Supplementary Bachelor of Physiotherapy I (First) Year Annual Examination 2013-14

Course Code: BPT104 Paper ID: S111133

Biochemistry

Time: 3 Hours Max. Marks: 70 Max Marks: 75

Note: Attempt the questions as per instructions Q. No. 1 is compulsory.

1. Choose the correct alternative: (1x10=10)

i) Oxidation of which substance in the body yields the most calories:

a) Glucose b) Glycogen

c) Protein d) Lipids

ii) Genetic information of nuclear DNA is transmitted to the site of protein synthesis by:

a) rRNA b) mRNA

c) tRNA d) Polysomes

iii) The milk protein in the stomach of the infants is digested by:

a) Pepsin

b) Trypsin

c) Chymotrypsin

d) Rennin

iv) In adults a severe deficiency of vitamin D causes:

a) Night blindness

b) Osteomalacia

c) Rickets

d) Skin cancer

v) Correct ordering of lipoprotein molecules from lowest to the greater density is:

a) LDL, IDL, VLDL, chylomicron

b) Chylomicron, VLDL, IDL, LDL

c) VLDL, IDL, LDL, chylomicron

d) LDL, VLDL, IDL, chylomicron

vi) The enzyme that converts glucose to glucose-6-phosphate is:

a) Phosphatase

b) Hexokinase

c) Phosphorylase

d) Glucose synthetase

vii) The number of ATP produced in the oxidation of 1 molecule of NADPH in oxidative phosphorylation is:

a) Zero b) 2

c) 3 d) 4

viii) ACTH stimulates the secretion of:

a) Glucocorticoids

b) Epinephrine

c) Thyroxine

d) Luteinizing hormone

ix) DNA does not contain:

a) Thymine

b) Adenine

c) Uracil

d) Deoxyribose

x) Urea synthesis takes place in:

a) Blood b) Liver

c) Kidney d) Heart

2. Answer any six of the following (limit your answer to 50 words). (6x5=30)

a) Glycolysis and its biomedical importance.

b) Classification of Enzymes.

c) Role of Vitamin D and Parathormone in osteoporosis

d) Differentiate between DNA & RNA.

e) Balanced Diet.

f) Hyperlipidemia and its causes

g) Role of insulin and glucagon in carbohydrate metabolism

h) Differentiate between diabetes mellitus and diabetes insipidus.

i) Lipid profile test and significance of each parameters.

3. Attempt any two of the following.

a) How bilirubin is formed? Breifly explain significance of liver function test in pre hepatic, hepatic and post hepatic jaundice. (15)

b) Explain in details about biochemistry of muscles contraction with well labelled diagram. (15)

c) Why TCA cycle is amphibolic in nature? Explain in details about TCA cycle and its bioenergetics. (15)

(12)

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