XXX Amnon Sonnenberg, M.D.

CURRICULUM VITAE

Amnon Sonnenberg, M.D., M.Sc. June 6, 2004

Home Address: 5431 SW Alta Mira Cicle

Portland, OR 97239

(503) 892-2644

Office Address: Portland VA Medical Center P3-GI

3710 SW US Veterans Hospital Road

Portland, OR 97239

Phone: (503) 220-8262, ext. 56679

FAX: (503) 220-3426

E-mail:

Date of Birth: January 18, 1950

Place of Birth: Haifa, Israel

Citizenship: Israel, Germany, United States

Marital Status: divorced, one son Daniel Sonnenberg, born 1981

Education:

1956-1958 Primary school in Haifa, Israel

1958-1960 Primary school in Aachen, Germany

1960-1968 High school in Aachen

1968-1974 M.D., Medical School, University of Bonn, Germany (Thesis: Comparative study of body plethysmography and spirometry with the helium dilution method in patients with tuberculosis)

1970-1976 M.Sc. in Physics, Department of Physics and Biophysics, University of Bonn, Germany (Thesis: Densitometric and photometric measurements of the association of glutamate dehydrogenase monomers)

Postgraduate Training and Fellowship Appointments:

1974-1975 Research fellowship, Institute of Biochemistry and Biophysics, University of Bonn

1975 Internship, Departments of Medicine and Surgery, University of Bonn

1975-1976 Residency, Department of Medicine, University of Düsseldorf, Germany

1977-1978 Residency, Department of Medicine, Triemli Hospital, Zürich, Switzerland

1978-1979 Research fellowship, Gastroenterology Section, Triemli Hospital, Zürich, Switzerland

1979-1981 Fellowship, Gastroenterology Section, Department of Medicine, University of Düsseldorf, Germany

Faculty Appointments:

1982-1984 Lecturer (Priatdozent) in Internal Medicine, University of Düsseldorf (Docent thesis: Duodenal ulcer and acid secretion)

1985-1986 Lecturer on Medicine, Beth Israel Hosptial, Harvard Medical School

1986 Visiting Professor, The Medical College of Wisconsin, Milwaukee

1987 Assistant Professor of Medicine, Division of Gastroenterology, Department of Medicine, The Medical College of Wisconsin, Milwaukee, WI.

1990 Associate Professor of Medicine, Division of Gastroenterology, Department of Medicine, The Medical College of Wisconsin, Milwaukee, WI.

1990 Secondary Appointment as Associate Professor, Department of Biostatistics and Clinical Epidemiology, The Medical College of Wisconsin, Milwaukee, WI.

1995 Professor of Medicine, Division of Gastroenterology, Department of Medicine, The University of New Mexico, Albuquerque, NM.

2003 Professor of Medicine, Division of Gastroenterology, Department of Medicine, Oregon Health Sciences University.

Hospital and Administrative Appointments:

1986-1995 Staff Physician, Gastroenterology Section, C.J. Zablocki VA Medical Center, Milwaukee, WI.

1986-1995 Associate Staff, Froedtert Memorial Lutheran Hospital, Milwaukee, WI.

1986-1995 Associate Staff, Milwaukee County Medical Complex, Milwaukee, WI.

1987-1995 Staff Physician, Medical Service, C.J. Zablocki VA Medical Center, Milwaukee, WI.

1995-2003 Staff Physician, Medical Service, VA Medical Center, Albuquerque, NM.

2001-2003 Staff Physician, University of New Mexico Health Sciences Center, Albuquerque, NM

2003- Staff Physician, Medical Service, VA Medical Center, Portland, OR.

