Name:______Date:______
Sergeant System’s Immune System
Defense Team Webquest
The immune system is not located in a specific organ. It’s easiest to think of your body’s immune system as a group of different types of cells and tissues that work together to protect the body. Each cell is designed to perform certain functions, such as killing damaged or infected cells, carrying messages, making antibodies or carrying away debris.
In addition to the above the immune system can identify what cells and substances belong to the body and which do not belong or that are unhealthy.
TASK
Your mission is to research components in the immune system in order to analyze the requirements for an effective defensive immune system. To gather your information refer to the following website:
http://www.sepa.duq.edu/regmed/immune/immune_intro.html
PROCESS
The following parts of the immune system are what you will be responsible for:
· Skin
· Histamine
· Macrophage
· T Cell
· B Cell
· Antibody
· Vaccine
The reading guide that you will find on the following pages will detail the specific research you need to find before you can develop your Employment Profile. Each of the cell parts or organ are the members of your “immune defense system team” that will require a profile.
Applicant #1- The Skin
(Please check off when complete)
o Go to the following website:
http://www.sepa.duq.edu/regmed/immune/immune_intro.html
o Read the information
o Click on the “General Mechanisms” link at the top of the web page and read this information
o Watch the video clip that is on the “
o Answer the questions
1) Hair and mucus are some examples that can help protect your body. In particular, the skin is our first defense against germs! Why is the skin a good defense mechanism for the immune system?
______
2) What would germs do to the body if you didn’t have skin?
______
Applicant #2- Histamine
(Please check off when complete)
o Reread the section titled “ General Mechanisms”
o Answer the following questions
1) Histamines are an important chemical in the body. What is their purpose in the immune system?
______
2) True or False? Circle your response. If it is false, rewrite the statement so it is true.
Histamines are released when the skin blocks germs from entering the immune system.
______
Applicant #3- Macrophages
(Please check off when complete)
o Reread the section titled “ General Mechanisms”
o Draw the image below
1) The macrophage is a swallowing cell, it can engulf things though phagocytosis. Draw what a macrophage looks like when it is eating bacteria.
Applicant #4 – T Cell
(Please check off when complete)
o Reread the section titled “ General Mechanisms”
o Answer the following questions
1) Why do some T Cells remain in the body even after successful getting rid of an intruder?
______
2) Match the description in the left column with the letter of their answers on the right.
Match / Descriptions / Answers1. T cells are a type of white blood cell called_____. / a. Intruder organisms and infected cells
2. This type of T Cell can tell if another cell is infected or not / b. Killer T Cell
3. This type of T Cell carries information and decides when to tell other immune cells to carry out an immune response / c. lymphocytes
4. When a Killer T Cell decides that a cell is unhealthy it can destroy it with______. / d. Specific
5. T Cells can identify individual germs because they are______. / e. Helper T Cell
6. To be able to do their job properly, T cells must learn to only attack______/ f. enzymes
Applicant #5 – B Cell
(Please check off when complete)
o Click the “ B Cells Link at the top of the web page
o Read the information
o Answer the following questions:
1) The B Cell is a special kind of swallowing cell. What do swallowing cells do?
______
2) What is the B cell’s main job as a part of the immune system?
______3) True or False? Circle your response. If false, rewrite the statement so it is true.
The receptor site is a very important part of the B cell- it is called an antibody. This receptor site is a specific binding site on the membrane of the B cell, which means it can bind to many different kinds of harmful particles.
______
Applicant # 6- Antibodies
(Please check off when complete)
o Click the “ B Cells Link at the top of the web page
o Read the information
o Answer the following questions:
1) Circle the True Statement from each pair below:
Antibodies are produced by B cells / OR / Antibodies are produced by T CellsThe antibodies of one B cell can bind many kinds of many particles / OR / The antibodies of one B cell can bind to only one kind of harmful particle
B Cells release antibodies all the time / OR / B cells only release antibodies after becoming plasma B cells.
2) How do antibodies work? Explain.
______
Applicant # 7- Vaccine
(Please check off when complete)
o Click the “ B Cells Link at the top of the web page
o Read the information
o Answer the following questions:
1) We get vaccines all the time. What is a vaccine?
______
2) True or False: If it is incorrect rewrite the explanation:
A vaccine exposes your immune system to a live virus or bacteria so that your B cells will create the specific antibodies. So if you come in contact with them, your B cells will attack so you won’t get sick.
______
Employment Profile
Directions: For each job within the immune system you will refer to your research that you gathered from the website on the previous pages. This will help you to complete an employment profile/ summary of the role that each plays in the immune system. The following need to be a part of your profile; you will need to complete six in total. Antibody has already been done for you.
• Skin
• Histamine
• Macrophage
• T Cell
• B Cell
• Antibody
• Vaccine
Employment Profile Sample:
( You can draw a picture or select an image from the internet)
Name of New Employee: Alexander Antibody
Job Title: Arresting Officer
Job Description: Mr. Antibody is also known as a receptor. He helps a B cell recognize an intruder in the body. Mr. Antibody will stick to this intruder and will hold it “under arrest”. This happens so the intruder cannot move or multiply to make more intruders (pathogens).
(In the job description any specific roles or jobs can be explained for this section)
Name:______
Name:______
Image or drawing
Employment Profile
Name of New Employee: ______
Job Title: ______
Job Description:
______
Conclusion:
Now that you have completed the webquest and profiled your “ Immune Defense System Team” you have gained insight as to how the immune system functions to maintain homeostasis.
Evaluation:
Category / 4 Excellent / 3 Good / 2Average / 1 Needs WorkTeamwork / Partners are supportive and share the responsibility 90%-100% of the time. No conflicts with each other or other classmates / Partners are supportive and share the responsibility 80%-90% of the time. There were a few conflicts working together or with other classmates. / Partners are supportive and share the responsibility 70%-79% of the time.
There were some issues and conflicts working together. / Partners are not supportive and did not share the responsibility. There were many conflicts with each other and or other classmates.
WebQuest
Completeness / Sections 1-5 is 100% complete / Sections 1-5 is 85%- 99% complete / Sections 1-5 is 70%- 84% complete / Sections 1-5 is less than 69% complete.
Answer Accuracy / 90%-100% of the answers are correct. / 80%-89% of the answers are correct. / 70%-79% of the answers are correct. / less than 69% of the answers are correct
Employment Profile Evaluation / Includes all of the following:
New employee’s name
Job title
Job description which includes the location in the immune system.
Main role in the immune system
Special jobs
Picture of employee / Missing no more than 2-3 of the following:
New employee’s name
Job title
Job description which includes the location in the immune system.
Main role in the immune system
Special jobs
Picture of employee / Missing 4-6 of the following:
New employee’s name
Job title
Job description which includes the location in the immune system.
Main role in the immune system
Special jobs
Picture of employee / Missing all of the following:
New employee’s name
Job title
Job description which includes the location in the immune system.
Main role in the immune system
Special jobs
Picture of employee
Source: Adapted from http://sepa.duq.edu/regmed/immune/immune_intro.html. 1/25/16