Curriculum Vitae
John Michael Pezzuto
Biographical Sketch: Dr. Pezzuto received his A.B. degree in chemistry from Rutgers University (1973) and Ph.D. in biochemistry from the University of Medicine and Dentistry of New Jersey (1977). He then performed two years of postdoctoral work in the Department of Chemistry at Massachusetts Institute of Technology, where he was the recipient of a postdoctoral fellowship from the National Cancer Institute. Following a one-year stay at the University of Virginia, as Instructor of Chemistry, he accepted a faculty position (Assistant Professor) at the University of Illinois at Chicago (1980). He was promoted to the rank of Associate Professor in 1984, and to full professor in both the College of Pharmacy (1991-2002) and the College of Medicine (1994-2002) at the University of Illinois at Chicago. He was named Distinguished University Professor in 2002. He served as Head (1993-1995) and Interim Head (2000-2001) of the Department of Medicinal Chemistry and Pharmacognosy at the UIC College of Pharmacy, Associate Director of the UIC Cancer Center (1991-1995), and Director of the Program for Collaborative Research in the Pharmaceutical Sciences (1995-1998), the leading research unit affiliated with the UIC College of Pharmacy. He later served as Associate Dean for Research and Graduate Education, UIC College of Pharmacy (1998-2002), Deputy Director of the UIC Cancer Center (2000-2002), and Head of the Department of Medicinal Chemistry and Pharmacognosy (2001-2002). In 2002, Dr. Pezzuto accepted the position of Professor of Medicinal Chemistry and Molecular Pharmacology, and Dean of the College of Pharmacy, Nursing and Health Sciences, at Purdue University, West Lafayette, Indiana (2002-2006). He also served as Chief Scientific Officer for pharmaceutical development at McClure Park, Inc., an affiliate of the Purdue Research Foundation (2004-2006). In 2006, Dr. Pezzuto became the Founding Dean of the Daniel K. Inouye College of Pharmacy at the University of Hawaii at Hilo. Over the period of nine years, the College was built from the ground up, now holding a respectable position in academic pharmacy. He is currently Professor and Dean of the Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, and holds adjunct professorial positions at the University of Illinois at Chicago, Purdue University, and the University of Hawaii. He is an author of over 500 publications, co-inventor of several patents, the editor of four books, member of over 10 editorial boards of international journals, the former editor-in-chief of the International Journal of Pharmacognosy (1990-1995), the former editor-in-chief of Combinatorial Chemistry and High Throughput Screening (1996-1997), and the current editor-in-chief of Pharmaceutical Biology. He served as a full member of Subcommittee E (cancer epidemiology, prevention and control) of the National Cancer Institute (2003-2007). He was the recipient of a Research Career Development Award from the National Cancer Institute (1984-1989) and a Research Fellowship from the Alexander von Humboldt Foundation (1990-1991). During the period of the Humboldt fellowship, he held a research position in the Department of Pharmaceutical Biology at the University of Munich. He has directed the research of numerous doctoral students, postdoctoral associates, and visiting scholars. He was elected Senior University Scholar at UIC in 1999, UIC Inventor of the Year in 2000, Fellow of the American Association for the Advancement of Science in 2012, and recipient of the Volwiler Research Award by the American Association of Colleges of Pharmacy in 2014. His current research interests are predominately in the areas of biology-driven natural product drug discovery and characterization, with primary emphasis in the fields of cancer chemotherapy and cancer chemoprevention. He received financial support by the National Institutes of Health for over 35 years, and currently directs a long-term project designed to investigate the effect of grape consumption on health and longevity. He resides in Brookville, NY, with his wife and three children.
Contents
Curriculum Vitae 1
Personal Data 1
Academic/Professional Positions 1
Education 4
Awards and Honors 4
Research Interests 6
Teaching Experience (examples) 7
Administrative Responsibilities/Experience 8
Committees (examples) 10
Theses Committees 12
Grant and Manuscript Reviews (partial listing) 13
Miscellaneous External Reviews 20
Editorial Positions 21
Listing in Reference Sources 22
Patents/Disclosures 22
Licensing Agreements 24
Drug Development Applications 24
Consulting/Advisory Groups 24
Examples of Public Service/Relations/Communications 26
Purdue University College of Pharmacy, Nursing, and Health Sciences Activities 30
