EXPRESSION OF INTEREST FORM

CLINICAL RESEARCH NETWORK: PRIMARY CARE

PIC - This activity is considered a Patient Identification Centre study

STUDY TITLE:
Linear and non-linear brain changes over the transition to Psychosis: The BrIT study (Brains in Transition) / (ACRONYM)
BrIT / INSERT STUDY LOGO

NIHR PORTFOLIO REF: 15937 / NHS ETHICS REF: 13/WM/0399
CHIEF INVESTIGATOR: Prof Stephen Wood / FUNDER:MRC / SPONSOR: University of Birmingham
MAIN STUDY OBJECTIVE PRACTICE INVOLVEMENT
  • To better understand the brain changes that occur during the transition from the 1. Conduct a search to identify potentially eligible patients
at-risk mental state to the development of a psychotic episode. 2. GP to check patient list
  • To establish to what extent these changes in brain patterns and clinical presentation 3. Conduct a mail-shot inviting potentially eligible patientsto
can be used to improve early detection of individuals at greatest risk find out more about the study .
Overall the study could lead to better targeting of therapeutic interventions aimed at 4.Permission to display study poster
preventing, or at least ameliorating, the onset of psychotic disorders such as schizophrenia

INCLUSIONCRITERIA PARTICIPANTS INVOLVEMENT
  • Willingness and eligibility to have MRI scans At least 2 visits in a year to the University of Birmingham
  • Aged 16-35 2-4 hour assessments including clinical interview and MRI scan
  • Help seeking The participantwill receive £20 each time for taking part
  • Suspected to be at risk for psychosis(i.e. experiencing low level, sub-threshold psychotic
symptoms or has first degree relative with a psychotic illness)
REIMBURSEMENT
EXCLUSION CRITERIA An estimated NHS Service support cost payment of £225.26
  • Individuals unable to provide informed consent/lack English capacity to complete assessment has been calculated for this study. This figure is based upon
  • Presence of a neurological disorder such as epilepsy; history of head injury involving loss the information provided by the study team regarding the likely
of consciousness over 5 minutes or overnight hospital stay, claustrophobia and activities to be performed by your Practice; it is an approximation
contraindications for MRI such as a pacemaker. only and may be adjusted in line with the amount of patient
Please note this will be checked by the research team before obtaining consent recruitment and the level of CRN support received
RECRUITMENT PERIOD: Open until 31 January 2017 / TRIAL POPULATION: 144
LOCAL CO-ORDINATOR/FACILITATOR:Anu Krishna / TEL: 0121 4146643 / EMAIL:
ADDRESS: Clinical Research Network: Primary Care, Primary Care Clinical Sciences, Learning Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT

FAX REPLY: 0121 414 6571

YES PLEASE I would be interested in finding out more about this study. / NO THANKYOU, I am not interested at this time.
It would be helpful to the study team if you could indicate below why your practice would not wish to be involved at this time:

Too busy Funding Study not suitable
Practice not interested in research Other
PRACTICE CODE: Populate from database
PRACTICE NAME: Populate from database
PRACTICE ADDRESS: Populate from database
PRACTICE CONTACT:
ROLE:
Tel: Email: