Curriculum Vita

Mu-ming Poo

BIRTHDATE: October 31, 1948 Born: Nanjing, China CITIZENSHIP: U.S. (naturalized)

EDUCATION: B.S. (physics), Tsinghua University, Taiwan (1970)

Ph.D. (biophysics), Johns Hopkins University (1974)

POSITIONS:

1974 - 1976: Postdoctoral Fellow, Marine Biological Laboratory, Woods Hole, and Department of Biological Sciences, Purdue University.

1976 - 1979: Assistant Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1979 - 1983: Associate Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1983 - 1985: Professor, Dept. of Physiology and Biophysics, Univ. Calif. at Irvine.

1985 - 1988: Research Professor, Section of Molecular Neurobiology, Yale Univ. School of Medicine

1988 - 1995: Professor, Dept. of Biological Sciences, Columbia University.

1996 - 2000: Stephen W. Kuffler Professor in Neurobiology, Dept. of Biology, Univ. Calif. San Diego.

1999 - : Director, Institute of Neuroscience, Chinese Academy of Sciences, Shanghai

2000 - 2005: Professor of Neurobiology, Class of 1933 Chair in Biological Sciences, U.C. Berkeley

2002 - : Head, Division of Neurobiology, Dept. of Molecular and Cell Biology, U.C. Berkeley

2005 - : Paul Licht Distinguished Professor in Biology, U. C. Berkeley

PROFESSIONAL ACTIVITIES, HONORS, and Services:

1985 - 1988: Developmental Neuroscience Panel, National Science Foundation.

1989 - 1993: Cell Biology and Physiology Study Section, National Institutes of Health.

1989 - 1991: Preparatory Advisory Committee, Hong Kong University of Science and Technology

1997 - 1999: Long-term Fellowship Review Board, Human Frontier Science Program.

1998 - 2005: Javitz Neuroscience Investigator Award.

2000 : Academician, Academia Sinica, Taiwan (2000)

2001 : Fellow, American Association for Advancement of Science

2001 : Ameritec Prize (2001)

2002 - : Executive Committee, Helen Wills Neuroscience Institute, U.C. Berkeley

2002 - : IBRO Program Committee and Neuroscience School Board

2002 - : Chair, Advisory Board, Brain Research Center, University System of Taiwan (2002-)

2002 : Ray Wu Society Award

2003 : Docteur Honoris Causa, Ecole Normale Supérieure, Paris

2003 - : Advisory Board, RIKEN Brain Science Institute, Tokyo, Japan

2004 - 2005: Peter Gruber Foundation Neuroscience Prize Committee

2005  : Academic Review Committee (Ad hoc), Friedrich Miescher Institute, Switzerland

Editorial Boards: Neuron (99-), Journal of Neuroscience (99-04), Journal of Cell Biology (94-01), Journal of Biomedical Sciences (94-99), NeuroSignals (01-). Biochemical and Biophysical Research Communications (03-). Current Opinion in Neurobiology (04-). Network (05-). Progress in Neurobiology (05-)

Special Lectures, Symposia, and Conferences (since 1998)

1998 

Bauer Colloquium, Volen Center of Complex Systems, Brandeis University.

Munich Neuroscience Colloquium, Max-Planck Institute for Neurobiology, Martinsreid.

Banburg Conference on “Computational Neuroscience: from Synapse to Behavior”

Keystone Symposia “Synapse Formation and Function: from Neuromuscular Junctions to CNS”

Gordon Conference on “The Cell Biology of Neuron”, New Hampshire.

FASEB Summer Research Conference on “Calcium and Cell Function”, Snowmass, Colorado.

Gordon Conference on “Molecular and Cellular Neurobiology”, Beijing, China.

Conference on “Directional Cell Movement and Axonal Growth Cones”, Ringberg, Germany.

Center of Excellence Symposium on “Plasticity and Regeneration of Neural Network”, Tokyo.

Symposium on “Neural Plasticity”, Japanese Society for Neuroscience Annual Meeting, Tokyo

1999

International Symposium on Neuroplasticity, Taipei.

HFSP Forum on “Wiring Molecules in Brain Development and Plasticity”, Tokyo (1999).

Fourth Symposium of Life Sciences, Shanghai Life Sciences Research Center, Shanghai.

Gordon Conference on “Neurotrophins”, Newport, Rhode Island.

IBRO symposia “neurotrophin and synaptic plasticity” and on “synaptogenesis”, Jerusalem.

Fourth International Symposium of SCBA, Hong Kong.

EMBO-FMI Conference “Neuronal Circuits: From Molecules to Organisms”, Ascona, Switzerland

EMBO Workshop on “Axonal Guidance and Neural Plasticity”, Varrenna, Italy.

