Supplementary Table 1. Genes Identified As Differentially Expressed Between Post-Treatment

Supplementary Table 1. Genes identified as differentially expressed between Post-treatment Failures and Complete Responders. ANOVA p≤0.05 and 1.5-fold cutoff.

RefSeq / Gene Symbol / Gene Name / Fold-Change
(P-t Fail vs. CR) / p-value
NM_032563 / LCE3D / late cornified envelope 3D / 12.78 / 3.40E-03
NM_207392 / KRTDAP / keratinocyte differentiation-associated protein / 5.68 / 1.46E-02
NM_006121 / KRT1 / keratin 1 / 4.36 / 2.91E-02
NM_144505 / KLK8 / kallikrein-related peptidase 8 / 3.08 / 2.24E-02
NM_002133 / HMOX1 / heme oxygenase (decycling) 1 / 2.99 / 1.79E-02
NM_032849 / C13orf33 / chromosome 13 open reading frame 33 / 2.86 / 1.38E-02
NM_005708 / GPC6 / glypican 6 / 2.82 / 2.53E-02
NM_002445 / MSR1 / macrophage scavenger receptor 1 / 2.66 / 2.23E-02
NM_002581 / PAPPA / pregnancy-associated plasma protein A, pappalysin 1 / 2.64 / 2.90E-03
NM_198148 / CPXM2 / carboxypeptidase X (M14 family), member 2 / 2.64 / 1.92E-02
NM_004041 / ARRB1 / arrestin, beta 1 / 2.63 / 2.38E-02
NM_004065 / CDR1 / cerebellar degeneration-related protein 1, 34kDa / 2.60 / 2.26E-02
NM_001184830 / VSIG4 / V-set and immunoglobulin domain containing 4 / 2.58 / 4.92E-02
NM_004791 / ITGBL1 / integrin, beta-like 1 (with EGF-like repeat domains) / 2.57 / 1.45E-02
NM_001785 / CDA / cytidine deaminase / 2.52 / 4.81E-02
NM_001135057 / LRRC15 / leucine rich repeat containing 15 / 2.46 / 1.56E-02
NM_017791 / FLVCR2 / feline leukemia virus subgroup C cellular receptor family, member 2 / 2.45 / 1.83E-02
NM_006988 / ADAMTS1 / ADAM metallopeptidase with thrombospondin type 1 motif, 1 / 2.44 / 3.34E-02
AL512709 / TBC1D16 / TBC1 domain family, member 16 / 2.41 / 3.21E-02
NM_005014 / OMD / osteomodulin / 2.34 / 9.60E-03
NR_024042 / GUCY2E / guanylate cyclase 2E / 2.29 / 2.19E-02
NM_031476 / CRISPLD2 / cysteine-rich secretory protein LCCL domain containing 2 / 2.23 / 4.82E-02
NM_004378 / CRABP1 / cellular retinoic acid binding protein 1 / 2.21 / 3.95E-02
NM_013451 / MYOF / myoferlin / 2.19 / 8.92E-05
NM_203403 / C9orf150 / chromosome 9 open reading frame 150 / 2.16 / 2.10E-02
NM_144665 / SESN3 / sestrin 3 / 2.15 / 4.21E-02
NM_000259 / MYO5A / myosin VA (heavy chain 12, myoxin) / 2.10 / 1.55E-02
NM_020980 / AQP9 / aquaporin 9 / 2.09 / 1.66E-02
NM_015833 / ADARB1 / adenosine deaminase, RNA-specific, B1 / 2.04 / 2.43E-03
NM_018404 / ADAP2 / ArfGAP with dual PH domains 2 / 2.04 / 3.02E-02
NM_001080512 / BICC1 / bicaudal C homolog 1 (Drosophila) / 2.03 / 4.62E-02
NM_017565 / FAM20A / family with sequence similarity 20, member A / 2.02 / 5.04E-03
NM_030817 / APOLD1 / apolipoprotein L domain containing 1 / 2.02 / 3.54E-02
