NDA Project Full Title: Healthy Ageing Across the Life Course (Halcyon Project)
HALCyon
NDA project full title: Healthy Ageing Across the Life Course (HALCyon Project)
PI: Diana Kuh
Publications
Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C , Deary IJ , Elliott J, Gunnell D, Harris SE , Kumari M, Kivimaki M, Martin R , Power C, Aihie Sayer A , Starr JM , Kuh D, Day INM and the HALCyon study team. Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme. Aging Cell 2011, 10(3): 520-532, epub ahead of print.
Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C, Deary IJ, Gunnell D, Harris SE, Kumari M, Martin R, Moran CN, Pitsiladis YP, Ring SM, Aihie Sayer A, Davey Smith G, Starr JA, Kuh D, Day INM and the HALCyon study team. ACTN3 genotype, athletic status and life course physical capability: meta-analysis of the literature and nine studies. Human Mutation 2011, doi: 10.1002/humu.21526, epub ahead of print.
Birnie K, Cooper R, Martin RM, Kuh D, Aihie Sayer A, Alvarado BE, Bayer A, Christensen K, Cho S, Cooper C, Corley J, Craig L, Deary IJ, Demakakos P, Ebrahim S, Gallacher J, Gow AJ, Gunnell D, Haas S, Hemmingsson T, Inskip H, Jang S, Noronha K, Osler M, Palloni A, Rasmussen F, Santos-Eggimann B, Spagnoli J, Starr J, Steptoe A, Syddall H, Tynelius P, Weir D, Whalley LJ, Zunzunegui MV, Ben-Shlomo Y, Hardy R on behalf of the HALCyon study team. Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS ONE 2011; 6(1):e15564.
Birnie K, Martin RM, Gallacher J, Bayer A, Gunnell D, Ebrahim S, Ben-Shlomo Y. Socio-economic disadvantage from childhood to adulthood and locomotor function in old age: a lifecourse analysis of the Boyd Orr and Caerphilly prospective studies. Journal ofEpidemiology and Community Health2011 Nov;65(11):1014-23. doi: 10.1136/jech.2009.103648 (associated HALCyon publication).
Cooper R, Mishra GD, Kuh D. Physical activity across adulthood and physical performance in midlife. American Journal of Preventive Medicine 2011; 41(4):376-384.
Cooper R, Huisman M, Kuh D, Deeg DJH. Do positive psychological characteristics modify the associations of physical performance with functional decline and institutionalisation? Findings from the Longitudinal Aging Study Amsterdam. Journal of Gerontology: Social Sciences 2011; 66:468-477.
Cooper R, Kuh D, Cooper C, Gale CR, Lawlor DA, Matthews F, Hardy R and the FALCon and HALCyon study teams. Objective measures of physical capability and subsequent health: a systematic review. Age and Ageing 2011; 40:14-23.
Cooper R, Kuh D, Hardy R and the Mortality Review Group on behalf of the FALCon and HALCyon study teams. Objectively measured physical capability levels and mortality: a systematic review and meta-analysis. BMJ 2010, 341:c4467.
* Press releases were prepared for the publication of the physical capability and mortality review published in the British Medical Journal and time was spent communicating the findings to a number of journalists. The paper received wide news coverage and was reported in national newspapers, including the Independent, Guardian and Daily Mail, radio news reports and internationally on internet news sites.
Cooper R, Hardy R, Aihie Sayer A, Ben-Shlomo Y, Birnie K, Cooper C, Craig L, Deary IJ, Demakakos P, Gallacher J, McNeill G, Martin RM, Starr JM, Steptoe A and Kuh D on behalf of the HALCyon study team. Age and gender differences in physical capability levels from mid-life onwards: the harmonisation of data from eight UK cohort studies
PLoS One 2011;6(11):e27899.
Gale C, Dennison E, Cooper C, Aihie Sayer A. Neighbourhood environment and positive mental health in older people: the Hertfordshire Cohort Study. Health and Place 2011 Jul;17(4):867-74. Epub 2011 May 13(associated HALCyon publication).
Gale, CR,Aihie Sayer A, Cooper C, Dennison E, Starr J, Whalley L, Gallacher J, Ben-Shlomo Y, Kuh D, Hardy R, Craig L, Deary IJ and the HALCyon study team. Factors associated with symptoms of anxiety and depression in five cohorts of community-based older people: the HALCyon (Healthy Ageing across the Life Course) Programme Psychological Medicine 2011, 24:1-17, epub ahead of print.
