Medicine Third Long Exam 2009-2010

1)  Dermographism is usually associated with:

a.  Bullae

b.  Nebule

c.  Wheal

d.  Macule

2)  Pigmented macules of Peutz-Jeghers Syndrome are always present on:

a.  External nares

b.  Lips and oral mucous membranes

c.  Fingers

d.  Axillary folds

3)  Ash, leaf-shaped hypopigmented macules on arms, legs, and trunk are seen in:

·  Tuberous sclerosis

4)  A person who scratches a pruritic lesion may develop:

a.  Excoriations

b.  Lichenification

c.  Crusts

d.  Any of the above

5)  Which of the following is of utmost importance in the history of a patient diagnosed with allergic contact dermatitis?

a.  Drug ingestion

b.  Travel history

c.  Hobbies or occupation

d.  Sexual history

6)  Forty-three year old saleslady complains of an ulcer on the right medial malleolus of five months’ duration. When you inspected her legs, it revealed varicosities. What is your diagnosis of the ulcer?

·  Venous

7)  Heliothrope rash is seen in:

·  Dermatomyositis

8)  A seven year old with fish-like scales on both shins of two years’ duration will have most likely which of the following?

a.  Lichen simplex chronicus

b.  Lichen planus

c.  Allergic contact dermatitis

d.  Atopic dermatitis

9)  A 55-year old male scratches the dorsum of his foot with a comb whenever it itches. After a few months, which of the following lesions will most likely be seen?

a.  Lichenification

b.  Scar

c.  Wheal

d.  Nodule

10)  In a lesion of a person with a family history of atopy, the major criteria for acute dermatitis is:

a.  Typical morphology or distribution

b.  Pruritis

c.  Chronicity

d.  All of the above

11)  Pellagra appears to be caused by a deficiency of:

·  Nicotinic acid (Vitamin B3)

12)  A nineteen-year-old nursing student consults for recurrent deep-seated tapioca-like pruritic vesicles on the sides of her fingers affecting both hands. What will you prescribe as treatment?

·  Clobetasone cream

13) Steroids are discouraged in the treatment of

a. (audio was unclear…sorry) dermatitis (based from our lecture, steroids should be avoided in the treatment of asteatotic eczema)

14) Pretibial myxedema is associated with

a. adrenal problem

b. hyperlipidemia

c. thyroid dysfunction

d. diabetes

15) Gardner’s syndrome presents with:

a. Polyposis coli

b. epidermatitis

c. skeletal abnormalities

d. all of the above

16) A positive ostrich sign is a pathopneumonic for which of the following scaling disorder?

a. Keriatis (audio was unclear…sorry) vulgaris

17) Herald patch is the usual lesion seen in:

b. Pityriasis rosea

18) Pemphigus vulgaris, an autoimmune blistering disease presents with flaccid bullae which easily ruptures on the level of split of which layer?

a. Subepidermal

b. Intradermal

c. Subterial

d. Subcutaneous

19) 35 year old female with Stevens Johnson syndrome secondary to anticonvulsants, what type of lesion do you look for?

c. Target lesion

20) 65 year old male who has an ulcer on the medial malleolar area: the diagnosis is

a. Arterial

b. Neurotropic

c. Venous

d. Decudeter

21) A scar which spreads beyond the initial injury is

b. keloid

22) Sand? allopecia may be one of the dermatologic presentation of

a. SLE

b. Syphilis

c. Both

d. Neither

23) Alopecia in SLE is caused by

C. an autoimmune damage to the hair follicle

24) A 35 year old male with multiple patches and fine scaling at the periphery on?? the trunk. The diagnosis is Pityriasis Rosea. PE revealed similar lesions on the palms and soles. You now suspect that the patient has:

a. Scabies

b. Folliculitis

c. Secondary Syphilis

d. Psoriasis

25.) Diagnosis for syphillis? C. VDRL

26.) The lesion/ cutaneous manifestation for lichen planus? D. Wickham’s striae

27.) Neurofibromatosis will present: A. Café au lait spots

28.) In meningococcemia, lesions are actually: E. Septic emboli

29.) Basal cell carcinoma presents with C. Diabetic ulcer

30.) Polycystic ovarian syndrome presents with B. Hirsutism

31.) 30-year old female, asthmatic, complains fish-like scales on the shin. Diagnosis? A. Ichthyriosis

32.) A common deformity of the wrist seen in patients with Rheumatoid Arthristis

a. ulnar deviation c. median deviation

b radial deviation d.Swan-like deformity

33.) Muscles form the rotator cuff except:

a.Infraspinatus c. Teres Minor

b. Suprapinatus d. Teres Major

34.) Full abduction of the shoulder has two components, one of which is:

a. movement of clavicle and scapula in relation to the thorax

b. movement includes extension and supination of the forearm

c. movement includes flexion and pronation of the forearm

d, rotation of the arm externally

35.) These are functions of talo-calcaneal and transverse tarsal joints:

a. dorsiflexion and plantar flexion

b. adduction and abduction of the ankle joint

c. medial and lateral deviation of the feet

d. inversion and eversion of the feet

36.) Which of the following does not form the knee joint?

