOCK
14:00-14:25 / Developmental and Circadian Control of the Pineal Transcriptome
Klein David
14:25-14:50 / Melatonin signaling in the human brain and its relevance to the treatment of insomniaand circadian rhythm sleep disorders
Zisapel Nava
14:50-15:15 / Zebrafish shed light on light-entrainment of the circadian clock
Gothilf Yoav
15:15-15:40 / Coffee Break
15:40–16:55
Lola Ebner Auditorium / SYMPOSIUM VI
OOCYTES
15:40-16:05 / Steroids and resumption of oocyte meiosis: Are mammals so much distinct?
Tsafriri Alex
16:05-16:30 / An LH-induced elevation in intraoocyte cAMP triggers PDE3A activation facilitating meiosis reinitiation
Dekel Nava
16:30-16:55 / Resumption of the second meiotic division in oocytes- - SFKS (SRC family kinases) signalling
Shalgi Ruth
16:55-19:00 / Dinner + Posters
Thursday, October 23, 2008
09:00–12:25
Dolfi Enber Auditorium / SYMPOSIUM VII
DEPRESSION (Chair: Ildiko Antal)
09:00-09:25 / The Role of Melanin Concentrating Hormone Receptor, MCHR1, in mood disorders
Antal Ildiko
09:25-09:50 / Behavioral Phenotypes of GALR1/GALR2 Double Knockout Mice: Relevance for Anxiety– and Depression-Related Behaviors
Bailey Kathleen
09:50-10:15 / The role of Ghrelin in feeding and memory performance
Daino Sabrina
10:15-10:40 / PTSD/rat models
Yadid Gal
10:40-11:10
Coffee Break
11:10-11:35 / PACAP
Pinhasov Albert
11:35-12:00 / Mesenchymal Stem Cells as a novel treatment for depressive disorders
Turgeman Gadi
12:00-12:25 / Galaninergic signaling in depression
Or IL-1 signaling in fever and inflammatory disease
Bartfai Tamas
12:30–13:30 / Lunch and Posters
09:00–12:25
Lola Enber Auditorium / SYMPOSIUM VIII
UPDATE ON SIGNAL TRUNSDUCTION I
09:00-09:25 / Studying inositol lipid-based signaling with novel molecular tools
Balla Tamas
09:25-09:50 / Dynamics of Ras and Src membrane interactions and their relation to signaling
Henis Yoav
09:50-10:15 / The mechanism and function of MEK and ERK translocation into the nucleus
Seger Rony
10:15-10:40 / Kisspeptin signaling in the brain: Implications for puberty onset and female reproductive health
Tena-Sempere Manuel
10:40-11:10 / Coffee Break
11:10-11:35 / PKCα Degradation During Sperm Capacitation Leads to PKA-Mediated PI3K Activation
Breitbart Haim
11:35-12:00 / IGF-1 inhibits ER stress-induced apoptosis; mechanisms and implications
Leroith Derek
12:00-12:25 / Signaling by Purinergic P2X Receptor Channels
Stojilkovic Stanko
12:30-13:30 / Lunch and Posters
13:30–17:10
Dolfi Enber Auditorium / SYMPOSIUM IX
NEUROPATHY, DIABETES AND METABOLISM
13:30-13:55 / Neuropeptide and Cytokines interact in upwinding chronic pain
Zimmermann Manfred
13:55-14:20 / Physiopathological involvement of ghrelin in the control of growth and energy metabolism
Epelbaum Jacques
14:20-14:45 / Microglia activation in health and disease
Rotshenker Shlomo
14:45-15:10 / The role of CD59 in neuropathy
Chorev Michael
15:10-15:35 / From trophic factors to small molecule therapeutics for neurodegenerative diseases (and other indications)
Pruss Rebecca
15:35-15:55 / Coffee Break
15:55-16:20 / PACAP Regulation of Gastrointestinal Secretion and Motility
Pisegna Joseph R.
16:20-16:45 / Urocortins: emerging metabolic and energy homeostasis perspectives
Chen Alon
16:45-17:10 / Hypothalamic neuropeptides controlling energy balance
Nillni Eduardo A
17:10 / Posters + Dinner
13:30–15:35
Lola Enber Auditorium / SYMPOSIUM X
SIGNAL TRUNSDUCTION IN PARKINSON DISEASE :
13:30-13:55 / TBD
Youdim Moussa B.H.
13:55-14:20 / Signal Transduction pathway involved in the mechanism of action of the anti-Parkinson's drug rasagiline and its derivatives
Weinreb Orly
14:20-14:45 / Susceptibility Genes, Their Proteins And Treatment Targets In Sporadic Parkinson's Disease
Mandel Silvia
14:45-15:10 / Chemokines are neuromodulators of dopaminergic transmission
Rostene William
15:10-15:35 / TBD
Offen Daniel
15:35-15:55 / Coffee Break
15:55–17:10
Lola Enber Auditorium / SYMPOSIUM XI
UPDATE ON SIGNAL TRUNSDUCTION II
15:55-16:20 / GSK-3:the link between metabolism and neurodegenerative disorders
Eldar Hagit
16:20-16:45 / Novel Wnt/beta-catenin target genes in epithelial plasticity and invasive tumor development
Ben-Ze'ev Avri
16:45-17:10 / Extermination of human breast cancer MCF-7 cells
by phenanthridine derived PARP inhibitors
Cohen-Armon Malka
17:10 / Posters + Dinner
Friday, October 24, 2008
09:00–11:30
Lola Ebner Auditorium / SYMPOSIUM XII
THE MANY FACES OF NEUROPEPTIDES
09:00-09:25 / Novel neuropeptide and cytokine responsive genes in the nervous system: discovery through microarray analyses in cells and in vivo
Eiden Lee
09:25-09:50 / Signaling events regulating corticotrophin releasing hormone expression
Aguilera Greti
09:50-10:15 / Emerging role for neuropeptides in host-virus interaction
Weihe Eberhard
10:15-10:40 / Insect neuropeptides: Challenges and achievements.
Altstein Vinnie
10:40-11:05 / Coffee Break
11:05-11:30 / Low Molecular Weight Ligands for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism and Thyroid Cancer
Gershengorn Marvin
11:30-12:00 / Special interest lecture:
Retroviral vectors and translational approaches to diseases of the nervous system
Eiden Maribeth V.
12:00-12:30 / YOUNG INVESTIGATORS AWARD CEREMONY
12:30-12:45 / CONCLUSIONS