Stanford Child Health Research Institute

Mobilize Stanford discoveries and expertise to launch healthier lives

Transdisciplinary1 Initiatives Program (TIP)

Request for Letters of Intent for Child Health Transdisciplinary Initiatives

Background

The Child Health Research Institute (CHRI) at Stanford University has, as one of its major goals, the creation and fostering of innovative, transdisciplinary child health research and training initiatives between and among the scientific communities at Stanford in the pre-­‐clinical, clinical, and basic sciences in the School of Medicine, engineering and areas related to bioengineering, computer science and technology, the basic and social sciences in H&S, Business, Education, Law, and Earth Sciences. For brevity, child refers to the expectant mother, oocyte, zygote, embryo, fetus, infant, child, and adolescent.

We are seeking proposals for transdisciplinary initiatives in new innovative child health research programs that could best (or only) be performed by faculty from different disciplines, interdisciplinary curricular innovations, seminars and symposia. We encourage faculty from different schools to work together on these initiatives, and strongly promote collaborations between basic and physician scientists. Funding for these grants has been made possible by generous support from the Stanford School of Medicine, the Lucile Packard Children’s Hospital, and gifts raised by the Lucile Packard Foundation for Children’s Health.

Solicitation for Proposals

We are announcing this request for letters of intent (LOI) for transdisciplinary initiatives in child health to all Stanford faculty holding University, Research, or Medical Center line positions. The initiatives will be evaluated as to their quality, novel approaches, potential for stimulating new discoveries, likelihood of being successful, and whether they address the scientific and programmatic goals of CHRI in its broadest sense. The initiative must utilize a multi-­‐PI approach where at least two of these lead investigators are from different disciplines. The combined multi-­‐PI and co-­‐PIs must have faculty from at least two different Schools. The proposal should have potential for obtaining future external support for sustainability, and document how the collaborative effort will be stronger than the sum of two independent projects. We will consider proposals in the range of up to $100,000 a year for two years. Support could be for personnel (undergraduate, graduate, or postdoctoral students, research assistants, or associates, or faculty), supplies, small equipment, travel, or seminar and symposia needs which are an integral part of the proposal.

The LOI should include:

1)  A completed title page using template provided

2)  A one to two-­‐page description (Arial 11 font) of the project goals, the potential impact on child and/or maternal health, and the individuals and disciplines involved

The CHRI Executive Committee will review these LOI. Those groups whose proposals are deemed appropriate will be contacted and asked to develop further their requests. We will accept up to two LOI from one primary PI (if your LOIs are selected for full proposals, only ONE proposal will be accepted from a primary PI). To be eligible, neither the PI nor Co-PIs can have a currently funded TIP award. We are asking that all letters of intent be sent electronically as a Word or PDF document to , no later than October 12, 2016 on or before 5:00PM. You will be notified early November 2016 if your LOI has been selected for a full proposal (see below). You will have nine weeks to write and submit a proposal. Notification of selected proposals is anticipated the week of February 1, 2017, with project start date no later than April 1, 2017.

If you have any questions about the appropriateness of your proposal, or if you need any additional information, please contact Bonnie Whalen at .

The CHRI Executive Committee is looking forward to these and future initiatives that stimulate our child and maternal health faculty to augment their academic activities and advance the state of child health in its broadest terms, by creating novel synergies and leveraging the unique intellectual strengths of Stanford University.

Sincerely,

CHRI Executive Committee

Stanford Child Health Research Institute

Mobilize Stanford discoveries and expertise to launch healthier lives

CHRI TRANSDISCIPLINARY2 INITIATIVES PROGRAM FULL PROPOSAL

i)  Type of Research:

Research must be primarily related to child health. Child refers to the expectant mother, embryo, fetus, infant, child and adolescent. All areas of research are eligible: basic, translational, clinical research, epidemiology/statistics, informatics, health services, or health policy.

ii)  Application

iii)  To be eligible, neither the PI nor co-PIs can have a currently funded TIP award.

The PI (or multi-­‐PI) will submit a digital – based application that includes:

Cover Page (using format provided) Research Team:

For each member (faculty or trainee) of the proposal submit:

•  NIH Biosketch and “Other Support Page”

Research proposal:

The proposal should contain a concise description of the project aims, hypothesis, background, preliminary studies (if available), overall design, methods, and potential pitfalls, and a multi-year budget. For human – based studies there should also be a brief description of sample size and plan for statistical analyses of the results. The proposal should be a maximum 6 pages text, not including references, and no more than 5 additional pages of attachments or appendices. Use Arial 11 point font or larger and place the applicant’s name on every page along with the page number.

iv)  Award

Total award is up to $100,000 per year for two years for a total award of $200,000. Unexpended funds will be returned to the CHRI after the performance period (see No-­‐Cost Extensions below).

Award may be used for:

-  Research personnel

-  PI Salary

-  Computer equipment, software, supplies or ancillary materials or services necessary for the project

-  Travel, symposia, or seminars which are an integral part of the proposal

Award may NOT be used for:

-  Membership dues, journal subscriptions, books

-  Office supplies, ITSS communications

-  Computer equipment, software, or accessories for office or administrative use

-  Any other indirect research costs

v)  No-­‐Cost Extensions

If unforeseen circumstances justify it then the project completion date may be extended beyond the 24 months and funds that have not been fully expended may be requested via a no-­‐cost extension (NCX) of up to 12 months. Requests must be submitted at least thirty (30) days prior to the end date on the award letter. Requests are considered on a case-­‐by-­‐case basis. Not all requests are approved. Only one extension is granted per project.

vi)  Selection Process

Proposals are reviewed by the CHRI Executive Committee. A list of committee members is available upon request.

vii)  Awardee Responsibilities

The PI will take responsibility for the research idea, development methods, supervision and conduct of the study in addition to the following:

-  Be a member of CHRI, keep their Community Academic Profile (CAP) updated, and utilize the “Permit PubMed import” feature.

-  Submit reports in a timely manner, including an annual Progress Report and Financial Report , and a Final Progress and Financial Report within 30 days of the award end date

-  Provide updates in all Progress Reports on funding status from external and/or internal sources

-  Submit progress reports for up to 3 years following the award end date that will include information about grants submitted, publications, employment, and new research funding resulting from this award

-  Present the results of their research when asked

-  Acknowledge the research support of the Stanford Child Health Research Institute at in all publications, abstracts, presentations, press releases, and inventions resulting from this award as follows:

“The project described in this publication was supported by the Stanford Child Health Research Institute.”

CHRI award recipients who have not acknowledged CHRI are not eligible for future awards sponsored by the CHRI.