All the data was analysed statistically with Stata 11.2 and presented in frequency percentage. Chi square trend test was applied to see the change of ICU mortality, hand hygiene and bundle compliance with reference to year. P value <0.05 was considered as statistically significant.

Ventilator bundle compliance rate and hand hygiene rate were found to increase continuously over three years.Percentage increase in bundle compliance in SICU was only 2% (79.9% in 2011; 82.4% in 2014); (p=0.21)but that in NICU was 19%(67% in 2011; 83.2% in 2014)(p=0.01). Similarly, percentage increase in hand hygiene rate in NICU and SICU was 12% (61.4% in 2011; 64.6% in 2014) (p=0.285)and 5.5% (56.4% in 2011; 64.1% in 2014)(p=0.01)respectively. Thus, the percentage increase in the bundle compliance rate and hand hygiene rate was not statistically significant in the surgical ICU while the rate of increase was significant in the neurosurgical ICU.

VAP rate was found to be high (13.4 and 17.6 per thousand ventilator days in SICU and NICUrespectively) in the year 2011.However, with the intensive preventive efforts, VAP rate decreased by 68% in NICU and by 56% in SICU. The total number of VAP episodes was found to remain the same (n=22) in the surgical ICU between year 2011 and 2014 with p=0.64 which was not significant. However, there was a substantial reduction in the number of VAP episodes from 78 in 2011 to 28 in 2014; p=0.001; statistically significant. Similarly the reduction in the ICU mortality rate between 2011 and 2014 was not significant for surgical ICU (p=0.115); but was statistically significant for neurosurgical ICU (p=0.002). Thus, it can be concluded that the neurosurgical ICU showed better adherence to all the components of quality improvement process and thus had a better outcome for all the parameters when compared with surgical ICU.