1

William Y Song

CURRICULUM VITAE

William Y. Song, PhD, DABR

UPDATED:05.20.2011

ADDRESS:OfficeHome

Dept. Radiation Oncology5260 Fiore Terrace, APT-302

MooresCancerCenterSan Diego, CA92122

University of California, San DiegoUSA

3855 Health Sciences Dr., #0843

La Jolla, CA92093-0843

USA

TEL:W) 858-246-0886C) 858-337-0627F) 858-822-5568

EMAIL:

BIRTH PLACE:September 23, 1977, Seoul, Republic of (South) Korea

CITIZENSHIP:Canadian

LANGUAGES:English, Korean

ACADEMIC EDUCATION AND TRAINING (4)

1)B.Sc. [09/1996 – 04/2001, took ½ year off traveling].

Department of Physics and Astronomy,

University of Calgary, Calgary, Alberta, Canada

2)M.Sc. [09/2001 – 08/2003].

Department of Medical Physics (CAMPEP-Accredited Graduate Program),

Tom Baker Cancer Centre,

University of Calgary, Calgary, Alberta, Canada

Thesis title:Precision radiotherapy in the presence of geometric uncertainties: a Monte Carlo simulation.

Supervisor(s): Dr. Peter Dunscombe.

3)Ph.D. [09/2003 – 08/2006].

Department of Medical Biophysics,

London Regional Cancer Program,

University of WesternOntario, London, Ontario, Canada

Thesis title:Evaluation and mitigation of geometric uncertainties in prostate cancer radiation therapy through image guidance.

Supervisor(s): Dr. Jake Van Dyk, Dr. Jerry Battista.

4)(CAMPEP-Accredited) Medical Physics Residency [10/2006 – 09/2008].

CAMPEP-Accredited Medical Physics Residency Training Program,

Department of Radiation Oncology,

DavisCancerCenter,

University of Florida, Gainesville, Florida, USA

Clinical Supervisor(s): Dr. Jatinder Palta, Dr. Jonathan Li.

PROFESSIONAL ACCREDITATION (1)

1)American Board of Radiology (ABR) – Therapeutic Radiologic Physics

ABR ID: P5066, Effective 6.30.2010 – 6.30.2020

ACADEMIC APPOINTMENTS AND WORK EXPERIENCE (2)

1)Assistant Professor

[11/01/08 –Present]

Department of Radiation Oncology

University of CaliforniaSan Diego (UCSD)

Rebecca and JohnMooresComprehensiveCancerCenter

2)Adjunct Professor

[06/26/09 – Present]

Department of Physics

San DiegoStateUniversity (SDSU)

GRADUATE STUDENTS& RESEARCH FELLOWS(7)

1)Tyler Watkins, MSc – Primary Supervisor

[1/13/09 – 6/30/10]

Research Fellow, University of CaliforniaSan Diego

Project: 4DCT uncertainties in lung cancer target definition

2)ChunjooPark – Primary Supervisor

[10/01/09 – Present]

PhD Thesis Research, University of CaliforniaSan Diego

Project: CBCT image reconstruction using iterative algorithms

3)Ammar Durghalli – Primary Supervisor

[6/08/09 – Present]

MSc Thesis Research, San DiegoStateUniversity

Project: Four-dimensional treatment planning of lung cancer using Demons & optical flow deformable image registration algorithms

4)Matt Webster – Primary Supervisor

[5/17/10 – Present]

PhD Thesis Research, University of CaliforniaSan Diego

Project: Development of a robotics-guided dynamic modulated brachytherapy (DMBT) system for rectal cancer

5)Kevin Kauweloa – Primary Supervisor

[10/13/09 – Present]

MSc Thesis Research, San DiegoStateUniversity

Project: Motion effects in 4DCT

6)Brian Loughery – Primary Supervisor

[2/4/11 – Present]

MSc Thesis Research, San DiegoStateUniversity

Project: Deformable image registration algorithms for CT-CBCT registration

7)Angelo Bergamo – Primary Supervisor

[4/25/11 – 4/31/12]

Research Fellow, San DiegoStateUniversity

Project: Brachytherapy of Rectal Cancers

PROFESSIONAL MEMBERSHIPS (5)