Specialty Certification:

1981 Board Certificate in Internal Medicine

1982 Board Certificate in Gastroenterology

Licensure:

1975 Medical license, Germany #24.20.06 - Nr. 6385

1982 ECFMG Examination

1983 Visa Qualifying Examination

1987 FLEX Examination

1987 Medical license, Wisconsin #28915

1998 Medical license, New Mexico #98-172

Awards and Honors:

1979 Award of the Swiss Gastroenterological Society for best presentation at the 44th annual meeting

1981 Annual Prize of the Swiss Society for Gastroenterology

1985 Election as member of the European Gastro-Club

1987 Member of Digestive Diseases Epidemiology Working Group of the NIDDK

1988 Walter Zeit Fellow of the Medical College of Wisconsin

2000 Dean's Award of Disctinction in Recognition of Outstanding Faculty Performance University of New Mexico

2001 R.C. Williams Research Award of the University of New Mexico

Editorial Board Memberships:

1997 Member of the Editorial Board of American Journal of Gastroenterology

2000 Member of the Editorial Board of Evidence-Based Gastroenterology

2002 Member of the Editorial Board of Alimentary Pharmacology & Therapeutics

2003 Member of the Editorial Board of Clinical Gastroenterology and Hepatology

Memberships in Professional Societies:

1978 Germany Society of Gastroenterology and Nutrition

1981 Society of Medical Decision Making

1988 American Gastroenterological Association

1995 American Society for Gastrointestinal Endoscopy

1997 American College of Gastroenterology

Professional Experience:

Reviewer: American Journal of Gastroenterology, Cancer Causes & Control, Diabetologia, Digestive Disease and Sciences, Digestion, Gastrointestinal Endoscopy, European Journal of Gastroenterology and Hepatology, Gastroenterology, German Journal of Gastroenterology, Gut, Hepato-Gastroentrology, Hepatology, International Journal of Epidemiology, Journal of the American Medical Association (JAMA), Journal of Clinical Epidemiology, Lancet, New England Journal of Medicine.

Formal course work in epidemiology and biostatistics at the Universities of Zürich and Düsseldorf, training in clinical epidemiology with A.L. Blum (Zürich) and H.J. Jesdinsky (Düsseldorf). Research experience in clinical epidemiology since 1977, with primary interest directed towards the epidemiology of peptic ulcer disease. Since 1984 extension of research activities and funding to other chronic digestive diseases, such as reflux esophagitis, inflammatory bowel disease, and constipation. Long-term objectives are to explore the environmental and socio-economic influences that shape the geographic and temporal trends of chronic digestive diseases.

Research Grants:

Swiss National Foundation, grant no 3.158.077. "Regulation of Gastric Secretion and Motor Function." 1977-1979.

Ministry for Science and Research of Nordrhein-Westfalen, grant no. IV B 5 - FA8681. "Histochemical and Biochemical Examination of the Interaction of Protective and Aggressive Mechanisms in the Stomach." 1979-1981.

Ministry for Science and Research of Nordrhein-Westfalen, grant no. IV B 5 - 9211. "Interaction of Protective and Aggressive Mechanisms at the Gastric Mucosa." 1982-1983.

Heisenberg-Grant, Deutsche Forschungsgemeinschaft, grant no. So 172/1-1. "Epidemiology of Peptic Ulcer Diseases." 1984-1989.

Endoscopic Outcomes and Effectiveness Developmental Research Award of the American Society for Gastrointestinal Endoscopy (ASGE). "Outcome of Endoscopic Retrograde Cholangiography in Biliary Pancreatitis." 1996-1997.

TAP Holdings. "A Medical Decision Analysis of Empirical Therapy in Gastroesophageal Reflux Disease." 1997.

Glaxo Wellcome Educational Grant. "Outcomes and Natural History of Reflux Disease." 1998-1999.

Centers for Disease Control and Prevention. “Economic Implications of Helicobacter pylori Therapy.” 1997-1999.

American Digestive Health Foundation “Models of GERD Treatment and Disease Outcome.” 2000-2001

National Committees:

1994 Participant in the NIH Consensus Development Conference on Helicobacter pylori

1995 Consultant for the Gastrointestinal Drugs Advisory Committee of the Food and Drug Administration

1997 Consultant for the "Education Campaign onHelicobacter pylori "of the Centers for Disease Control and Prevention

2002 Panel Member in the NIH "State-of-the-Science Conference on Endoscopic Retrograde Cholangiopancreatography (ERCP) for Diagnosis and Therapy."

