Online Resource1: Talairach coordinates of significant cerebral cortical hypoperfusions (p < 0.001 for the voxel, uncorrected) in AD patients in comparison to the healthy subjects. Results from SPM8 are listed in decreasing order of peak T-score value, k values represent the number of significant voxels in the particular cluster.

Cluster
p (cor) / cluster
k / voxel
T-score / Coordinates {mm} / Brain region
x / y / z
<0.001 / 30247 / 5.45 / -14 / 48 / 38 / Left parietal lobe, precuneus (BA 31)
5.43 / -44 / 42 / 26 / Left insula (BA 13)
5.42 / 14 / -48 / 38 / Right parietal lobe, precuneus (BA 31)
5.41 / -44 / -44 / 30 / Left parietal lobe, supramarginal gyrus(BA 40)
5.30 / -8 / 4 / 10 / Left caudate nucleus body
5.08 / -12 / -32 / 42 / Left limbic lobe, cingulate gyrus (BA 31)
5.00 / -30 / -50 / 40 / Left parietal lobe, superior lobule (BA 7)
4.98 / -26 / -50 / 42 / Left parietal lobe, precuneus (BA 7)
4.85 / 10 / 2 / 16 / Right caudate nucleus body
4.76 / -6 / -46 / 26 / Left limbic lobe, posterior cingulum (BA 23)
4.76 / -4 / -2 / 38 / Left limbic lobe, cingulate gyrus (BA 24)
4.70 / -50 / -18 / -20 / Left temporal lobe, middle gyrus (BA 21)
4.67 / -36 / -38 / -10 / Left temporal lobe, fusiform gyrus (BA 37)
4.59 / 30 / -52 / 40 / Right parietal lobe,superior lobule (BA 7)
4.57 / -22 / -36 / 6 / Left thalamus
4.56 / -30 / -38 / -2 / Left temporal lobe, hippocampus
4.55 / 28 / -50 / 44 / Right parietal lobe, precuneus (BA 7)
4.55 / 4 / -44 / 28 / Right limbic lobe, cingulate gyrus (BA 31)
4.54 / -8 / -12 / 40 / Left limbic lobe, cingulate gyrus (BA 24)
4.50 / -36 / -30 / -22 / Left limbic lobe, parahippocampal gyrus (BA 36)
4.50 / -24 / -38 / 2 / Left limbic lobe, parahippocampal gyrus (BA 30)
4.47 / -38 / -56 / 30 / Left temporal lobe, superior gyrus (BA 39)
4.47 / -46 / -52 / -2 / Left temporal lobe, middle gyrus (BA 37)
4.44 / -18 / -34 / 10 / Left thalamus (pulvinar)
4.42 / 48 / -40 / 50 / Right parietal lobe, inferior lobule (BA 40)
0.015 / 1269 / 4.10 / 32 / -12 / -28 / Right limbic lobe, hippocampus
4.04 / 34 / -12 / -24 / Right limbic lobe, parahippocampal gyrus (BA 28)
4.03 / 30 / -14 / -24 / Right occipital lobe, fusiform gyrus (BA 37)
3.91 / 20 / -8 / -22 / Right limbic lobe, parahippocampal gyrus (BA 34)
3.85 / 38 / -42 / -10 / Right limbic lobe, parahippocampal gyrus (BA 19)
3.84 / 38 / -36 / -10 / Right limbic lobe, parahippocampal gyrus (BA 37)
3.51 / 56 / -26 / -12 / Right temporal lobe, middle gyrus (BA 21)
3.21 / 48 / -26 / -16 / Right temporal lobe, inferior gyrus (BA 20)
0.052 / 792 / 4.09 / 32 / 16 / -30 / Right temporal lobe, superior gyrus (BA 38)
0.503 / 98 / 3.53 / 38 / 22 / 14 / Right insula (BA 13)
0.407 / 152 / 3.44 / 28 / 26 / 52 / Right frontal lobe, middle gyrus (BA 8)
BA: Broadmann Area, cor: corrected

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