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Appendix 1

Extensive telephone interview

Date______Age______(years).

Name______

Address______

Participation number______

1. Hemiplegic migraine Yes No %

a. Motor aura 1 2 ____

Headachephase

b. Age of onset . Age at last attack :______year.

c. Lifetime number of migraine attacks 1 1

2 2-4

3 5-9

4 10-49

5 50-100

6 >100

d. migraine attacks within last year 1 0

2 1-6

3 7-12

4 13-24

5 25-36

6 >36

e. duration 1 <30 minutter

2 30 min - 4h

3 4 h - 24 h

4 24h - 72 h

5 3 days - 7 days

6 more than 7 days

Yes No

f. unilateral 1 2

g pulsating 1 2

h. moderate/severe intensity 1 2

i. aggravation by physical activity 1 2

j. nausea 1 2

k.vomiting 1 2

l. photophobia 1 2

m.phonophobia 1 2

Precipitating factors Yes No

n. headtraumas 1 2

o. angiography 1 2

p. other things______

2. Visual aura Yes No %

a. Visual aura 1 2

Are the visual disturbances

b. unilateral 1 2

c. gradually progressing 1 2

d. starting centrally 1 2

e. starting peripherally 1 2

f. scotoma 1 2

g. zig-zag line (fortification) 1 2

h. flikering 1 2

i. Perserved central vision 1 2

j. duration of the gradual development min.

k. duration of the visual aura min.

l. Headache occur prior after simultaneous

to the visual aura 1 2 3

m. time before/after 1 min. 2 min.

3. Sensory aura Yes No %

a.sensory aura 1 2

Are the sensory aura?

b. unilateral 1 2

c. gradually progressing 1 2

Do the sensory disturbances involve?

d. the face 1 2

e. the tongue 1 2

f. the hand 1 2

g. the arm 1 2

h. the foot 1 2

i. the leg 1 2

j. the body 1 2

k.succession of sensory disturbances:

l.gradual development of sensory disturbance min.

m.duration of the sensory disturbance min.

4. Motor aura yes No

Are the motor disturbances

a. unilateral 1 2

b. gradradually progressing 1 2

Do the motor disturbances involve?

Yes No

c. the face 1 2

d. the tongue 1 2

e. the hand 1 2

f. the arm 1 2

g. the foot 1 2

h. the leg 1 2

i. The body 1 2

j. Succession of motor disturbances: k.gradual development of motor disturbance min.

l.duration of motor disturbance min.

m.has there been at least two yes No

Hemiplegic attacks? 1 2

n.changing side location of hemiparesis

from attack to attack 1 2

o. If no,

hemiparesis located on the______(right/left)

headache located on the______(right/left)

5. Aphasia/speech disturbances Yes No %

a. Aphasia 1 2

b. Dominant hand 1 Højre 2 Venstre 3 Ambidexter

Speech/aphasic disturbances Yes No

c. Probl. articulating speech 1 2

d. Probl. finding the right words 1 2

e. Probl.in understanding what others

people say 1 2

f. Probl. in the production of language 1 2

g.duration of aphasia min.

6. Basilar symptoms Yes No %

a. Basilar/occipital symptoms 1 2

basilar/bilat occipital disturbances:

b. bilateral pareses/paresthesia 1 2

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Yes No

c. bilateral visual disturbances 1 2

d. dysarthria 1 2

e. vertigo 1 2

f. diplopia 1 2

g. tinnitus 1 2

h. reduced hearing 1 2

i. reduced consciousness 1 2

j. reduced balance 1 2

k. drop attacks 1 2

l. Crossed symptoms 1 2

m.switching from one side to the other 1 2

Succession of the aura phenomena

7. Cerebellar symptoms

Ataxia Yes No

a. paroxystic ataxia 1 2

b. permanent ataxia 1 2

If yes,

c. Is the ataxia stabil 1 2

d. Is the ataxia progressive 1 2

If yes, age of onset of ataxia______age(years).