2002 Member in the National Cancer Institue Progress Review Group of Stomach/Esophageal Cancers

Hospital Committees:

1987-1988 Tissue Committee, VA Medical Center, Milwaukee, Wisconsin

1989-1995 Surgical and Invasive Procedures Committee, VA Medical Center, Milwaukee, Wisconsin

1991-1992 Health Services Research Steering Committee, Medical College of Wisconsin

1993 Fact Finding Review Committees, VA Medical Center, Milwaukee, Wisconsin

1992-1995 Health Services Research Team, VA Medical Center, Milwaukee, Wisconsin

1994-1995 Decentralized Medical Management System (DMMS), Implementation Committee, VA Medical Center, Milwaukee, Wisconsin

1988-1999 Search Committee for Associate Chief of Staff for Research and Development, VA Medical Center, Albuquerque, New Mexico

2000-2003 Advisory Committee, Biomedical Research Institute of New Mexico, VA Medical Center, Albuquerque, New Mexico

Teaching at the Medical College of Wisconsin (MCW) and the University of New Mexico (UNM):

  1. Lecturer, Sophomore Class Pharmacology Course (MCW): 1987-1991.
  2. Preceptor, Sophomore Class, Introduction to Physical Diagnosis (MCW): 1989, 1994-1995.
  3. Lecturer, Sophomore Class Pathology Course (MCW): 1987-1995.
  4. Lecturer, Junior Syllabus, Gastrointestinal Disease (MCW): 1990-1995.
  5. Development of Medical Residency Curriculum in Gastroenterology (MCW) 1993-1994
  6. Course director: Didactic Sessions of the Gastroenterology Fellowship Program (MCW): 1991-4
  7. Course director: Gastroenterology Conferences for Medicine Residents (MCW): 1990-1994
  8. Attending Physician, Junior Class, Senior Class: General Medicine Service, VA Medical Center (MCW & UNM): 1988-2002.
  9. Attending Physician, Senior Class: Gastroenterology Consulting Service, VA Medical Center (MCW & UNM): 1988-2002.
  10. Lecturer, Department of Internal Medicine Noon Conferences (MCW & UNM) 1987-2002.
  11. Mentor for Gastroenterology Research Fellows (MCW & UNM): 1987-2001.

Lectures, Workshops, Site Visits:

  1. 25-0H-Vit. D and cyclic AMP in patients with subtotal gastrectomy (Billroth II). 10th Acta Endocrinologica Congress. Amsterdam, August 26-29, 1975. (Co-authors: von Lilienfeld-Toal H, Mackes KG, Ochs H.)
  2. 25-Hydroxyvitamin D3 bei Patienten nach Hemihepatektomie. 82. Tagung der Deutschen Gesellschaft für Innere Medizin. Wiesbaden, April 25-29, 1976. (Co-authors: von Lilienfeld-Toal H, Keck E, Strohmeyer G.)
  3. Plasma renin activity in patients after hemihepatectomy. 10th International Congress of Biochemistry. Hamburg, July 25-31, 1976. (Co-authors: von Lilienfeld-Toal H, Strohmeyer G.)
  4. Stimulation of endogenous cyclic AMP in isolated gastric cells. 11th Acta Endocrinologica Congress, satellite symposium: Evolving Concepts of Hormone Receptors. Würenlingen, June 24-25, 1977. (Co-authors: Hunziker W, Koelz HR, Fischer JA, Blum AL.)
  5. Veränderungen der 25-Hydroxy D3 - Serumkonzentrationen mit zunehmendem Alter. 83. Tagung der Deutschen Gesellschaft für Innere Medizin. Wiesbaden, April 17-21, 1977. (Co-authors: Sonnenberg GE, von Lilienfeld-Toal H.)
  6. Diagnose von Ulkus und Hiatushernie mit Endoskopie und Radiologie. Tagung der Schweizerischen Arbeitsgruppe für gastroenterologische Endoskopie. Olten, May 5-6, 1977. (Co-authors: Hess H, Würsch TG, Walser R, Koelz HR, Pelloni S, Schmid P, Blum AL.)
  7. Epidemiologie der Ulkuskrankheit. Tagung der Schweizerischen Arbeitsgruppe für gastroenterologische Endoskopie. Olten, May 5-6, 1977. (Co-authors: Würsch TG, Walser R, Hess H, Koelz HR, Pelloni S, Stuby K, Schmid P, Blum AL.)
  8. Beziehung zwischen oraler Glucosetoleranz, Insulinempfindlichkeit und Insulin-bindungsfähigkeit der Lymphozytenrezeptoren bei übergewichtigen Erwachsenen-Diabetikern. 12. Kongress der Deutschen Diabetes-Gesellschaft. Homburg/Saar, May 19-21, 1977. (Co-authors: Sonnenberg GE, Bellmann O.)
  9. Die Stimulation des endogenen zyklischen AMP in isolierten, intakten Magenzellen der Ratte. 32. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten. Göttingen, September 22-24, 1977. (Co-authors: Hunziker W, Koelz HR, Fischer JA, Blum AL.)
  10. Stimulation of the endogenous cyclic AMP production in isolated gastric mucosal cells. 9th Meeting of the European Gastro-Club. Erlangen, October 28-29, 1977. (Co-authors: Moran J, Fischer JA, Blum AL.)
  11. Cimetidin in der Behandlung des Ulcus duodeni. Internationales Symposium über Histamin-H2-Rezeptor-Antagonisten. Göttingen, November 10-11, 1977. (Co-authors: Peter P, Gonvers JJ, Pelloni S, Weber K, Strohmeyer G, Hofstetter JR, Blum AL.)
  12. Der Einfluss oraler Kontrazeptiva auf die Demethylierung von Diazepam und Aminopyrin. 84. Tagung der Deutschen Gesellschaft für innere Medizin. Wiesbaden, April 2-6, 1978. (Co-authors: Koelz HR, Herz R, Benes I, Blum AL.)
  13. Determination of gastric mucosal blood flow in man by 14C-aminopyrine: pitfalls and limitations. 12th Annual Meeting of the European Society for Clinical Investigation. Rotterdam, April 20-22, 1978. (Co-authors: Weber K, Mattle W, Benes I, Blum AL.)
  14. Ulcer-like symptoms are specific but not sensitive signs of ulcer disease. 79th Annual Meeting of the American Gastroenterological Association. Las Vegas, May 22-25, 1978. (Co-authors: Blum AL, Hess H, Würsch TG, Walser R, Koelz HR, Pelloni S, Schmid P.)
  15. Hämolytische Aktivität im Magen und Duodenalsaft. Tagung der Schweizerischen Arbeitsgruppe für gastroentrologische Endoskopie. Lausanne, May 20-21, 1978. (Co-authors: Weber KB, Koelz HR, Giger M, Blum AL.)
  16. Prämedikation bei der oberen Fiberendoskopie mit Rachenannästhesie und Psychopharmaka: Bericht über zwei kontrollierte, randomisierte Studien. Tagung der Schweizerischen Arbeitsgruppe für gastroentrologische Endoskopie. Lausanne, May 20-21, 1978. (Co-authors: Giger M, Weber KB, Study K, Mattle W, Blum AL.)