1)Radiological Society of North America (RSNA)

[02/2010 - Present]

Full Member

2)American Society of Therapeutic Radiology and Oncology (ASTRO)

[04/2009 – Present]

Associate Member

3)Southern California Chapter, American Association of Physicists in Medicine (SCC-AAPM)

[12/2008 – Present]

Full Member

4)American Association of Physicists in Medicine (AAPM)

[05/2007 – Present]

Full Member

5)Korean-American Medical Physicists in North America (KAMPiNA)

[05/2007 – Present]

Full Member, Secretary of Academic Affairs [2010-2011]

ACADEMIC COMMITTEES AND PROFESSIONAL ACTIVITIES (3)

1)Secretary of Academic Affairs [08/2009 – 08/2011]

Korean American Medical Physicists in North America (KAMPiNA)

2)Academic member [06/2010 – 10/2013]

University of CaliforniaSan Diego

Academic Senate Committee: Human Exposure Review Committee (HERC), a sub-committee of Radiation Safety and Surveillance Committee (RSSC)

3)Assistant Program Director of Resident Progress [07/2010 – Present]

Medical Physics Residency Program, Department of Radiation Oncology,

University of CaliforniaSan Diego

ACADEMIC JOURNAL REVIEWER (7)

1)Ad hoc reviewer for the International Journal of Radiation Oncology, Biology, and Physics, (2006 – Present).

2)Ad hoc reviewer/associate editor for the Medical Physics Journal, (2006 – Present).

3)Ad hoc reviewer for the Radiotherapy and Oncology, (2008 – Present).

4)Ad hoc reviewer for the Journal of Applied Clinical Medical Physics, (2009 – Present).

5)Ad hoc reviewer for the Physics in Medicine and Biology Journal, (2009 – Present).

6)Ad hoc reviewer for the Practical Radiation Oncology (2010 – Present).

7)Ad hoc reviewer for the Sensors Journal (2010 – Present).

RESEARCH GRANTS (4)

1)Song WY (PI).High Performance Computational Tool for Image-Guided Radiation Therapy of Lung Cancer. American Cancer Society (ACS) Intramural Research Grant, 2009. Total: $30,000US (09/01/09 – 10/31/10).

2)Song WY (Co-PI).Four-dimensional liver imaging verification for external-beam radiotherapy (4D-LIVER): Phase I study. Varian Medical Systems Inc. Research Grant. Total: $82,941US (06/01/10 – 05/31/11).

3)Song WY (Co-PI).Development of the next generation of intelligent radiation therapy planning system. Nuclear Research & Development Program of National Research Foundation of Korea (NRF) Grant No. 2011-0001851. Total: $385,000US (03/01/11 – 02/29/12).

4)Song WY (PI). Development of novel 4D imaging framework for liver cancer radiation therapy. Clinical and Translational Research Institute (CTRI) – Pilot Innovative Technology Grant, 2011. Total: $40,000US (05/23/11 – 03/31/12).

BOOKS ANDCHAPTERS (4)

1)Song WY (sole author). Image-Guided Radiation Therapy of Prostate Cancer. Publisher: VDM publishings, Germany (2009)

2)Song WY and Bissonnette JP. Chapter: MV and kV in-room imagers. Quality & Safety in Radiotherapy. Editors: T Pawlicki, P Dunscombe. Publisher: Taylor & Francis, USA (2011)

3)Song WY and Kamath S. Chapter: “Kilovoltage Systems,” IGRT: A Clinical Perspective. Editors: AJ Mundt, JC Roeske. (2011)

4)Mell LK and Song WY.Chapter: “Daily Cone Beam Computed Tomography for Perivesicular Recurrence of Non-Hodgkin’s Lymphoma,” IGRT: A Clinical Perspective. Editors: AJ Mundt, JC Roeske. (in press 2011)

PATENTS (2)

1)Song WY, Scanderbeg D, Watkins WT, Webster M, Stenstrom J, Lawson J. Brachytherapy applicator with a dynamic shielding.(filed: 9.22.2010).

2)Song WY, Park C, Song B. Fast, iterative, image reconstruction using a gradient projection algorithm employing Barzilai-Borwein step size: Application to CT, CBCT, DTS, PET, SPECT, and MRI reconstruction. (filed: 3.18.2011).