Brain Science Institute Symposium on “Molecular Dynamics of Cell Function”, RIKEN, Tokyo.

2000

Givaudan-Roure Lecture, Association for Chemoreception Sciences, Sarasota

Gordon Research Conference on Neural Plasticity, Newport, Rhode Island

Symposium on growth cone guidance, Japanese Society of Neurochemistry, Yokohama, October (2000).

Xian symposium on neuroregeneration, Xian, China

Special Lecture, Society for Neuroscience Annual Meeting, New Orleans.

2001

Sackler Colloqium on Neural Signaling, NAS, Washington, D.C. February (2001).

Keystone symposium on “The synapse”, Taos, New Mexico, March (2001).

Neural Information and Coding Workshop, Big Sky, Montana, March (2001).

Plenary lecture, Society for Neuroscience of Africa, Nairobi, Kenya, April (2001).

Second International symposium on Learning and Memory, Taipei, Taiwan, May (2001)

Salk symposium on axon guidance and growth cone dynamics, Salk Institute, La Jolla, May (2001).

Second Fudan Symposium on Developmental Biology and Genetics, Shanghai, June (2001).

Sloan-Swartz Center Annual Retreat, July, Tahoe (2001)

Second MIT-RIKEN Symposium on Frontier in Neuroscience, Cambridge (2001)

Richard Bunge Memorial Lecture, University of Miami, October 12 (2001).

2002

Workshop on “How cell interpret gradients”, Napa, California

Oversea Lecturer, Australian Society of Neuroscience Meeting, Sydney, Australia.

Keystone Symposium on “Cellular Motility and Signaling in the Wiring and Plasticity of Nervous Systems”, Taos, New Mexico

Gordon Research Conference on Molecular and Cellular Neurobiology, Hong Kong

Human Frontier Science Program Lecture, 3rd Forum of European Neuroscience

Gordon Research Conference on Synapse, New Hampshire

Symposium on Cognitive Neuroscience of Learning and Memory, Beijing

Keystone Symposium on Axonal Connections: Molecular Cues for Development and Regeneration, Keystone, Colorado

Distinguished Neuroscience Lecture Series, University of Toronto

2003

Symposium “Frontier of Neuroscience”, Brain Research Center of UST, Taipei, Taiwan

RIKEN Center for Developmental Biology Symposium: The Origin and Formation of Multicellular Systems, Kobe, Japan

Cold Spring Harbor Laboratory Conference on Learning and Memory

Blankenese Symposium on “Learning at the Synapse” Hamburg, Germany

Gordon Research Conference on "Neural Plasticity" Newport, Rhode Island

Symposium on Synaptogenesis, Vienna, Austria

IBRO Congress symposium on “Calcium signaling in development and plasticity” Prague, Czech

TINS Lecture, INMED Conference “Nature and Nurture in Brain Development” La Ciotat, France

Samsung International Symposium on Molecular Medicine “Neurological Diseases”, Seoul, Korea

University Lecture Series, Rockefellor University

Public Lecture, Docteur Honoris Causa, Ecole Normale Supérieure, Paris

2004

COE Symposium on plasticity of neural circuits, Institute of Neuroscience, Tokyo

Gordon Conference on Molecular and Cellular Neurobiology, Hong Kong

Keynote Lecture, Gordon Conference on Bioelectrochemistry, New London

Plenary Lecture, Japanese Society for Neuroscience Annual Meeting, Osaka

Plenary Lecture, International Meeting of Physiological Society of China, Beijing

Teuber Lecture, MIT

2005

Merck/UCSD Symposium on Synaptic Plasticity

Keystone Symposium Axonal Connections: Molecular Cues for Development and Regeneration”

Plenary Lecture, European Society of Cognitive Science, Dublin

Gordon Conference on “Gradient Sensing & Directed Cell Migration”, Ventura, California

Institute for Advanced Studies, School of Dendrite, Hebrew University

Gordon Conference on “Inhibition in the CNS”, New London, Connecticut

Gordon Conference on “Cellular Signaling Mechanisms”, Hong Kong

Basic Neurochemistry Plenary Lecture, American Society for Neurochemistry, Madison, Wiscosin

EMBO-FMI Conference “Formation and Plasticity of Neuronal Circuits”, Ascona, Switzerland

Heller Lecture in Computational Neurobiology, Hebrew University (2005)

Grass Foundation Lecturer, University of Wiscosin, Madison (2005)

Plenary Lecture, Lemanic Neuroscience Program Retreat, Switzerland

Invited Seminars (since 1998):

1998

Frontier in Neuroscience Seminar Series, Stanford University School of Medicine.

NIH Neuroscience Seminar Series

Department of Cell and Molecular Biology, Harvard University

Department of Neuroscience, Scripps Research Foundation.