  17. Therapie und Langzeitprophylaxe des Ulcus duodeni mit Cimetidin. Tagung der Schweizerischen Arbeitsgruppe für gastroentrologische Endoskopie. Lausanne, May 20-21, 1978. (Co-authors: Weber KB, Giger M, Mattle W, Stuby K, Blum AL.)
  18. Tetrazyklininduzierte Ulzera im Ösophagus. Tagung der Schweizerischen Arbeitsgruppe für gastroentrologische Endoskopie. Lausanne, May 20-21, 1978. (Co-authors: Brändli H, Braaker J, Giger M, Mattle W, Singeisen M, Güller R, Blum AL.)
  19. Determination of gastric mucosal blood flow in man by 14C-aminopyrine: pitfalls and limitations. 6th World Congress of Gastroenterology. Madrid, June 5-9, 1978. (Co-authors: Benes I, Blum AL.)
  20. Human gastric mucosal secretion and blood flow: action of pentagastrin and isoproterenol. 6th World Congress of Gastroenterology. Madrid, June 5-9, 1978. (Co-authors: Benes I, Blum AL.)
  21. cAMP and cGMP formation in intact cells from rat gastric mucosa. 6th World Congress of Gastroenterology. Madrid, June 5-9, 1978. (Co-authors: Moran J, Fischer JA, Blum AL.)
  22. Telemetrische 24-h-pH-Metrie - Untersuchungen zum Krankheitswert des gastro-oesophagealen Refluxes. 33. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten. Hamburg, September 28-30, 1978. (Co-authors: Lepsien G, Schattenmann G, Blum AL, Siewert JR.)
  23. Die Behandlung der Refluxösophagitis mit Cimetidin. 33. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten. Hamburg, September, 28-30, 1978. (Co-authors: Lepsien G, Berges W, Weber K, Schattenmann G, Wienbeck M, Blum AL, Siewert R.)
  24. Langzeitprophylaxe des Ulcus duodeni mit Cimetidin. 33. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten. Hamburg, September 28-30, 1978. (Co-authors: Kiene K, Peter P, Weber K, Wienbeck M, Blum AL, Strohmeyer G.)
  25. Histaminaufnahme und cAMP-Stimulation isolierter Parietalzellen der Ratte. 43. Jahresversammlung der Schweizerischen Gesellschaft für Gastroenterologie. Montreux: October 5-7, 1978. (Co-authors: Fischer JA, Lewin M, Sachs G, Blum AL.)
  26. Die Behandlung der Refluxösophagitis mit Cimetidin. 43. Jahresversammlung der Schweizerischen Gesellschaft für Gastroenterologie. Montreux: October 5-7, 1978. (Co-authors: Weber KB, Gieger M, Berges W, Wienbeck M, Lepsien G, Siewert R, Blum AL.)
  27. Therapie des Ulcus duodeni mit Cimetidin, Pirenzepin und Placebo: Bericht über eine doppelblinde, randomisierte Studie. 43. Jahresversammlung der Schweizerischen Gesellschaft für Gastroenterologie. Montreux: October 5-7, 1978. (Co-authors: Giger M, Weber KB, Mattle W, Blum AL.)
  28. Parietal cells accumulate aminopyrine, Ca++ , and histamine. 10th Meeting of the European Gastro-Club. Erlangen, October 27-28, 1978. (Co-authors: Fischer JA, Blum AL.)
  29. Prognostic factors in duodenal ulcer disease. 10th Meeting of the European Gastro-Club. Erlangen, October 27-28, 1978. (Co-authors: Blum AL, Gonvers JJ, Giger M.)
  30. Pirenzepin-Behandlung des Ulcus duodeni: Vergleich mit Cimetidin und Placebo. 1. Internationales Pirenzepin-Symposium. Titisee, November 10-11, 1978. (Co-authors: Giger M, Gonvers JJ, Weber KB, Birchler R, Mattle W, Hofstetter JR, Blum AL.)
  31. Duodeno-gastritischer Reflux: Tierexperimentelle und humanmedizinische Untersuchungen. Medizinische Gesellschaft Düsseldorf. Düsseldorf, January 10, 1979.
  32. Therapie des gastro-oesophagealen Refluxes. 11. Internationales Magensymposium. Stuttgart, April 6-7, 1979. (Co-authors: Giger M, Blum AL.)
  33. Quantitative Messung des duodenogastralen Refluxes bei Gesunden und bei Patienten mit benignen peptischen Läsionen des Magens. 85. Tagung der Deutschen Gesellschaft für innere Medizin. Wiesbaden, April 22-26, 1979. (Co-authors: Kern L, Giger M, Benes I, Blum AL.)
  34. Acid secretion of isolated parietal cells: Potassium requirement and the role of Na-K-ATPase. 2nd International Symposium on Hormonal Receptors in Digestive Tract Physiology.