Intravenous Immuniglobulin Therapy (IVIG)

Skill: /

Intravenous Immuniglobulin Therapy (IVIG)

Area of Practice: /

Neuroscience Care Induction Skills

Module and Status /

Current Perspectives in Neuroscience NW304

Level: / 3
Author/date of origin: / Mike Blunt – May 2004
Author/date of review:
Time estimate: / 1 hour
Knowledge required related to skill(should know):

Demonstrates basic understanding of human immune process and passive/active immunity.
Demonstrate awareness of need for immune globulin therapy /replacement.
Identify types of neuro-patient who may need or benefit from immunoglobulin therapy.
Critically evaluate the side effects/risks of blood product therapy (sensitivity/allergic/ delayed/febrile reactions – and their symptoms)
Discuss how to manage possible reactions to IVIG therapy (incl. airway, anaphylaxis and extravasation management).

Identify the equipment (incl. filter size) used in IVIG therapy.
Discuss observations required pre/during/ post infusion – give rationale.
Awareness of checking weight and taking bloods (incl. tests required) before commencement of therapy – give rationale.
Critically discusses why initial serum check for anti-IgA is necessary.
Rationale for need of dedicated cannula.
If BM measuring required, discuss possible problem with blood glucose monitoring equipment (BM) – MDA alert.

Practice descriptor, i.e. can demonstrate skill used stating knowledge base and act appropriately at this level:

Prevention of infusion-reaction/management of same (incl. anaphylaxis).
Aware of possible physiological changes through sensitivity reactions to IVIG – able to act appropriately and safely to changes.
Maintaining patient safety during and post infusion.
Follows guidelines/protocols for administration.
Recognises correct form of prescription – discussion with pharmacist as appropriate.
Provides suitable monitoring equipment.
Employs specialist equipment to administer infusion.
Aseptic technique is used during commencement and during infusion.

Giving set is dated and labeled as blood product.
Monitors TPR and allied observations and acts appropriately to changes.
Monitors fluid balance.
Aware of legal issues surrounding blood product administration – accountability/Noting of batch no. – give rationale for same
Aware of procedure(s) for reporting possible contaminated or ‘spoilt’ IVIG product.
Ability to explain therapy to patient.
Involve patient in own care / therapy by explaining side-effects and/or reaction signs so that patient can alert staff to possible sensitivity reactions immediately.
Correctly documents / records IVIG administration details (Medical and Nursing notes).