a. fibula c. femur

b. tibia d. patella

37) When the patient is lying down, raise the leg…. (did not understand, sorry)…move laterally, what will happen?

a. the… (did not understand, sorry)… is abducted

b. the hips remain in their position

c. the hip is abducted

d. the femur rotates internally

38) In examining the patient from the side, one of these will be abnormal:

a. cervical convexity

b. thoracic concavity

c. lumbar concavity

d. sacral convexity

39) Which of the following statements is INCORRECT?

a. the most mobile portion of the spine is the neck

b. lateral bending involves the cervical spine from the second to the seventh vertebra

c. flexion and extension occurs freely between the head and the fourth cervical

d. rotation occurs primarily between the second and third vertebra

40) Asking the patient questions like if he/she has difficulty with walking, climbing stairs, getting up from bed is very important in assessing:

a. pain

b. functional status

c. inflammation

d. decreased activity

41) The focused and systematic 5-minute musculoskeletal exam is known as:

a. GIRLS

b. GOALS

c. GALS

d. GODS

42) Gait is assessed by the following EXCEPT:

a. free movement of shoulders

b….(did not understand, sorry)… and symmetry of the legs

c. spine curvature

d. shoulder and arm movement

43) Schouder’s test is said to be normal when:

a. the distance between two points is increased by at least 5 centimeters

44) (did not understand, sorry)… motion of the thumb and index finger is test for what?

c. fine precision grip

45) To determine the functional status of the hand, you may perform the following EXCEPT:

a. ask the patient to make a fist

b. do a power grip

c. do fine precision grip

d. squeeze the hand at the area of metacarpophalangeal joint

46) As you observe the patient while he walks, you noticed that he has a tilt to one side. This gait is called:

a. Gala gait

b. Arthralgic gait

c. Anthalgic gait

d. Arthritic gait

47) What is called the patients calling card?

a. head

b. (did not understand, sorry)…

c. hands

d. face

48) Which is not seen when examining the spine from behind?

a. spinal curvature

49.  Asking the patient to put his hands at the back of his neck, it detects if the patient is (……)

ANS. B)Shoulders

50.  All of the following are signs of general inflammation except.

ANS. D) Crepitation

51.  The presence of this in the (….) is called what sign?

ANS. A. Bulb sign

52.  Sings of osteoarthritis in the knee except

ANS. (Valvus??)

53.  Which of the following lacks a bigger (….)

ANS. A) Thumb

54.  Hyper (extension???) of the proximal IP (….) deflection at the distal IP (….) is known as what deformity?

ANS. B) Swan neck deformity

55.  (….) of the cervical spine, you ask the patient to do what?

ANS. C) Chin to shoulder

56.  Movement of the (elbow joints??) are all of the following except

ANS. A) Rotation

57.  (computation for ANION GAP)

ANS. 18

58.  A lobar(….) concentration may be seen in (….) simple acid base disorder

ANS. B) Metabolic acidosis and Respiratory Alkalosis

59.  (Seizures??) of confrontation for primary acid base disturbance

ANS. B) Confrontation is not complete

61) The normal ratio of bicarbonate to CO2 is:

a. 1:1 c. 10:1

b. 2:1 d. 20:1

62) Pneumonia most likely results to which acid-base derangement?

a. metabolic acidosis c. respiratory acidosis

b. metabolic alkalosis d. respiratory alkalosis

63) What is the pCO2 if the plasma CO2 concentration is 1.144 mmol?

a. 38

64) What is the unit in mmHg to which pCO2 will fall in response to metabolic acidosis?

a. 4-6 c.12-14

b.16-18 d.8-10

65) Which of the following is a normal anion gap result?

a. 11 c.16

b. 18 d. 8

66) A cause of high anion gap acidosis is:

c. End stage renal disease

67) An effect of metabolic acidosis:

a. central venodilatation c. decreased myocardial contractility

b. peripheral vasoconstriction d. decreased tissue unloading

68) Metabolic alkalosis develops in..

a. hypokalemia

69) Hyperalbuminemia, low protein leads to (?)

a. increased anion gap

b. decreased anion gap

70) Which of the following results to a primary respiratory alkalosis?

b. hypoxemia

71) Supportive management of respiratory acidosis include:

a. c. bicarbonate infusion

b. rapid correction of hypercapnea d. severity of disorder influences management

72) pCO2 results of 34 mmHg may be seen in patients with:

a. metabolic acidosis c. acute respiratory acidosis

b. metabolic alkalosis d. chronic respiratory acidosis

73.) pH=7.38 pCO2=32 HCO3=18.4 Anion gap=14

b. Metabolic Acidosis

74.) ……….

a. ………..