NM_173475 / DCUN1D3 / DCN1, defective in cullin neddylation 1, domain containing 3 (S / 2.02 / 9.61E-03
NM_080491 / GAB2 / GRB2-associated binding protein 2 / 2.00 / 7.89E-03
NM_004952 / EFNA3 / ephrin-A3 / 1.98 / 3.54E-02
NM_005729 / PPIF / peptidylprolyl isomerase F / 1.96 / 2.23E-02
NM_000314 / PTEN / phosphatase and tensin homolog / 1.95 / 2.35E-02
NM_001078171 / FAM127A / family with sequence similarity 127, member A / 1.94 / 1.72E-02
NM_000693 / ALDH1A3 / aldehyde dehydrogenase 1 family, member A3 / 1.90 / 4.66E-02
NM_001099781 / GGT5 / gamma-glutamyltransferase 5 / 1.90 / 3.31E-02
NM_148897 / SDR9C7 / short chain dehydrogenase/reductase family 9C, member 7 / 1.89 / 4.05E-02
NM_198277 / SLC37A2 / solute carrier family 37 (glycerol-3-phosphate transporter), member 2 / 1.87 / 4.02E-02
NM_183239 / GSTO2 / glutathione S-transferase omega 2 / 1.87 / 2.01E-02
NM_001080509 / TSPAN11 / tetraspanin 11 / 1.86 / 2.68E-02
NM_019035 / PCDH18 / protocadherin 18 / 1.85 / 4.76E-02
NM_004969 / IDE / insulin-degrading enzyme / 1.84 / 2.42E-02
NM_003734 / AOC3 / amine oxidase, copper containing 3 / 1.84 / 3.54E-02
NM_001530 / HIF1A / hypoxia inducible factor 1, alpha subunit / 1.82 / 2.20E-02
NM_021570 / BARX1 / BARX homeobox 1 / 1.82 / 3.09E-02
NM_021033 / RAP2A / RAP2A, member of RAS oncogene family / 1.81 / 1.53E-02
NM_033397 / ITPRIP / inositol 1,4,5-triphosphate receptor interacting protein / 1.81 / 2.11E-02
NM_001008707 / EML1 / echinoderm microtubule associated protein like 1 / 1.79 / 4.95E-02
NM_016046 / EXOSC1 / exosome component 1 / 1.77 / 4.38E-02
NM_178169 / RASSF3 / Ras association (RalGDS/AF-6) domain family member 3 / 1.71 / 5.97E-03
NM_020650 / RCN3 / reticulocalbin 3, EF-hand calcium binding domain / 1.70 / 3.62E-02
NM_003952 / RPS6KB2 / ribosomal protein S6 kinase, 70kDa, polypeptide 2 / 1.70 / 5.26E-03
NM_182491 / ZFAND2A / zinc finger, AN1-type domain 2A / 1.69 / 2.46E-02
NM_012124 / CHORDC1 / cysteine and histidine-rich domain (CHORD)-containing 1 / 1.69 / 2.77E-02
NM_017787 / C10orf26 / chromosome 10 open reading frame 26 / 1.67 / 1.21E-02
NM_002663 / PLD2 / phospholipase D2 / 1.67 / 4.23E-02
NR_023356 / MTMR2 / myotubularin related protein 2 / 1.67 / 9.75E-03
NM_001299 / CNN1 / calponin 1, basic, smooth muscle / 1.66 / 4.97E-02
NM_024099 / C11orf48 / chromosome 11 open reading frame 48 / 1.66 / 4.15E-02
NM_024628 / SLC12A8 / solute carrier family 12 (potassium/chloride transporters), member 8 / 1.65 / 4.57E-02
NM_004996 / ABCC1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / 1.65 / 1.80E-02
NM_024756 / MMRN2 / multimerin 2 / 1.64 / 4.59E-02
NM_015507 / EGFL6 / EGF-like-domain, multiple 6 / 1.63 / 2.48E-02
NM_138440 / VASN / vasorin / 1.63 / 3.46E-02