PUBLICATIONS IN PEER-REVIEWED JOURNALS (25)

1)Song WY and Dunscombe P. EUD based margin selection in the presence of set-up uncertainties. Med Phys 2004;31:849-859.

2)Song WY, Battista J, and Van Dyk J. Limitations of a convolution method for modeling geometric uncertainties in radiotherapy: the radiobiological dose-per-fraction effect. Med Phys 2004;31:3034-3045.

3)[On Cover Page of Medical Physics Journal, July 2005] Song WY, Schaly B, Bauman G, Battista J, and Van Dyk J. Image-guided adaptive radiation therapy (IGART): Radiobiological and dose escalation considerations for localized carcinoma of the prostate. Med Phys 2005;32:2193-2203.

4)Schaly B, Bauman G, Song WY, Battista J, and Van Dyk J. Dosimetric impact of image-guided 3-D conformal radiation therapy of prostate cancer. Phys Med Biol 2005;50:3083-3101.

5)Ploquin N, Song WY, Lau H, and Dunscombe P. Intensity modulated radiation therapy for oropharyngeal cancer: the sensitivity of plan objectives and constraints to set-up uncertainty. Phys Med Biol 2005;50:3515-3533.

6)Song WY, Schaly B, Bauman G, Battista J, and Van Dyk J. Evaluation of image-guided radiation therapy (IGRT) technologies and their impact on the outcome of hypofractionated prostate cancer treatments: a radiobiological analysis. Int J Radiat Oncol Biol Phys 2006;64:289-300.

7)Song WY, Chiu B, Bauman G, Rodrigues G, Lock M, Ash R, Lewis C, Fenster A, Battista J, Van Dyk J. Prostate contouring uncertainty in mega-voltage computed tomography (MVCT) images acquired with a helical tomotherapy unit during image-guided radiation therapy (IGRT). Int J Radiat Oncol Biol Phys 2006;65:595-607.

8)Song WY, Wong E, Bauman G, Battista J, Van Dyk J. Dosimetric evaluation of daily rigid and non-rigid geometric correction strategies during on-line image-guided radiation therapy (IGRT) of prostate cancer. Med Phys 2007;34:352-365.

9)Song WY, Kamath S, Ozawa S, Alani S, Chvetsov A, Bhandare N, Palta J, Liu C, Li J. A dose comparison study between XVI and OBI CBCT systems. Med Phys 2008;35:480-486.

10)Jia X, Lou Y, Li R, Song WY, Jiang SB. GPU-based fast cone beam CT reconstruction from undersampled and noisy projection data via total variation. Med Phys 2010;37:1757-1760.

11)Lewis JH, Li R, Watkins WT, Lawson J, Cervino LI, Song WY, Jiang SB. Markerless lung tumor tracking and trajectory reconstruction using rotational cone-beam projections: a feasibility study. Phys Med Biol 2010;55:2505-2522.

12)Watkins WT, Li R, Lewis J, Park JC, Sandhu A, Jiang SB, Song WY [corresponding author]. Patient-specific motion artifacts in 4DCT. Med Phys2010;37(6):2855-2861.

13)Youn HB, Kim JS, Cho MK, Jang SY, Song WY, Kim HK. Optimizing imaging conditions in digital tomosynthesis for image-guided radiation therapy. Kor J Med Phys 2010;21(3):281-290.

14)Song WY, Huh SN, Liang Y, White G, Nichols RC, Watkins WT, Mundt AJ, Mell LK. Dosimetric comparison study between intensity modulated radiation therapy and three-dimensional conformal proton therapy for pelvic bone marrow sparing in the treatment of cervical cancer. J App Clin Med Phys 2010;11(4):83-92.

15)Park JC, Park SH, Kim JS, Han Y, Ju SG, Shin E, Shin JS, Park HC, Ahn YC, Song WY[corresponding author]. Digital tomosynthesis for patient alignment system using half-fan mode CBCT projection images. Kor J Med Phys 2010;21(4):360-366.