Neuroscience Program, Johns Hopkins University School of Medicine.

Department of Neurobiology, University of Pittsburgh School of Medicine.

Neuroscience Program, UCLA.

Department of Biology, University of Illinois.

Hemholtz Club, University of California, Irvine.

Salk Institute Seminar Series.

Department of Neurobiology, Duke University.

Department of Cell Biology, Harvard Medical School.

Cold Spring Harbor Course on Developmental Neurobiology.

Department of Brain and Cognitive Science, MIT

1999

Salt Institute Seminar Series

Department of Neurobiology, Duke University

Department of Cell Biology, Harvard Medical School

Neuroscience Colloquium Series, State University of New York in Buffalo

Department of Neuroscience, Case Western Reserve University

Department of Pharmacology, University of Virginia School of Medicine

Department of Pharmacology, The Mount Sinai Medical Center

2000

Program in Neurobiology and Developmental Biology, UCSF

California College of Medicine, University of California at Irvine

Department of Pharmacology, University of Maryland School of Medicine

Department of Neuroscience, Baylor College of Medicine.

Neuroscience Program, University of Michigan.

Nara Institute of Science and Technology, Nara, Japan

2001

Neuroscience Research Group, University of Calgary.

BIO-X Seminar Series, Stanford University

2002

Department of Neuroscience, Children’s Hospital, Harvard Medical School

2003

Division of Biology, Caltech.

2004

Neuroscience Colloquium, Rutger-Newark Center for Molecular and Behavioral Neuroscience

Neuroscience Program Seminar, Johns Hopkins University School of Medicine

Neuroscience Program Seminar, University of Washington

Neuroscience Research Center Lecture series, Stanford University

Vollum Institute Seminar, Portland

Neuroscience Program Seminar, University of Chicago

2005

Department of Neurobiology, Weizmann Institute

Departmental Seminar, Molecular and Cellular Biology, Harvard University

PUBLICATIONS:

1. Poo, M-m. and R.A. Cone. Lateral diffusion of rhodopsin in Necturus rod. Exp. Eye Res. 17:503-514 (1973).

2. Poo, M-m. and R.A. Cone. Lateral diffusion of rhodopsin in the photoreceptor membrane. Nature 247:438-441 (1974).

3. Nuccitelli, R., Poo, M-m. and L.F. Jaffe. Relations between ameboid movement and membrane-controlled electrical currents. J. Gen. Physiol. 69:743-763 (1977).

4.  Hudspeth, A.J., Poo, M-m. and A.J. Stuart. Passive signal propagation and membrane properties in medial photoreceptors of the giant barnacle. J. Physiol. (Lond.) 272:25-43 (1977).

5.  Poo, M-m. and K.R. Robinson. Electrophoresis of concanavalin A receptors in the membrane of embryonic muscle cells. Nature 265:602-605 (1977).

6. Poo, M-m., Poo, W-j.H. and J.W. Lam. Lateral electrophoresis and diffusion of Concanavalin A receptors in the membrane of embryonic muscle cells. J. Cell Biol. 76:483-501 (1978).

7. Orida, N.K. and M-m. Poo. Electrophoretic movement and localization of acetylcholine receptors in the embryonic muscle cell membrane. Nature 275: 31-35 (1978).

8. Poo, M-m., Lam, J.W., Orida, N.K. and A.W. Chao. Electrophoresis and diffusion in the plane of cell membrane. Biophys. J. 26:1-22 (1979).

9. Jaffe, L.F. and M-m. Poo. Neurites grow faster towards the cathode than the anode in a steady field. J. Exp. Zool. 209:115-127 (1979).

10. Poo, M-m. Molecular movement of cell surface receptors. Biorheology 16: 309-315 (1979).

11. Orida, N.K. and M-m. Poo. On the developmental regulation of acetylcholine receptor mobility in the Xenopus embryonic muscle membrane. Exp. Cell Res. 130:281-290 (1980).

12. McLaughlin, S. and M-m. Poo. The role of electro-osmosis in the electric field-induced movement of charged macromolecules on the cell surface. Biophys. J. 34:85-93 (1981).

13. Orida, N. and M-m. Poo. Maintenance and dissolution of acetylcholine receptor clusters in the embryonic muscle cell membrane. Dev. Brain Res. 1:293-298 (1981).

14. Chao, N-m., Young, S.H. and M-m. Poo. Localization of cell membrane components by surface diffusion into a "trap". Biophys. J. 36:139-153 (1981).

15.  Poo, M-m. In situ electrophoresis of membrane components. Ann. Rev. Biophys. Bioeng. 10:245-276 (1981).

16. Patel, N. and M-m. Poo. Orientation of neurite growth by extracellular electric field. J. Neurosci. 2:483-496 (1982).