75.) ……….

d. Respiratory Acidosis

76.) ………..

c. Metabolic Alkalosis

77.) A 40 y.o. male ….. fever, on and off cough ….. P. E revealed decreased fremitus and dullness to percussion ……

d. Pleural Effusion

78.) Patient complained of cough and dyspnea …..

b. Atelectasis

79.) …... prolonged expiratory time …..

b. …..

80.) ….. paralyzed hemidiaphragm….., deep expiration …..

b. as it moves upward into the thoracic cavity

81.) Stridor is present in what condition?

c. Laryngeal edema

82.) Which of the following is true of sound ….. by the normal lung?

a. whispered words are unintelligibly heard on auscultation

83.) Which of the following will characterize rhonchi?

c. they change in character after a strong productive cough

84.) ……….

d. prevent premature ….. of the distal airway

85. Kussmauls breathing most likely entails that patients have Metabolic acidosis

86. Where is tympany normally appreciated on the chest wall? Over the left lower anterior chest while the patient is supine

87. 51yr old female has cough 3 weeks, worries that her father has been diagnosed with lung CA a month ago and fears she might also develop the same disease Psychogenic cough

88. 27 male, reproductive cough over 3 weeks, TB suspected… Sputum exam

89. Which of the following is true of cough variant asthma Large airways are predominantly affected

90. Complications of chronic cough… except (not sure)? Rib fracture

91. 19 year old co-ed, cough 3 weeks, fever, nasal catarrhal, body malaise, had a flu, treated symptomatically, sent home to rest. Symptoms relieved but noted cough 3 days after starting medications Post infectious bronchopneumonia

92. Post-tussive syncope is due to Acute drop in cardiac output while coughing

93. 56 male, cough of 3 months, seen 3 doctors, symptomatic treatment alleviating cough but not to his satisfaction, HTN & IHD, smokes readily, has other current medications: aspirin, captopril, metoprolol, ranitidine, multivitamins. Which of the following medications will you suspect to be causing cough?

Captopril and Metoprolol

94. Cough that gets worse at night is characteristic of: GERD

95. Which of the following describes chronic bronchitis Productive cough for at least 2 years

96. Most common cause of cough is: Upper airway cough syndrome

Pathology 3rd Long Exam

1.  The “global burden of disease” has reported a 50 fold increase in mortality of children under 5 years of age in underdeveloped countries. The major cause of death would be due to:

A.  Congenital disease C. malnutrition and infections

B.  Cardiovascular disease

D. malignant tumors

2.  Recent increases in levels of greenhouse gases are strongly correlated with warming of the earth. The country with the largest emission of CO2 is:

A.  United States C. Russia

B.  China D. Saudi Arabia

3.  An example of a phase 1 xenobiotic metabolizing enxyme that generates DNA- binding metabolic from benzo[a] pyrene from cigarette smoke causing cancer is:

A.  Cytochrome P-450

B.  Biomethylation

C.  Glucouronidation

D.  Conjugation to reduced glutathione

4.  Mortality and morbidity caused by mercury contamination (Minimata disease) is:

A.  Usage of hospital based equipment with mercury

B.  Vaccination using thimesoral as vaccine preservative

C.  Mercury vapors in dental amalgams

D.  Ingestion of organism from contaminate rivers

5.  The mechanism of toxicity in the contamination of Tokyo subways by the organophosphate pesticide SARIN is:

A.  Acetylcholinesterase inhibition

B.  Blocking the re-uptake of acetylcholine

C.  CNS depression

D.  Pulmonary edema causing respiratory failure

6.  The substance in cigarette that makes it addictive is:

A.  Tar

B.  Nitrosamine

C.  Nicotine

D.  Polycyclic aromatic hydrocarbons

7.  The flushing syndrome in an alcoholic drinker is due to genetic variant with inactivity of:

A.  Alcohol dehydrogenase

B.  Acetaldehyde dehydrogenase

C.  Mirosomal ethanol – oxidizing system

D.  Catalase

8.  The use of anabolic steroids by athletes can lead to:

A.  Inhibition of LH and FSH

B.  Testicular hypertrophy

C.  Decrease estrogen

D.  All of the above

9.  The mechanism of action of cocaine is/are:

A.  Blocks re-uptake of Dopamine

B.  Stimulate pre-synaptic norepinephrine release

C.  Inhibits acetylcholinesterase

D.  All of the above

E.  A and B only

10.  The unit of measurement of the dose of radiation that measures the relative biologic effect is/are:

A.  Curie or roentgen

B.  Gray or rads

C.  Sievert or “rem”