School activities: 30
School publications: 30
University memberships: 30
Other memberships: 31
Teaching: 31
University of Hawaii at Hilo, College of Pharmacy Activities 31
Supervision of Research Personnel 32
Extramural Funding 35
Funded (Previous) 35
Funded (Currently Active at LIU) 40
Funding (Submitted/in Preparation) 40
Master Agreements 41
Gifts Provided to Support Research Initiatives 41
Intramural Funding 41
Publications 42
Ph.D. Dissertation 42
Articles in print/in press 42
Articles Submitted/Actively In Preparation 82
Book Chapters 83
Book Reviews 87
Miscellaneous Editorial Contributions 88
Books/Proceedings Edited 89
Published Abstracts and Papers Presented 89
Meetings or Symposia Chaired/Organized; Workshops Conducted 138
Complete Works Reprinted or Abstracted in Secondary Sources 140
ii
Personal Data
Name: John Michael Pezzuto
Home Address: 22 Norgate Road
Brookville, NY 11548
Mailing Address: Arnold & Marie Schwartz College of Pharmacy and Health Sciences
Long Island University
75 DeKalb Ave.
Brooklyn, NY 11201
Communications: (808) 960-1698 (Cell)
(718) 488-1004 (Business)
(718) 488-0628 (Fax)
(E-mail)
Birth: August 29, 1950 [to Michael L. Pezzuto and Elizabeth Brown (Pezzuto)]
Place of Birth: Hammonton, New Jersey
Nationality: U.S. Citizen
Family Status: Married [Mimi Faith Rotstein (Pezzuto), R.Ph.], three children (John-Henry Albert, born 5 September 1993; Elisabeth Lee, born 23 August 2000; Michael Joseph Ivan, born 14 January 2002).
Academic/Professional Positions
1973-1977 Teaching Assistant, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey
1977-1979 Postdoctoral Associate, Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts (NIH Postdoctoral Trainee, 1977-1978; NIH Postdoctoral Fellow, 1978-1979)
1979-1980 Instructor of Chemistry, Department of Chemistry, University of Virginia, Charlottesville, Virginia (NIH Postdoctoral Fellow)
1980-1983 Assistant Professor, Department of Pharmacognosy and Pharmacology, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois (the department was re-organized in 1983)
1981-2002 Member, Graduate College, University of Illinois at Chicago, Chicago, Illinois
1983-2002 Member, Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1983-1984 Assistant Professor, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1984-1989 National Institutes of Health Research Career Development Awardee
1984-1991 Associate Professor, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1985-1992 Associate Professor, Department of Surgery, Division of Surgical Oncology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
1987-1991 Member, Specialized Center for Cancer Research and Education, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
1989-1991 Attending Member, Scientific Staff, Department of Surgery, Michael Reese Hospital and Medical Center, Chicago, Illinois
1990-1991 Research Fellow, Alexander von Humboldt Foundation, Federal Republic of Germany
1990-1991 Visiting Scientist, Institute for Pharmaceutical Biology, University of Munich, Munich, Federal Republic of Germany
1991-1994 Program Leader, Pharmacology and Developmental Therapeutics, Specialized Cancer Center, University of Illinois at Chicago, Chicago, Illinois
1991-2002 Professor, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1991-2002 Director, Bioassay Research Facility, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1991-1995 Associate Director, Specialized Cancer Center, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
1991-1996 Editor-in-Chief, International Journal of Pharmacognosy, Swets & Zeitlinger Publishers.
1992-1995 Interim Head, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1992-1995 Director, Graduate Program in Medicinal Chemistry, University of Illinois at Chicago, Chicago, Illinois
1992-2002 Professor, Department of Surgical Oncology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois
1995-1998 Director, Program for Collaborative Research in the Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois
1996-1997 Director (pro tempore), Center for Pharmaceutical Biotechnology, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
1996-1998 Associate Editor, International Journal of Pharmacognosy, Swets & Zeitlinger Publishers.
1996-1997 Editor-in-Chief, Combinatorial Chemistry and High Throughput Screening, Bentham Science Publishers.
1996-2002 Program Leader, Cancer Chemoprevention, University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois
1997-present Editor-in-Chief, Pharmaceutical Biology, Informa Healthcare, publishers.
1998-2002 Associate Dean for Research and Graduate Education, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
2002 Deputy Director, University of Illinois Cancer Center, Chicago, Illinois.
2000-2001 Interim Head, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
2002 Head, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
2002 Distinguished University Professor, University of Illinois at Chicago, Chicago, Illinois
2002-present Adjunct Professor, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois
2002-2006 Professor, Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue University, West Lafayette, Indiana
2002-2006 Dean, College of Pharmacy, Nursing and Health Sciences, Purdue University, West Lafayette, Indiana
2004-2006 Chief Scientific Officer for Pharmaceutical Development, McClure Park Inc., West Lafayette, Indiana
2006-present Adjunct Professor, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana
2006-2009 Professor, Department of Chemistry, College of Liberal Arts and Science, University of Hawaii at Hilo, Hilo, Hawaii
2009-2015 Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Hawaii at Hilo, Hilo, Hawaii
2006-2015 Professor and Founding Dean, Daniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo Hawaii (designated Dean Emeritus)
2010-2015 Adjunct Professor, Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa
2015-present Professor and Dean, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY
Education
1973 Rutgers University, Camden, N.J.
Degree of Bachelor of Arts majoring in chemistry. Minor in mathematics; some supplementary work was done concerning theoretical wave equations.
