Foundations of Clinical Neurophysiology

Neuroscience 1046

Jeffrey R. Balzer, Ph.D.: Course Director

412-648-9779

Tuesday and Thursday, 3:30-5:00 pm

Tuesdays: Room 230, Victoria Bldg.

Thursdays: Room 129, Victoria Bldg.

LectureTopicLecturer

1Course Overview Dr. Crammond

  • What is Clinical Neurophysiology?(08/30/11)

2Functional Neuroanatomy Dr. Thirumala

  • Brain(09/01/11)
  • Brainstem
  • Spinal Cord
  • Cerebrovasculature
  • Cranial Nerves
  • Brachial Plexus/Peripheral Nerves

3NeuropathophysiologyDr. Haybech

  • Injury and Neuronal Responses(09/06/11)
  • Cellular Homeostasis
  • Ischemia
  • Excitatory Amino Acids

4Functional NeurophysiologyDr. Balzer

  • Cerebral Metabolism(09/08/11)
  • Cerebral Blood Flow
  • AVD02
  • Autoregulation
  • CSF Dynamics
  • Blood-Brain Barrier

5Cerebrovascular Anatomy and PhysiologyDr. Balzer

  • Circle of Willis(09/13/11)
  • Anterior Circulation
  • Posterior Circulation
  • Stroke
  • Relationship to Evoked Potentials

6Techniques for Electroencephalographic RecordingDr. Crammond

  • Electrodes(09/15/11)
  • International “Ten-Twenty” System
  • Equipment

7Basic Scalp ElectroencephalographyDr. Thirumala

  • Origin of EEG(09/20/11)
  • Technical Considerations
  • EEG and Anesthesia
  • EEG and Surgical Procedures
  • Computer Processed EEG

8ElectrocorticographyDr. Thirumala

  • Use in Epilepsy Surgery(09/22/11)
  • Technical Aspects of ECoG and Stimulation
  • Awake Craniotomy
  • Anesthetic Considerations

9Intraoperative Evoked PotentialsDr. Balzer

  • Neurophysiologic Basis(09/27/11)
  • Instrumentation
  • Technical Standards

10Somatosensory Evoked PotentialsDr. Crammond

  • Placement of Electrodes(09/29/11)
  • Sensory Tracts
  • Stimulating Electrodes
  • Phase Reversal
  • Clinical Indications for SSEP Recording

11Brainstem Auditory Evoked PotentialsDr. Crammond

  • Placement of Electrodes(10/04/11)
  • Recording Parameters
  • Auditory Pathways/Obligate Waves
  • Clinical Indications for BAEP Recording

12Visual Evoked PotentialsDr. Crammond

  • Stimulating and Recording(10/06/11)
  • Visual Pathways
  • Clinical Indications for VEP Recording
  • Electroretinogram (ERG)

October 11, 2011: NO CLASS

13Motor Evoked PotentialsDr. Balzer

  • Stimulating and Recording(10/13/11)
  • Neurogenic vs. Myogenic
  • Transcranial Electrical Stimulation
  • Motor Pathways
  • Clinical Indications for MEP Recording
  • Anesthetic Considerations

MIDTERM EXAMINATION 10/18/11

15Intraoperative Electromyography (EMG)Dr. Balzer

  • Basic Principles of EMG(10/20/11)
  • Recording EMG
  • Free-Running EMG
  • Stimulus-Evoked EMG
  • Alarm Criteria

16Intraoperative Facial Nerve MonitoringDr. Habeych

  • Monitoring Methods(10/25/11)
  • Electrode Placement
  • Discharge Patterns
  • Hemifacial Spasm
  • Clinical Indications

17Other Cranial Nerve EMGDr. Habeych

  • Extra-ocular Muscle EMG(10/27/11)
  • Trigeminal Nerve EMG
  • Lower Cranial Nerve EMG

18Nerve Root Monitoring in the SpineDr. Balzer

  • Free-Run vs. Stimulus-Evoked EMG(11/01/11)
  • Pedicle Screw EMG
  • Cervical EMG
  • Thoracic EMG
  • Lumbosacral EMG

19Deep Brain StimulationDr. Crammond

  • Anatomy(11/03/11)
  • Physiology
  • Micro-Electrode Recording
  • Guiding the Surgical Placement

20Traumatic Brain InjuryDr. Okonkwo

  • Principles(11/08/11)
  • Pathophysiology
  • ICP
  • Evoked Potentials and Prediction of Outcome

21Anesthesia and Evoked PotentialsDr. Balzer

  • Halogenated Anesthesia(11/10/11)
  • Intravenous Anesthetics
  • Effects on Evoked Potentials
  • Effects on EMG

22Surgical Treatment of EpilepsyDr. Richardson

  • Epilepsy(11/15/11)
  • Conventional Treatment
  • Surgery
  • ECOG and Mapping

23Interventional Radiology, Aneurysms and StrokeDr. Jankowitz

  • Endovascular Treatments(11/17/11)
  • Angiography
  • Aneurysms
  • Stroke

24Cerebral OximetryDr. Balzer

  • Principles(11/22/11)
  • Techniques and Examination
  • Clinical Application

Thanksgiving Break: NO CLASS 11/24/11

25Brain Mapping TechniquesDr. Balzer

  • Phase Reversal(11/29/11)
  • Direct Cortical Stimulation
  • Awake Craniotomy
  • Fourth Ventricle Mapping

26Transcranial DopplerDr. Balzer

  • Cerebrovascular Anatomy(12/01/11)
  • Anatomical Anomalies
  • Techniques and Examination
  • Clinical Application

27Intraoperative Monitoring: Case ReviewsAll Faculty

  • Spine(12/06/11)
  • Vascular
  • Cranial/Tumor
  • Awake Craniotomy
  • Cranial/Microvascular Decompression
  • Brachial Plexus/Peripheral Nerve
  • Deep Brain Stimulation/Microelectrode Recording

28Paper ReviewDr. Balzer

(12/08/11)

December 16, 2011: FINAL PAPER DUE

If you have a disability for which you are or may be requesting an accommodation, you are encouraged to contact both your instructor and Disability Resources and Services, 216 William Pitt Union, 412-648-7890 (412-383-7355 (TTY)), as early as possible in the term. DRS will verify your disability and determine reasonable accommodations for this course.