16)Nath SK, Sandhu AP, Kim D, Bharne A, Nobiensky PD, Lawson JD, Fuster M, Bazhenova L, Song WY, Mundt AJ. Frameless Image-Guided Stereotactic Body Radiation Therapy for Lung Tumors with 4DCT or 4DPET/CT. Clin Lung Canc (in press, 2011).

17)Nath SK, Sandhu AP, Kim D, Bharne A, Nobiensky PD, Lawson JD, Fuster M, Bazhenova L, Song WY, Mundt AJ. Locoregional and distant failure following image-guided stereotactic body radiation for early-stage primary lung cancer. Radiother Oncol2011;99(1):12-17.

18)Kamath S, Song WY, Chvetsov A, Ozawa S, Lu H, Samant S, Liu C, Li J, Palta J. An image quality comparison study between XVI and OBI CBCT systems. J App Clin Med Phys 2011;12(2):376-390.

19)Moiseenko V, Song WY, Mell LK, Bhandare N. A comparison of dose-response characteristics of four NTCP models using outcomes of radiation-induced optic neuropathy and retinopathy. Rad Onc J (in review 2011).

20)Bhandare N, Moiseenko V, Song WY, Morris C, Bhatti MT, Mendenhall WM. Dry-eye syndrome after radiation therapy for head and neck tumors. Int J Radiat Oncol Biol Phys (in review, 2011).

21)Jia X, Lou Y, Lewis J, Li R, Gu X, Men C, Song WY, Jiang SB. GPU-based fast low-dose cone beam CT reconstruction via total variation. J X-Ray Sci Tech (in press 2011).

22)Park JC, Kim HK, Song WY, Achterkirchen T, Lee HK. Defective pixel map creation based on wavelet analysis in digital radiography detectors. Nucl Instrand Meth A 2011;634(1):101-105.

23)Li R, Lewis J, Jia X, Gu X, Folkerts M, Men C, Song WY, Jiang SB. 3D tumor localization through real-time volumetric x-ray imaging for lung cancer radiotherapy. Med Phys 2011;38(5):2783-2794.

24)Park JC, Park SH, Kim JS, Han Y, Cho MK, Kim HK, Liu Z, Jiang SB, Song B, Song WY [corresponding author]. Ultra-fast digital tomosynthesis reconstruction using general-purpose GPU programming for image-guided radiation therapy. Tech Cancer Res & Treat (in press 2011).

25)Park JC, Park SH, Kim JH, Yoon SM, Kim SS, Kim JS, Liu Z, Watkins WT, Song WY [corresponding author]. Four-dimensional cone-beam computed tomography and digital tomosynthesis reconstructions using respiratory signals extracted from transcutaneously inserted metal markers for liver SBRT. Med Phys 2011;38(2):1028-1036.

PEER-REVIEWED CONFERENCE ABSTRACTS (66)

1)Choi D, Chen A, Dirske C, Song WY. Prediction of isocentre displacement using depth helmet in fractionated stereotactic radiotherapy (FSRT). Med Phys (Abstract) 2002;29:1252. AAPM/COMP, Montreal (2002).

2)Wu J, Breitman K, Song WY. Estimation of dose constraints using biologically-normalized dose-volume histograms (BN-DVH) for hypofractionated radiotherapy in the treatment of prostate cancer. ESTRO/ECCO, Copenhagen (2003).

3)Song WY, Dunscombe P. EUD based margin selection: a simulation including a target, critical organ, and set-up uncertainties. Med Phys (Abstract) 2003;30:1506. AAPM, San Diego, USA (2003).

4)Song WY, Dunscombe P. The trade-off between margins and prescribed doses using the Equivalent Uniform Dose: a phantom study. COMP Conference Proceedings 2003;49:28-30. COMP, Edmonton (2003).

5)Song WY, Battista J, Van Dyk J. Limitations of a convolution method for modeling geometric uncertainties in radiotherapy: the biological dose-per-fraction effect. 3rd place finish in the Young Investigators’ Symposium (YIS): COMP, Winnipeg (2004).

6)Song WY, Battista J, Van Dyk J. Limitations of a convolution method for modeling geometric uncertainties in radiotherapy: the biological dose-per-fraction effect. Annual Oncology Day, University of Western Ontario, London, Ontario (2004).