1977 University of Medicine and Dentistry of New Jersey - New Jersey Medical School, Newark, N.J. (now Rutgers University)
Degree of Doctor of Philosophy. Graduate Student Association (departmental representative); several committee positions; Teaching Assistantship.
Awards and Honors
Over the years, I have presented keynote addresses at prominent institutions throughout US, other parts of North American, South America, Asia, and Europe. My work on resveratrol has been cited over 3,000-times and has inspired approximately 15,000 papers in the field. My h-index is over 60. In addition to basic research, however, I have strongly advocated for the profession of pharmacy. I have presented keynote addresses at venues such as the APhA, Hawaii Pharmacists Association, Rho Chi inductions, White Coat ceremonies, and many more. I have supported and fostered the development of clinical pharmacy programs in Indianapolis while at Purdue and neighbor islands including Oahu while at UH Hilo. I have supported preceptors, residents, and innovative approaches for pharmacy education. I have served on the Hilo Medical Center Foundation and I have been recognized by the community for contributing to improvements in health care. At Hawaii, a $14 M award was received from CMS to promote the role of the pharmacist in healthcare transitions from hospitals to the community. A $16 M dollar award was received to create a Beacon Community. Some honors and awards are listed below.
NIH Postdoctoral Trainee and Fellow, 1977-1980.
NIH Research Career Development Awardee, 1984-1989.
Research Fellow, Alexander von Humboldt Foundation, 1990-1991.
Presented lecture entitled “Discovery of Betulinic Acid as a Selective Inhibitor of Human Melanoma that Functions by Induction of Apoptosis” at the first "Late-breaking Research Session" of the 86th Annual Meeting of the American Association for Cancer Research, Toronto, Canada, March 1995.
Presented keynote lecture entitled “Natural Product Chemopreventive Agents” at the 2nd International Congress on Phytomedicine and 7th Congress of the German Society of Phytotherapy, Munich, Germany, September 1996.
Editor-in-Chief, Pharmaceutical Biology, 1997-present.
Presented keynote lecture entitled “Natural Products: The Backbone of Novel Drug Discovery” at the 24th Annual MALTO meeting, University of Arkansas, Little Rock, Arkansas, May 1997 (invited participant in a special symposium entitled "Frontiers in Pharmaceutical Research and Their Impact on Graduate Education").
Presented lecture entitled “Discovery and Characterization of Natural Product Cancer Chemopreventive and Chemotherapeutic Agents” at the 3rd Cycle in Pharmaceutical Sciences, Search for New Lead Compounds and in Particular Anticancer and Antiviral Agents of Natural Origin, Zermatt, Switzerland, October 1997.
Presented lecture entitled “Breakthroughs in Natural Product Drug Discovery at UIC” at the UIC Corporate and Foundation Donor Recognition Luncheon, Chicago, IL, March 1998.
Presented inaugural address entitled “Bioassay-Driven Natural Product Drug Discovery,” Department of Biology, Yildiz Technical University, Istanbul, Turkey, May 1998.
Presented inaugural address entitled “Development of Bioassay Systems Necessary for the Discovery of Natural Product Drugs,” Research and Development Centre for Applied Chemistry, Indonesian Institute of Sciences, Bandung, Indonesia, June 1998.
Elected Senior University Scholar, University of Illinois at Chicago, 1999.
Presented the Varian Lectures in Chemistry and Biology, entitled "Natural Inhibitors of Carcinogenesis" and "In Vitro Models of Human Disease States," University of Ottawa Department of Chemistry, February 2000.
Presented keynote address entitled "Cancer Chemoprevention, Great Hope for the New Millenium" at the XXI Research Forum of the Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico, April 2000.
Elected University of Illinois at Chicago Inventor of the Year, 2000.
Listed in ISIHighlyCited.com (Current Contents) as one of the most highly cited publishing researchers (includes less than 0.5% of researchers), 2002.
Appointed Distinguished University Professor, University of Illinois at Chicago, 2002.
Received Distinguished Alumnus Award, University of Medicine & Dentistry of New Jersey, May 2003.