Clinical Pathology - Terminology

Blood/Erythrocytes/Anemia

The following terms are important for you to understand and be able to define in order to successfully complete this section:

Agranuloctyes

Anemia

Anticoagulants

Band neutrophils

Basophils

Central pallor

Clotting factors

Compensatory polycythemia

Conjugated bilirubin

Deformable

Deoxyhemoglobin

Eosinophils

Erythrocyte

Erythropoiesis

Erythropoietin

Extravascular hemolysis

Fibrin

Fibrinogen

Granulocytes

Haptoglobin

Hematopoiesis

Hemoconcentration

Hemodilution

Hemoglobin

Hemoglobinemia

Hemoglobinuria

Hemolysis

Hemostasis

Homeostasis

Hypoxia

Intravascular hemolysis

Jaundice/Icterus

Leukocyte

Lymphocytes

Monocytes

Macrophages

Metarubricyte

Neutrality

Oxyhemoglobin

pH

Peripheral blood

Phagocytosis

Plasma

Pluripotent stem cell

Polycythemia

Polycythemia rubra vera

Pyknotic

Red Bone Marrow

Regulation

Relative polycythemia

Reticulocyte

Segmented neutrophils

Senescence

Serum

Thrombocyte

Unconjugated bilirubin

Whole blood

Yellow Bone Marrow

In addition, you should be able to…

List and describe the three basic functions of the blood

List the constituents of plasma

Describe the “recipe for an RBC”

Know the difference between the ‘hematocrit’ and PCV, as well as which is more accurate.

List and explain some potential causes of a decreased PCV

List and explain potential causes of an increased PCV

List the erythrocytes in order of maturation from least to most mature and vice versa.

Describe, as an RBC matures from a PPSC, what changes occur in the size and color of the cell and size of the nucleus.

Explain why the color of an RBC changes as it matures

Explain the differences between immature and mature RBCs

Describe the process of normal removal of senescent RBCs

Be able to explain the difference between conjugated and unconjugated bilirubin and the significance of conjugation.

Be able to answer questions on pg. 225 and 229 of your A&P book

Identify morphological changes in RBCs and describe how and why they occur (Poikilocytosis)

Explain what Heinz bodies and Howell Jolly bodies are and why they may be seen on a blood smear

Know the basic types of stain used for hematology studies and how they work

Know the broad ranges for normal numbers of RBCs, WBCs, and PLTs in a microliter of blood

Be able to explain the differences between plasma and serum

Be able to identify, and draw the most common blood parasites