NM_001127205 / HMOX2 / heme oxygenase (decycling) 2 / 1.63 / 4.71E-02
NR_033759 / ATP5L / ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G / 1.63 / 3.51E-02
NM_015221 / DNMBP / dynamin binding protein / 1.63 / 1.85E-02
NM_052875 / VPS26B / vacuolar protein sorting 26 homolog B (S. pombe) / 1.62 / 7.40E-03
NM_002616 / PER1 / period homolog 1 (Drosophila) / 1.62 / 3.42E-02
NM_198794 / MAP4K5 / mitogen-activated protein kinase kinase kinase kinase 5 / 1.61 / 4.00E-03
NM_017907 / C11orf59 / chromosome 11 open reading frame 59 / 1.60 / 4.61E-02
NM_153261 / TMEM188 / transmembrane protein 188 / 1.60 / 1.82E-02
NM_001037343 / CDKL5 / cyclin-dependent kinase-like 5 / 1.60 / 3.01E-02
NM_001025579 / NDEL1 / nudE nuclear distribution gene E homolog (A. nidulans)-like 1 / 1.59 / 1.80E-03
NM_016931 / NOX4 / NADPH oxidase 4 / 1.59 / 4.43E-02
NM_024652 / LRRK1 / leucine-rich repeat kinase 1 / 1.59 / 2.44E-02
NM_014431 / KIAA1274 / KIAA1274 / 1.59 / 4.54E-02
NM_001172509 / SATB2 / SATB homeobox 2 / 1.59 / 4.38E-02
NM_001144058 / NTM / neurotrimin / 1.59 / 3.19E-02
NM_052950 / WDFY2 / WD repeat and FYVE domain containing 2 / 1.59 / 1.05E-02
NM_130464 / NPIPL3 / nuclear pore complex interacting protein-like 3 / 1.58 / 4.29E-02
NM_019087 / ARL15 / ADP-ribosylation factor-like 15 / 1.58 / 4.95E-02
NM_015194 / MYO1D / myosin ID / 1.57 / 3.42E-02
NM_001128159 / VPS53 / vacuolar protein sorting 53 homolog (S. cerevisiae) / 1.56 / 3.64E-02
NM_032587 / CARD6 / caspase recruitment domain family, member 6 / 1.56 / 1.93E-02
NM_001168385 / ALG13 / asparagine-linked glycosylation 13 homolog (S. cerevisiae) / 1.56 / 4.61E-03
NR_027948 / ERC1 / ELKS/RAB6-interacting/CAST family member 1 / 1.55 / 2.20E-02
NM_004691 / ATP6V0D1 / ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 / 1.55 / 4.08E-02
NM_024116 / TAF1D / TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa / 1.55 / 1.58E-02
NM_020698 / TMCC3 / transmembrane and coiled-coil domain family 3 / 1.54 / 2.06E-02
NM_006364 / SEC23A / Sec23 homolog A (S. cerevisiae) / 1.54 / 4.39E-02
NM_001136154 / ERG / v-ets erythroblastosis virus E26 oncogene homolog (avian) / 1.54 / 3.32E-03
NM_001002915 / IGFL2 / IGF-like family member 2 / 1.54 / 3.82E-02
NM_015346 / ZFYVE26 / zinc finger, FYVE domain containing 26 / 1.53 / 1.31E-02
NM_203351 / MAP3K3 / mitogen-activated protein kinase kinase kinase 3 / 1.53 / 1.35E-02
NM_004832 / GSTO1 / glutathione S-transferase omega 1 / 1.53 / 4.76E-02
NM_006195 / PBX3 / pre-B-cell leukemia homeobox 3 / 1.53 / 3.11E-02
NM_033306 / CASP4 / caspase 4, apoptosis-related cysteine peptidase / 1.53 / 1.81E-02
NM_015251 / ATMIN / ATM interactor / 1.53 / 1.89E-02
NM_001142864 / FAM38A / family with sequence similarity 38, member A / 1.52 / 3.77E-02