7)Schaly B, Bauman G, Song WY, Battista J, Van Dyk J. Dosimetric impact of geometric adaptive radiation therapy. Young Investigators’ Symposium (YIS): AAPM Great Lakes Chapter, London, Ontario (2004).

8)Song WY, Schaly B, Battista J, Van Dyk J. Dose escalation with image-guided adaptive radiation therapy (IGART) for localized carcinoma of the prostate. Young Investigators’ Symposium (YIS): AAPM Great Lakes Chapter, London, Ontario (2004).

9)Ploquin N, Song WY, Lau H, Dunscombe P. Effect of position uncertainties on dose distribution in intensity modulated radiation therapy (IMRT). Radiother Oncol (Abstract) 2004;72:S53. CARO, Halifax (2004).

10)Ploquin N, Song WY, Lau H, Dunscombe P. Set-up uncertainties of an oropharyngeal IMRT plan. (Abstract) ACB annual meeting, Banff (2004).

11)Ploquin N, Song WY, Lau H, Dunscombe P. Sensitivity of objectives and constraints of an IMRT plan to patient set-up uncertainty. WESCAN, Calgary, Alberta (2005).

12)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. Iso-NTCP dose escalation with image-guided adaptive radiation therapy (IGART) for localized carcinoma of the prostate. CIHR and NCIC - Cancer Research Across the Spectrum: National Meeting for Trainees, Mont Tremblant, Quebec (2005).

13)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. Image-guided adaptive radiation therapy (IGART): radiobiological and dose escalation considerations for localized carcinoma of the prostate. Annual Oncology Day, University of Western Ontario, London, Ontario (2005).

14)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. Iso-NTCP dose escalation with image-guided adaptive radiation therapy (IGART) for localized carcinoma of the prostate. Med Phys (Abstract) 2005;32:1935. AAPM, Seattle, USA (2005).

15)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. Evaluation of image-guided radiation therapy (IGRT) technology and its impact on the outcome of hypofractionated prostate cancer treatments - a radiobiological analysis. Med Phys (Abstract) 2005;32:1898-1899. AAPM, Seattle, USA (2005).

16)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. On-line image-guided adaptive radiation therapy (IGART) of the prostate: a retrospective analysis using iso-NTCP dose escalation. OCITS, Toronto, Canada (2005).

17)Song WY, Schaly B, Bauman G, Battista J, Van Dyk J. Evaluation of image-guided radiation therapy (IGRT) technologies and their impact on the outcome of hypofractionated prostate cancer treatments - a radiobiological analysis. Young Investigators’ Symposium (YIS): AAPM Great Lakes Chapter, Birmingham, Michigan, USA (2005).

18)Song WY, Wong E, Bauman G, Battista J, Van Dyk J. Dosimetric evaluation of geometric correction strategies for on-line image-guided radiation therapy (IGRT) of prostate cancer. Annual Oncology Day, University of Western Ontario, London, Ontario (2006).

19)Song WY, Chiu B, Bauman G, Lock M, Rodrigues G, Ash R, Lewis C, Fenster A, Battista J, Van Dyk J. Prostate contouring uncertainty in mega-voltage computed tomography (MVCT) images acquired with a helical tomotherapy unit during image-guided radiation therapy (IGRT). Annual Oncology Day, University of Western Ontario, London, Ontario (2006).

20)Song WY, Chiu B, Bauman G, Lock M, Rodrigues G, Ash R, Lewis C, Fenster A, Battista J, Van Dyk J. Prostate contouring uncertainty in mega-voltage computed tomography (MVCT) images acquired with a helical tomotherapy unit during image-guided radiation therapy (IGRT). AAPM, Orlando, USA (2006).

21)Song WY, Wong E, Bauman G, Battista J, Van Dyk J. Dosimetric evaluation of daily rigid and non-rigid geometric correction strategies during on-line image-guided radiation therapy (IGRT) of prostate cancer. AAPM, Minneapolis, USA (2007).

22)Ozawa S, Song WY, Alani S, Liu C, Karasawa K, Palta J, Li J. Compatibility of IMRT plans for the matched beam linear accelerators. AAPM, Minneapolis, USA (2007).

