1221 Poster Cat: Primary Prevention of Cardiovascular Disease: Assessment and Management of Risk 21. Factors, Lifestyle Changes
RELATION BETWEEN SECONDHAND SMOKE EXPOSURE AND CARDIOVASCULAR RISK FACTORS IN NEVER SMOKERS
T.J. Youn1, S.H. Kang1, D.G. Park2, K.J. Ahn3
1. College of Medicine, Seoul National University and Seoul National University Bundang Hospital, Seongnam, Korea
2. Hallym University Kangdong Sacred Heart Hospital, Seoul, Korea
3. Hanil General Hospital, Seoul, Korea
Objective: Secondhand smoke exposure (SHSE) in non-smokers has been associated with premature cardiovascular mortality and ischemic heart disease. We conducted a cross-sectional, population-based study evaluating the relationship between SHSE, measured by subjective and objective methods, and conventional cardiovascular risks such as blood pressure and lipid profiles.
Methods: We extracted information on 7,376 healthy adults who had never smoked, for whom there were available urine cotinine levels, from the Korea National Health and Nutrition Examination Survey 2008–2011. SHSE was defined using self-report questionnaires and urine cotinine levels. The main outcomes included systolic and diastolic blood pressure and serum lipid profiles.
Results: The mean age of the study population was 45.4 years and 77.8% were female. Self-reported SHSE had no significant association with study outcomes except for diastolic blood pressure and serum triglyceride levels, which had marginally positive relationships (p=0.078 and 0.070, respectively). Unadjusted models found no significant relationship between urine cotinine levels and any study outcomes. Triglyceride level was inversely associated with urine cotinine after multivariable adjustment (p=0.015); there were no significant relationships between other outcomes.
Conclusions: Although SHSE is associated with increased risk of cardiovascular mortality and morbidity, we did not find any significant relationship between SHSE and blood pressure or lipid levels in this cross-sectional study. Using objective measurements of urine cotinine did not alter this relationship. Further long-term prospective studies are needed to evaluate the effect of SHSE as a cardiovascular risk factor.