NM_032322 / RNF135 / ring finger protein 135 / 1.52 / 5.70E-03
NM_001896 / CSNK2A2 / casein kinase 2, alpha prime polypeptide / 1.51 / 3.15E-02
NM_016106 / SCFD1 / sec1 family domain containing 1 / 1.51 / 2.17E-02
NM_032776 / JMJD1C / jumonji domain containing 1C / 1.51 / 2.25E-04
NM_013309 / SLC30A4 / solute carrier family 30 (zinc transporter), member 4 / 1.51 / 3.84E-02
NM_153021 / PLB1 / phospholipase B1 / 1.51 / 2.18E-03
NM_152545 / RASGEF1B / RasGEF domain family, member 1B / 1.51 / 4.90E-02
NR_002775 / RPLP0P2 / ribosomal protein, large, P0 pseudogene 2 / 1.51 / 1.69E-02
NM_004308 / ARHGAP1 / Rho GTPase activating protein 1 / 1.50 / 4.86E-02
NM_181644 / MFSD4 / major facilitator superfamily domain containing 4 / (1.50) / 3.35E-02
NM_003472 / DEK / DEK oncogene / (1.50) / 4.35E-02
NM_016162 / ING4 / inhibitor of growth family, member 4 / (1.51) / 3.40E-02
NM_013328 / PYCR2 / pyrroline-5-carboxylate reductase family, member 2 / (1.51) / 1.74E-03
NM_001168364 / KRTCAP3 / keratinocyte associated protein 3 / (1.51) / 1.96E-02
NM_020935 / USP37 / ubiquitin specific peptidase 37 / (1.52) / 9.38E-03
NM_003526 / HIST1H2BC / histone cluster 1, H2bc / (1.52) / 2.20E-02
NM_175866 / UHMK1 / U2AF homology motif (UHM) kinase 1 / (1.52) / 4.75E-02
NM_152522 / ARL6IP6 / ADP-ribosylation-like factor 6 interacting protein 6 / (1.53) / 2.15E-02
NM_001034194 / EXOSC9 / exosome component 9 / (1.53) / 2.77E-02
NM_001130821 / RABL5 / RAB, member RAS oncogene family-like 5 / (1.53) / 4.09E-02
NM_173083 / LIN9 / lin-9 homolog (C. elegans) / (1.54) / 4.38E-02
NM_033026 / PCLO / piccolo (presynaptic cytomatrix protein) / (1.54) / 6.22E-03
NM_001166417 / SSX2IP / synovial sarcoma, X breakpoint 2 interacting protein / (1.54) / 1.68E-03
NM_004891 / MRPL33 / mitochondrial ribosomal protein L33 / (1.54) / 3.27E-02
NM_018944 / C21orf45 / chromosome 21 open reading frame 45 / (1.55) / 3.38E-02
NM_003495 / HIST1H4I / histone cluster 1, H4i / (1.55) / 1.38E-02
NM_012073 / CCT5 / chaperonin containing TCP1, subunit 5 (epsilon) / (1.56) / 4.08E-02
NM_024102 / WDR77 / WD repeat domain 77 / (1.56) / 8.47E-03
NM_031283 / TCF7L1 / transcription factor 7-like 1 (T-cell specific, HMG-box) / (1.56) / 2.34E-02
NM_152515 / CKAP2L / cytoskeleton associated protein 2-like / (1.57) / 2.91E-02
NM_001618 / PARP1 / poly (ADP-ribose) polymerase 1 / (1.57) / 4.36E-02
NM_012415 / RAD54B / RAD54 homolog B (S. cerevisiae) / (1.58) / 1.60E-02
NM_000898 / MAOB / monoamine oxidase B / (1.58) / 3.09E-02
NM_001229 / CASP9 / caspase 9, apoptosis-related cysteine peptidase / (1.58) / 3.05E-02
NM_018410 / HJURP / Holliday junction recognition protein / (1.58) / 5.16E-03
NM_012343 / NNT / nicotinamide nucleotide transhydrogenase / (1.60) / 4.99E-02