17. Poo, M-m. Rapid lateral diffusion of functional acetylcholine receptors in embryonic muscle membrane. Nature 295:332-334 (1982).

18. Chow, I. and M-m. Poo. Redistribution of cell surface receptors induced by cell-cell contact. J. Cell Biol. 95:510-518 (1982).

19. Fraser, S.E. and M-m. Poo. Development, maintenance, and modulation of patterned membrane topography. Models based on acetylcholine receptors. Curr. Top. Dev. Biol. 17:77-100 (1982).

20. Young, S.H. and M-m. Poo. Rapid lateral diffusion of extrajunctional acetylcholine receptors in Xenopus tadpole myotomes. J. Neurosci. 3:225-231 (1983).

21. Young, S.H. and M-m. Poo. Topographic rearrangment of ACh receptors alters channel kinetics. Nature 304:161-163 (1983).

22. Wu, C-f., Suzuki, N. and M-m. Poo. Dissociated neurons from normal and mutant Drosophila larval CNS in cell culture. J. Neurosci. 3:1888-1899 (1983).

23. Young, S.H. and M-m. Poo. Spontaneous release of transmitter from growth cone of embryonic neuron. Nature 305:634-637 (1983).

24. Chow, I. and M-m. Poo. Formation of electrical coupling between embryonic Xenopus muscle cells in culture. J. Physiol. (Lond.) 346:181-194 (1984).

25. McCloskey, M. and M-m. Poo. Protein diffusion in cell membranes: Some biological implications. Int. Rev. Cytol. 87:19-81 (1984).

26. Lin-Liu, S., Adey, W.R. and M-m. Poo. Migration of cell surface concanavalin A receptors in pulsed electric fields. Biophys. J. 45:1121-1218 (1984).

27. McCloskey, M., Liu. Z. and M-m. Poo. Lateral electromigration and diffusion of Fc receptors on rat basophilic leukemia cells: Effects of IgE binding. J. Cell Biol. 99:778-787 (1984).

28. Young, S., McCloskey, M. and M-m. Poo. Migration of cell surface receptors induced by extracellular electric fields: Theory and applications. The Receptors Vol. 1, M.Conn ed., pp. 511-539. Academic Press, Inc. (1984).

29. Patel, N.B. and M-m. Poo. Perturbation of the direction of neurite growth by pulsed and focal electric fields. J. Neurosci. 4:2939-2947 (1984).

30.  Patel, N.B., Xie Z-p., Young, S. and M-m. Poo. Response of nerve growth cone to focal electric currents. J. Neurosci. Res. 13:245-256 (1985).

31. Poo, M-m. Mobility and localization of proteins in excitable membranes. Ann. Rev. Neurosci. 8:368-406 (1985).

32. Sun, Y-a. and M-m. Poo. Non-quantal release of acetylcholine at a developing neuromuscular synapse in culture. J. Neurosci. 5:634-642 (1985).

33. Chow, I. and M-m. Poo. Release of acetylcholine from embryonic neurons upon contact with muscle cell. J. Neurosci. 5:1076-1082 (1985).

34. Poo, M-m., Sun, I-a. and Young, S. Three types of transmitter release from embryonic neurons in culture. J. Physiol. (Paris) 80: 283-298 (1985).

35. McCloskey, M. and M-m. Poo. Rates of membrane-associated reactions: Reduction of dimensionality revisited. J. Cell Biol. 102:88-96 (1985).

36. Peng, H.B. and M-m. Poo. Formation and dispersal of acetylcholine receptor clusters in muscle membranes. Trends in Neurosci. 9:125-129 (1986).

37. McCloskey, M. and M-m. Poo. Contact-induced redistribution of specific membrane components: Local accumulation and development of adhesion. J. Cell Biol. 102:2185-2196 (1986).

38. Xie, Z-p. and M-m. Poo. Initial events in the formation of neuromuscular synapse: Rapid induction of acetylcholine release. Proc. Natl. Acad. Sci. USA 83:7069-7073 (1986).

39. Sun, Y-a. and M-m. Poo. Evoked release of transmitter from growing embryonic neuron. Proc. Natl. Acad. Sci. USA 84:2540-2544 (1987).

40. Torney, D., Warnock T. McCloskey, M. Dembo M., and M-m. Poo. Rate theories for chemical reactions taking place in two dimensions. Comments Mol. Cell. Biophys. 4:281-303 (1987).

41. Poo, M-m. Transmitter release and synaptogenesis. In Peripheral Nerve Regeneration, ed. T Gordon and G. Vrbova, Alan R. Liss, Inc. p.203-212 (1987).