Gale CR, Deary IJ, Kuh D, Huppert FA, Richards M. Neuroticism in adolescence and cognitive function in mid life in the British 1946 birth cohort: the HALCyon programme. Journal of Gerontology: Psychological Science 65B, 2010, 50-6.
Gale CR,Allerhand M, Aihie Sayer A, Cooper C, Dennison E, Starr J, Ben-Shlomo Y, Gallacher J, Kuh D, Deary IJ. The structure of the Hospital Anxiety and Depression Scale in four cohorts of community-based, healthy older people. International Psychogeriatrics 2010, 22:559-71.
Gardner M, Lightman S, Gallacher J, Hardy R, Kuh D, Ebrahim S, Bayer T, Ben-Shlomo Y. Diurnal cortisol patterns are associated with physical performance in the Caerphilly Prospective Study (CaPS).International Journal of Epidemiology.2011 Jul 14. [Epub ahead of print]
Kuh D, NDA Preparatory Network. Unconventional views of frailty. Guest editorial. A life course approach to healthy aging, frailty, and capability. Journal of Gerontology (Medical Sciences). 2007;62A:717-721.
Mishra G, Gale C, Aihie Sayer A, Cooper C, Dennison E, Whalley L, Craig L, Kuh D, Deary I. How useful are the SF-36 subscales in older people: Mokken scaling of data from the HALCyon Programme.Quality of Life Research 2011, doi: 10.1007/s11136-010-9838-7, epub ahead of print.
Mulla U, Mishra GD, Richards M, Prynne CJ, Stephen AM and the HALCyon team. Major fruits as a common marker in cross-cohort analysis using dietary data acquired through different instruments. Annals of Nutrition & Metabolism 2009; 55 Supp 1:601 (abstract).
Murray ET, Strand BH, hardy R, Cooper R, Guralnik J, Kuh D. Gender and life course socioeconomic differences in trajectories of functional limitations in midlife: findings from the 1946 British birth cohort. Journal of Gerontology (Medical Sciences) 2011, Aug 22 doi:10.1093/Gerona/grl139
Strand BH, Cooper R, Hardy R, Kuh D and Guralnik JM. Lifelong socioeconomic position and physical performance in midlife: Results from the British 1946 birth cohort. European Journal of Epidemiology 2011; 26(6):475-483.
In press
Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C , Deary IJ, Gaunt TR, Gunnell D, Harris SE , Kumari M, Martin RM, Aihie Sayer A , Starr JM,Kuh D,NM Day INM and the HALCyon study team
A multi-cohort study of polymorphisms in the GH/IGF-1 axis and physical capability: the HALCyon programme
PLoS One
Dodds R, Denison HJ, Ntani G, Cooper R, Cooper C, Sayer AA and Baird J. Birth weight and muscle strength: a systematic review and meta-analysis.Journal of Nutrition, Health and Aging
Gow A, Johnson W, Mishra G, Richards M, Kuh D, Deary I. Is age kinder to the initially more able?: Yes, and no. Intelligence
Murray ET, Ben-Shlomo Y, Hardy R, Aucott P, Tilling K, Kuh D, Southall H. Advantages and difficulties in examining associations of area exposures over the life course and capability: the HALCyon project. Health and Place
Under revision /Under review /Submitted
Gale C, Allerhand M, Deary I and the HALCyon Study Team.Depressive symptoms are associated with cognitive ability but not with age-related cognitive decline: the English Longitudinal Study of Ageing. Psychological Medicine – under revision.
Kuh D, Cooper R, Richards M, Gale C, von Zglinicki T, Guralnik J. A life course approach to healthy ageing: the HALCyon programme. Public Health. Special edition of World Congress of Epidemiology.
Parsons S,Elliott, J, Gale, C, Kuh, D
What are the advantages and disadvantages of being the age you are?" Perceptions of older age by men and women in two British cohorts.
Gale C, Allerhand M, Deary I and the HALCyon Study Team.
Determinants of the trajectories of cognitive decline and depressive symptoms in older people.
Forthcoming HALCyon associated book
Kuh D et al. co-edited book for Oxford University Press on ‘A life course approach to healthy ageing’
A book proposal has been approved by Oxford University Press which will be suitable for all users and that will set the findings, and the likely impact of these findings, from the HALCyon programme in their wider context. Summary articles and briefing reports, based on the book, will attempt to achieve even wider circulation as well as a preconference meeting at the Society for Social Medicine annual conference in September 2012.
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