NM_000465 / BARD1 / BRCA1 associated RING domain 1 / (1.60) / 2.46E-02
NM_015143 / METAP1 / methionyl aminopeptidase 1 / (1.60) / 2.81E-02
ENST00000392647 / KLHL23 / kelch-like 23 (Drosophila) / (1.61) / 2.45E-02
NM_001037582 / SCD5 / stearoyl-CoA desaturase 5 / (1.61) / 9.70E-03
NM_006397 / RNASEH2A / ribonuclease H2, subunit A / (1.61) / 1.04E-02
NM_153485 / NUP155 / nucleoporin 155kDa / (1.62) / 3.93E-02
NM_015028 / TNIK / TRAF2 and NCK interacting kinase / (1.62) / 3.66E-02
NM_001185012 / NDUFA2 / NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa / (1.62) / 1.25E-02
NM_003389 / CORO2A / coronin, actin binding protein, 2A / (1.64) / 2.27E-02
NM_017576 / KIF27 / kinesin family member 27 / (1.65) / 6.67E-03
NM_005524 / HES1 / hairy and enhancer of split 1, (Drosophila) / (1.65) / 3.29E-02
NM_002946 / RPA2 / replication protein A2, 32kDa / (1.65) / 1.40E-02
NM_006754 / SYPL1 / synaptophysin-like 1 / (1.66) / 2.42E-02
NM_004168 / SDHA / succinate dehydrogenase complex, subunit A, flavoprotein (Fp) / (1.67) / 3.95E-03
NM_001145316 / DSN1 / DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) / (1.67) / 2.59E-02
NM_004111 / FEN1 / flap structure-specific endonuclease 1 / (1.67) / 2.00E-02
NM_007280 / OIP5 / Opa interacting protein 5 / (1.68) / 3.01E-02
NM_001004309 / ZNF774 / zinc finger protein 774 / (1.68) / 4.59E-02
NM_001130675 / CLGN / calmegin / (1.68) / 2.40E-02
NM_002875 / RAD51 / RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) / (1.68) / 4.71E-03
NM_031422 / CHST9 / carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 / (1.68) / 4.27E-02
NM_138409 / MRAP2 / melanocortin 2 receptor accessory protein 2 / (1.68) / 3.38E-02
NM_000179 / MSH6 / mutS homolog 6 (E. coli) / (1.68) / 9.38E-03
NM_002894 / RBBP8 / retinoblastoma binding protein 8 / (1.69) / 4.80E-02
NM_145697 / NUF2 / NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) / (1.69) / 4.80E-02
NM_006530 / YEATS4 / YEATS domain containing 4 / (1.70) / 1.94E-03
NM_024329 / EFHD2 / EF-hand domain family, member D2 / (1.70) / 4.16E-02
NM_199187 / KRT18 / keratin 18 / (1.71) / 2.53E-02
NM_001130173 / MYB / v-myb myeloblastosis viral oncogene homolog (avian) / (1.71) / 6.05E-03
NM_178865 / SERINC2 / serine incorporator 2 / (1.72) / 3.62E-02
NM_001104629 / C4orf19 / chromosome 4 open reading frame 19 / (1.72) / 1.42E-02
NM_012121 / CDC42EP4 / CDC42 effector protein (Rho GTPase binding) 4 / (1.72) / 3.58E-02
NM_014279 / OLFM1 / olfactomedin 1 / (1.72) / 6.34E-03
NM_002592 / PCNA / proliferating cell nuclear antigen / (1.72) / 1.52E-02
NM_152487 / TMEM56 / transmembrane protein 56 / (1.72) / 1.13E-02
NM_006347 / PPIH / peptidylprolyl isomerase H (cyclophilin H) / (1.72) / 3.13E-02