Appendix 1:

NCR-173 Report (1998 - 2002)

Elected officers for 1998 - 2002

Chairman - Marty Dickman

Secretary - Rusty Rodriguez

Workshop Coordinator -

Rusty Rodriguez - 1998

Lisa Vaillincourt - 1999

Marty Dickman - 2000

Joan Henson - 2001

Regina Redman -2002

Repository Curator - Dave TeBeest

NCRA REP MC

CSREES REP Kitty Cardwell

Workshop meetings:

1998

Meeting Location - Port Townsend, Washington

Meeting Dates - Thursday, 10/8/98 - Sunday, 10, 11, 98

Attendance - 16

1999

Meeting Location - Mammoth Caves National Park, Kentucky

Meeting Dates - Thursday, 11/4/1999 - Sunday, 11/7/1999

Attendance - 20

2000

Meeting Location - Volcano National Park, Hawaii

Meeting Dates - Tuesday, 10/24/00 - Friday, 10/27/00

Attendance - 20

2001

Meeting Location-Bozeman Montana

Meeting Dates - Thursday ,10/4/01 - Sunday, 10/7/01

Attendance -15

2002

Meeting Location-Seattle Washington

Meeting Dates - Friday, 9/6/02 - Saturday, 9/7/02

Attendance -14

NCR-173 Accomplishments for 1998 - 2002

Collaborations Fostered:

The accomplishments resulting from NCR-173 involve research progress from

individual labs, establishment of numerous collaborations, coordination of

research efforts to better define the disease process, unification of

strain designations, use and expansion of the Colletotrichum repository,

training of graduate student, postdoctoral fellows, and technicians.

During the annual workshops, researchers have presented preliminary

and current data in an environment of open discussion and constructive

critique. This has helped the entire group focus research efforts on more

productive areas and to unite our efforts in understanding the basis of

disease in the genus Colletotrichum. In 2002, we expanded the focus to

encompass a number of other fungal genera as well. The workshops have

provided an invaluable experience for undergraduates, graduate students,

post-docs, and technicians to present data where questions are asked and

suggestions made from leaders in the field to aid in their development as

scientists.

One of the major benefits of this workgroup have involved

establishing and maintaining a culture repository so everyone can work with

the same isolates and use standard isolates for comparative purposes. This

standardization has allowed many of us to avoid generating strain-specific

data that could not be compared to other laboratories.

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Several collaborative efforts have been established as a result of

these "workshops" where individual labs are dissecting different aspects of

the disease process. We have coordinated efforts to study penetration,

early signal transduction, colonization, and the communication that results

in the expression of different symbiotic lifestyles (parasitic,

mutualistic, and commensalistic). This has culminated in defining future

directions for the workgroup which include characterizing molecular,

genetic, biochemical, microbiological, and pathological aspects of the

host-fungus interaction to help generate biological agents to control

invasive weeds and protect plants against disease. We expanded our last

workshop to include some field studies to better understand the

distribution host range, and pathology of Colletotrichum species in

habitats impacted by invasive weed species.

Collaborative Manuscripts Written/Published:

Recently, several of the members of NCR-173 have collaborated on a

manuscript describing the use of the Green Fluorescent Protein in studies

of plant-fungal interactions. This manuscript has been published in

"Applied and Environmental Microbiology" (Lorang, J.M., Tuori, R.P. ,

Martinez, J.P., Sawyer. T.L. Redman, R.S., Rollins, J.A.. Wolpert. T.J.,

Johnson, K.B. Rodriguez, R.J., Dickman, M. B., and Ciuffetti, L.M. 2001.

Green fluorescent protein is lighting up fungal biology.Appl. Env.

Microbiol.67:1987-1994), and represents a multi-laboratory effort, and

the spirit of cooperation that NCR-173 is built on. Additional manuscripts

resulting from collaborations established through NCR-173 include: "Fungi

from geothermal soils of Yellowstone National Park" (Redman, R.S.,

Litvintseva, A., Sheehan, K.B., Henson, J.H., and Rodriguez, R.J. 1999.

Applied and Environmental Microbiology. 65:5193-5197); "Field performance

of cucurbit and tomato plants infected with a nonpathogenic mutant of

Colletotrichum magna (teleomorph: Glomerella magna; Jenkins and Winstead)"

(Redman, R.S., Rossinck, M.R., Maher, S., Andrews, Q.C., Schneider, W.L.

and Rodriguez, R.J. 2002. Symbiosis. 32:55-70); and "Plant

thermotolerance conferred by fungal endophyte" (Redman, R.S., Sheehan,

K.B., Stout, R.G., Rodriguez, R.J., and Henson, J.H. 2002. Science.

298:1581). In 1998, several NCR-173 members attended the BARD

International Mycology Conference (Israel) devoted solely to the study of

Colletotrichum as a model system which resulted in the publication of a

collaborative book ("Host specificity, pathology and host pathogen

interactions of Colletotrichum". D. Prusky, S. Freeman, and M. Dickman,

eds. APS press). In October of 2002, a BARD meeting (Tahoe, CA) was

attended by several NCR-173 members to collaboratively discuss the

"Molecular perspectives of fungal biology and pathology: Current status and

future direction" which will result in an MPMI publication. Lastly, it is

important to note that due to the interactions established at the NCR-173

workshops, several collaborations have resulted in the obtainment of

funding (examples: Rodriguez and Freeman - USDA, US/IS BARD; Dickman and

Yarden - BARD; Rodriguez, Freeman, Dickman, and Yarden - US/IS BARD

workshop).

The NCR-173 workshops established in 1991, have been extremely

interactive and well attended. The spirit of scientific cooperation has

never been compromised at these meetings. More importantly, several

laboratories have benefited from these workshops as demonstrated by the

productivity of the NCR-173 group of scientists. As we have grown and

expanded, so have the interests of this diverse group, this necessitating

the proposed change in title of our group.

We believe that NCR-173 has provided an excellent forum for

scientific exchange and advancement. The multiple approaches taken by the

group to understand different aspects of pathogenicity are clearly aimed to

assist the plant pathology community to better understand host -pathogen

interactions.