8. Non-hemiplegic migraine with aura

Yes No %

a. non-hemiplegic migraine with aura 1 2 ____

Headache phase

b. age of onset . Age at last attack :______age/years.

c. lifetime no. of attacks 1 1

2 2-4

3 5-9

4 10-49

5 50-100

6 >100

d. migraine attacks within last year 1 0

2 1-6

3 7-12

4 13-24

5 25-36

6 >36

e. duration 1 <30 min

2 30 min - 4h

3 4h - 24h

4 24h - 72 h

5 3 days - 7 days

6 > 7 days

Yes No

f. unilateral 1 2

g. pulsating 1 2

h. moderate/severe intensity 1 2

i. Aggravation by physical activity 1 2

j. nausea 1 2

k. vomiting 1 2

l. Photophobia 1 2

m.phonophobia 1 2

9. Visual aura Yes No %

a. Visual aura 1 2

Visual disturbances

b. unilateral 1 2

c. gradually progressing 1 2

d. starting centrally 1 2

e. starting peripherally 1 2

f. scotoma 1 2

g. zig-zag line (fortification) 1 2

h. flickering 1 2

i. Perserved central vision 1 2

j. duration of the gradual development min.

k. duration of the visual aura min.

l. Headache occur prior after simultaneous

to the visual aura 1 2 3

m. time before/after 1 min. 2 min.

10. Sensory aura Yes No %

a. sensory aura 1 2

Sensory disturbances

b. unilateral 1 2

c. gradually progressing 1 2

Do the sensory disturbances involve?

d. the face 1 2

e. the tongue 1 2

f. the hand 1 2

g. the arm 1 2

h. te foot 1 2

i. the leg 1 2

j. the body 1 2

k. succession of the sensory aura:

l. duration of the gradual development min.

m. duration of the sensory aura min.

11. Aphasia/Speech disturbances Yes No %

a. aphasia 1 2

b. dominant hand 1 right 2 left 3 ambidexter

Aphasia/Speech disturbances due to Yes No

c. probl. articulating speech 1 2

d. probl. finding the right words 1 2

e. probl. in understanding what other

people say 1 2

f. probl. in the production of language 1 2

g. duration of the aphasia/speech disturbances min.

12. Migraine aura without headache

Yes No %

a. aura without headache 1 2

Headache phase

b.Age of onset age/years.Age of last attack______age/years.

c. Lifetime no. of attacks 1 1

2 2-4

3 5-9

4 10-49

5 50-100

6 >100

Aura disturbances Yes No

d. visual aura 1 2

e. sensory aura 1 2

31

Yes No

f. motor aura 1 2

g. Aphasia 1 2

h. Duration of the aura min.

13. Migraine without aura Yes No

a. migraine without aura 1 2

Headache phase

b. age of onset Years.Age at last attack_____age/years.

c. lifetime no. Of attacks 1 1

2 2-4

3 5-9

4 10-49

5 50-100

6 >100

d. migraine attacks within last year 1 0

2 1-6

3 7-12

4 13-24

5 25-36

6 >36

e. duration 1 <30 min

2 30 min - 4h

3 4 h - 24 h

4 24 h - 72 h

5 3 days -7 days

6 >7 days

Yes No

f. unilateral 1 2

g. pulsating 1 2

h. moderate/severe intensity 1 2

i. aggravation by physical activity 1 2

j. nausea 1 2

k. vomiting 1 2

l. Photophobia 1 2

m. phonophobia 1 2

14. Tension-type headache Yes No

a. Tension type headache 1 2

b. Age of onset (age/years).Age at last attack___(age/years).

Headache phase

c. headache days within last year 1 0

2 1-7

3 8-14

4 15-30

5 31-180

6 180 or more

d. duration 1 <30 min

2 30 min - 4 h

3 4 h - 24 h

4 24 h- 72 h

5 3 days - 7 days

6 >7 days

Yes No

e. bilateral 1 2

f. pressing 1 2

g. mild/moderate intensity 1 2

h. aggravation by physical activity 1 2

i. nausea 1 2

j. vomiting 1 2

k. photophobia 1 2

l. phonophobia 1 2

15. Other disorders Yes No

a. concussion 1 2

b. fractures of the skull 1 2

c. encephalitis 1 2

d. meningitis 1 2

e. cerebral ischemia 1 2

f. cerebral haemorrhagia 1 2

g. TIA 1 2

h. Arterial hypertension 1 2

i. Other 1 2

If yes, specify

j. Secondary headache 1 2

If yes, specify

Neuroimaging Yes No

k. CT-scan 1 2

If yes, when______year.

L. MR-scan 1 2

If yes, when______year.

16. Family history Yes No

a. proband adopted 1 2

b. other affected family members 1 2

If yes, specify who______

Pedigree drawing: