Table e-2. Visual evoked potentials (VEP) elicited by light emitting diode (LED) goggles or checkerboard pattern reversal (PR) in seven patients with GJA12-related PMLD (cohort A) and seven boys with PMD (cohort B)with age-matched normal values [mean ± SD]11
PatientAge [years]StimEyeVEP wave latencies [ms]
N1Dev [SD]P2Dev [SD]
PMLD patients
A1 4LEDLn. r.
LEDRn. r.
11LEDL140+11220
LEDR144+12226
[74 ± 6][105 ± 8]
A29LEDL104+5130
LEDR108+6132
[74 ± 6][105 ± 8]
13LEDL142+11178
LED R140+11168
[74 ± 6][105 ± 8]
A3 6LEDL122+8170
LEDR152+13172
[74 ± 6][105 ± 8]
A4 9LEDLn. r.
LEDRn. r.
A5 8PRL119151+11
PRR121154+12
[ ± ][105 ± 4]
A6 14LEDLn.r.
Rn.r.
A9 14PRB58125+7
[105 ± 4]
______
PMD patients
B22LEDL134+10174
R128+9168
[74 ± 6][105 ± 8]
3LEDB130+9182
[74 ± 6][105 ± 8]
5LEDL134+10186
R125+9188
[74 ± 6][105 ± 8]
B34LEDL120+8152
R108+6158
[74 ± 6][105 ± 8]
B43LEDB156+14226
[74 ± 6][105 ± 8]
5LEDL135+10220
R140+11220
[74 ± 6][105 ± 8]
B51LEDB144+7190
[80 ± 9][115 ± 10]
5LEDB202+21254
[74 ± 6][105 ± 8]
B6 6LEDL118+7220
R124+8220
[74 ± 6][105 ± 8]
B74LEDL156+14216
R166+15236
[74 ± 6][105 ± 8]
B81LEDL98+2148
R100+2147
[80 ± 9][115 ± 10]
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Stim = stimulation technique for acquisition of VEP; Dev = deviation from normal mean; L = left eye; R = right eye; B = both eyes; n. r. = not recordable
Normative data for LED stimulation as provided in reference #11; for PR stimulation from own data.