ESM Table 2. Baseline characteristics of the study population in the Finnish Diabetes Prevention Study divided according to the genotypes of rs1342387 of the ADIPOR1gene
rs1342387 /A/A
/ A/G / G/G / p / pSex (male/female) / 32/84 / 71/153 / 56/83 / 0.124g
Age (years) / 56.3±7.0 / 55.1±6.9 / 55.6±7.1 / 0.420a
Weight (cm) / All
Male
Female / 84.1±13.6 (126)
91.3±12.8 (35)
81.3±12.9 (91) / 85.1±13.3 (232)
89.5±11.8 (73)
83.1±13.5 (159) / 89.7 ±15.4 (149)
93.5±13.7 (58)
87.2±16.1 (91) / 0.008c
0.134b
0.040b
Height (cm) / All
Male
Female / 164.0±8.5 (126)
173.8±6.5 (35)
160.3±5.8 (91) / 166.1±8.6 (232)
175.0±6.6 (73)
162.0±5.9 (159) / 167.8±8.2 (149)
175.0±5.7 (58)
163.1±5.9 (91) / <0.001a
0.537b
0.009b / 0.314e
0.070e
BMI (kg/m2) / All
Male
Female / 31.2±4.3 (126)
30.2±3.5 (35)
31.6±4.5 (91) / 30.9±4.4 (232)
29.2±3.1 (73)
31.7±4.7 (159) / 31.8±4.9 (149)
30.5±3.9 (58)
32.7±5.4 (91) / 0.144a
0.074b
0.289b
Waist circumference
(cm) / All
Male
Female / 100.8±11.0 (125)
105.0±9.8 (35)
99.2±11.1 (90) / 100.1±10.3 (232)
102.2±9.1 (73)
99.1±10.6 (159) / 103.4±11.8 (148)
105.6±10.3 (58)
102.0±12.5 (90) / 0.034c
0.114b
0.181b / 0.660f
0.956d
0.749d
Hip circumference
(cm) / All
Male
Female / 109.5±9.0 (126)
105.7±6.8 (35)
111.0±9.3 (91) / 109.3±9.7 (232)
104.0±6.6 (73)
111.8±9.9 (159) / 111.7±11.6 (149)
106.6±8.6 (58)
115.0±12.1 (91) / 0.223a
0.229a
0.048a
Waist-to-hip ratio (cm) / All
Male
Female / 92.14±7.37 (125)
0.99±0.05 (35)
0.89±0.06 (90) / 91.72±7.20 (232)
0.98±0.05 (73)
0.89±0.06 (159) / 92.67±7.57 (148)
0.99±0.05 (58)
0.89±0.06 (90) / 0.408c
0.522b
0.536b / 0.373f
0.890d
0.437d
Sagittal diameter (cm) / All
Male
Female / 24.6±2.9 (125)
24.9±3.4 (35)
24.5±2.8 (90) / 24.6±3.1 (230)
24.5±3.1 (72)
24.6±3.1 (158) / 25.5±3.3 (149)
25.3±3.0 (58)
25.6±3.5 (91) / 0.008c
0.289b
0.028b / 0.130f
0.663d
0.083d
Horizontal diameter (cm) / All
Male
Female / 38.1±3.7 (125)
36.1±3.3 (35)
38.9±3.6 (90) / 38.1±4.0 (230)
35.8±3.1 (72)
39.2±4.0 (158) / 39.3±4.5 (149)
37.3±2.9 (58)
40.5±4.9 (91) / 0.001c
0.016b
0.032b / 0.010f
0.063d
0.110d
Fasting plasma glucose (mmol/l) / All
Men Women / 6.1±0.8 (126)
6.3±0.9 (35)
6.0±0.8 (91) / 6.1±0.7 (232)
6.3±0.8 (73)
6.0±0.7 (159) / 6.2±0.7 (149)
6.1±0.7 (58)
6.2±0.7 (91) / 0.771c
0.185a
0.291a / 0.078f
2-h plasma glucose (mmol/l) / All
Men Women / 8.7±1.5 (126)
8.3±1.7 (35)
8.8±1.4 (91) / 8.9±1.5 (232)
8.9±1.6 (73)
9.0±1.5 (159) / 9.0±1.4 (149)
8.9±1.5 (58)
9.0±1.4 (91) / 0.165a
0.113a
0.529a
Fasting serum insulin (mU/l) / All
Men Women / 14.1±7.8 (119)
15.9±9.2 (32)
13.4±7.1 (87) / 14.5±7.0 (209)
16.1±8.7 (62)
13.9±6.0 (147) / 15.8±7.7 (133)
15.1±7.7 (142)
16.2±7.7 (85) / 0.090a
0.748b
0.024b / 0.069d
0.066d
2-h serum insulin (mU/l) / All
Men Women / 91.7±76.5 (119)
77.2±41.0 (32)
97.0±85.5 (87) / 93.8±61.0 (206)
97.3±64.0 (62)
92.3±60.0 (144) / 100.5±60.1 (133)
99.6±69.0 (48)
100.9±54.9 (85) / 0.197c
0.365b
0.251b / 0.203f
0.209d
0.455d
Data are means±SD (n). aKruskal–Wallis test; bANOVA for comparison among all three genotype groups, adjusted for age; cANOVA for comparison among all three genotype groups, adjusted for age and sex; dANOVA for comparison among all three genotype groups, adjusted for age and BMI; eANOVA for comparison among all three genotype groups, adjusted for age and weight; fANOVA for comparison among all three genotype groups, adjusted for age, sex and BMI; gc2 test.