23)Song WY, Ozawa S, Alani S, Liu C, Chvetsov A, Bhandare N, Palta J, Li J. Daily patient dose from kilo-voltage cone-beam computed tomography: A comparison between XVI and OBI. AAPM, Minneapolis, USA (2007).

24)Alani S, Song WY, Ozawa S, Amdur R, Olivier K, Liu C, Li J. Evaluation of intra-fractional patient movement during image-guided stereotactic body radiation therapy of spine and lung patients. ASTRO, Los Angeles, USA (2007).

25)Bhandare N, Song WY, Malyapa R, Bhatti MT, Mendenhall WM. Evaluation of effects of fractionation in radiation-induced optic neuropathy and retinopathy after external-beam radiation therapy for head and neck cancers. ASTRO, Los Angeles, USA (2007).

26)Ozawa S, Song WY, Alani S, Liu C, Li J. Evaluation of inter-fractional setup reproducibility based on skin markers for the treatment of prostate cancer. ASTRO, Los Angeles, USA (2007).

27)Song WY, Bhandare N, Moiseenko V. Dose response analysis of radiation-induced optic neuropathy (RION) single-institution data using the Lyman NTCP model. AAPM, Houston, USA (2008).

28)Song WY, Bhandare N, Moiseenko V. Dose response analysis of radiation-induced retinopathy (RIRP) single-institution data using the Lyman NTCP model. AAPM, Houston, USA (2008).

29)Kamath S, Song WY, Chvetsov A, Ozawa S, Liu C, Li J, Palta J. An image quality comparison study between XVI and OBI CBCT systems. AAPM, Houston, USA (2008).

30)Ozawa S, Peng J, Song WY, Kamath S, Kurokawa C, Liu C, Palta J, Karasawa K, Li J. Comprehensive evaluation of the bow-tie filter in the XVI CBCT system. AAPM, Houston, USA (2008).

31)Ozawa S, Lu B, Song WY, Kurokawa C, Chvetsov A, Palta J, Liu C, Karasawa K, Li J. Evaluation of rectal balloon reproducibility for prostate radiation therapy using cone beam CT. ASTRO, Boston, USA (2008).

32)Bhandare N, Song WY, Moiseenko V, Malyapa R, Mendenhall W. Radiation-induced optic neuropathy: Modeling total dose and fractionation. ASTRO, Boston, USA (2008).

33)Cerviño L, Song WY, Wang J, Lawson J, Pawlicki T, Jiang S. Feasibility study of frame-less mask-less bite-block-less stereotactic radiosurgery treatment with real-time surface imaging. AAPM, Anaheim, USA (2009).

34)Lewis J, Li R, Watkins W, Cerviño L, Lawson J, Song WY, Jiang S. Markerless Lung Tumor Tracking in Rotational Radiotherapy. AAPM, Anaheim, USA (2009).

35)Gu J, Song WY, Xu XG. Monte Carlo Based kV CBCT Modeling and Dose Calculations Involving Anatomical Phantom. AAPM, Anaheim, USA (2009).

36)Bhandare N, Song WY, Moiseenko V, Mendenhall W. Dose-response analysis of radiation-induced sensory neural hearing loss. AAPM, Anaheim, USA (2009).

37)Kamath S, Song WY, Li J, Palta J. Efficient registration of dose distributions. AAPM, Anaheim, USA (2009).

38)Watkins W, Lewis J, Li R, Jiang S, Song WY.Uncertainty in GTV and ITV Delineation with 4DCT Imaging. AAPM, Anaheim, USA (2009).

39)Bhandare N, Song WY, Moiseenko V, Mendenhall W. Outcome analysis of radiation induced sensory neural hearing loss. ASTRO, Chicago, USA (2009).

40)Song WY, Huh S, Liang Y, White G, Yashar C, Mundt A, Mell L. Dosimetric comparison study between intensity modulated X-ray therapy (IMXT) and three-dimensional conformal proton therapy (3DCPT) for treatment of cervical cancers. ASTRO, Chicago, USA (2009).

41)Cervino LI, Song WY, Wang JZ, Lawson J, Murphy K, Pawlicki T, Jiang SB. Frame-less mask-less bite-block-less stereotactic radiosurgery treatment with real-time surface imaging: a phantom and volunteer study. ASTRO, Chicago, USA (2009).