Office Address Department of Oral Biology

CURRICULUM VITAE

Personal Information:

Name DONG MIN SHIN

Office Address Department of Oral Biology

YonseiUniversityCollege of Dentistry

134 Sinchon-dong, Seodaemoon-ku

Seoul, 120-752, KOREA

Telephone (02) 361-8037 (work) (02) 361-8040 (lab)

Fax number (02) 364-1085

E-Mail Address

Education:

The PosungHigh School 1981

YonseiUniversity, College of Dentistry Dentistry D.D.S. 1987

YonseiUniversity, GraduateSchoolOral Biology M.Sc. 1992

YonseiUniversity, GraduateSchoolOral Biology Ph.D. 1997

Postdoctoral Training:

1. Postdoctoral Researcher, National Heart, Lung, and Blood 1998-1999

Institute, NIH, Laboratory of Cell Signaling;

Bethesda, M.D. (Mentor: Dr. Sue Goo Rhee)

2. Postdoctoral Researcher, University of Texas Southwestern 1999-2002

MedicalCenter at Dallas, Department of Physiology, T.X.

(Mentor: Dr. Shmuel Muallem)

Academic Positions:

1. Instructor Department of Oral biology, College of Dentistry, 1996-1997

(full-time) YonseiUniversity

2. Part time assistant Department of Oral biology, College of Dentistry, 1997-1998

professor YonseiUniversity

3. Associate Department of Oral biology, College of Dentistry, 2002-present

professor YonseiUniversity

Publications:

1.Rosenberg P, Hawkins A, Stiber J, Shelton JM, Hutcheson K, Bassel-Duby R, Shin DM, Yan Z, Williams RS. TRPC3 channels confer cellular memory of recent neuromuscular activity. Proc Natl Acad Sci U S A, 101:9387-9392, 2004

2.Jeong Hee Hong, Syng-Ill Lee, Kyu-Earn Kim, Tai-Soon Yong, Jeong Taeg Seo, Myung Hyun Sohn, Dong Min Shin. German Cockroach Extract Activates Protease Activated Receptor-2 in Human Airway Epithelial Cells.J Allergy Clin Immunol. 113:315-319, 2004

3.Lee HA, Jeong H, Kim EY, Nam MY, Yoo YJ, Seo JT, Shin DM, Ohk SH, Lee SI. Bumetanide, the specific inhibitor of Na+-K+-2Cl- cotransport, inhibits 1alpha,25-dihydroxyvitamin D3-induced osteoclastogenesis in a mouse co-culture system. Exp Physiol. 88:569-574, 2003.

4.Joseph P. Yuan, Kirill Kiselyov, Dong Min Shin, Jin Chen, Nikolay Shcheynikov, Shin H. Kang, Marlin H. Dehoff, Martin K. Schwarz, Peter H. Seeburg, Shmuel Muallem, and Paul F. Worley. Homer binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors. Cell, 114; 777-789, 2003

5.Chong SA, Hong SY, Moon SJ, Park JW, Hong JH, An JM, Lee SI, Shin DM, Seo JT. Partial inhibition of SERCA is responsible for extracellular Ca2+ dependency of AlF4.Am J Physiol Cell Physiol.285:C1142-C1149, 2003

6.Seo SR, Kim YJ, Moon SJ, Sugiya H, Shin DM, Lee SI, Seo JT. Staurosporine-inhibitable protein kinase activity associated with secretory granule membranes isolated from rat submandibular gland cells.Arch Oral Biol. 48;553-558, 2003

7.Dong Min Shin, Marlin Dehoff, Xiang Luo, Shin Hyeok Kang, Jiangchen Tu, Surendra K. Nayak, Elliott M. Ross, Paul F. Worley, and Shmuel Muallem. Homer 2 tunes G protein coupled receptors stimulus intensity by regulating RGS proteins and PLC GAP activities.J. Cell Biol. 162;293-303, 2003

8.Zeng W, Mak DO, Li Q, Shin DM, Foskett JK, Muallem S. A New Mode of Ca2+ Signaling by G Protein-Coupled Receptors. Gating of IP3 Receptor Ca2+ Release Channels by Gbetagamma.Curr Biol. 13:872-876. 2003

9.Kirill Kiselyov, Dong Min Shin, and Shmuel Muallem. Signalling specificity in GPCR-dependent Ca2+ signaling. Cellular Signaling15; 243~253, 2003

10.Dong MinShin and Syng-Ill Lee. Ca2+ Signaling Proteins and Mammalian Sec6/8 Complex.International Journal of Oral Biology27; 91~96, 2002

11.Heeson Chang, Jin-Ill Lee, Dong Min Shin, Seung-Ho Ohk, and Syng-Ill Lee. Effect of Insulin on the Regulation of Na/K/2Cl Cotransporter(NKCC2) in HEK293 Cells. International Journal of Oral Biology27; 129~134, 2002

12.Kim YJ, An JM, Shin DM, Lee SI, Sugiya H, Seo JT. Staurosporine mobilizes Ca2+ from secretory granules by inhibiting protein kinase C in rat submandibular acinar cells. J Dent Res11;788~793, 2002.

13.Joo Young Kim, Kyung Hwan Kim, Jin Ah Lee, Wan Namkung, An-Qiang Sun, Meena Ananthanarayanan, Frederick J. Suchy, Dong Min Shin, Shmuel Muallem, and Min Goo Lee.Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells.Gastroenterology. 122; 1941–1953, 2002

14.Kirill Kiselyov, Dong Min Shin, Xiang Luo, Shigeru B. H. Ko and Shmuel Muallem. Ca2+ signaling in polarized exocrine cells.Adv Exp Med Biol 506:175-183, 2002

15.Kirill Kiselyov, Dong Min Shin, Tomohiro Kurosaki, and Shmuel Muallem.Regulation of Ca2+-release-activated Ca2+current (Icrac) by ryanodine receptors in inositol 1,4,5-trisphosphate-receptor-deficientDT40 cells.Biochem. J. (Research Communication) 360; 17-22, 2001

16.Dong Min Shin, Xiang Luo, Thomas M. Wilkie, Laurence J. Miller, Ammon B. Peck, Michael G. Humphreys-Beher, and Shmuel Muallem. Polarized expression of GPCR and an all-or-nonedischarge of Ca2+ pools at initiation sites of [Ca2+]iwaves in polarized exocrine cells. J Biol. Chem. 276; 44146-44156, 2001

17.Xiao-Song Zhao, Dong Min Shin, Lynne H.Liu, Gary E.Shull and Shmuel Muallem. Plasticity and adaptation of Ca2+ signaling and Ca2+-dependent exocytosis in SERCA2+/- mice. EMBO J. 20; 2680-2689, 2001

Xiao-Song Zhao and Dong Min Shin contributed equally.

18.Dong Min Shin, Xiao-Song Zhao, Xiang Luo, Amal K. Bera, and Shmuel Muallem. Specificity of Ca2+ signaling in polarized cells. Adv. Dent. Res. 14; 12-15, 2000

19.Dong Min Shin, Xiao-Song Zhao, Weizhong Zeng, Marina Mozhayeva, and Shmuel Muallem. The mammalian Sec6/8 complex interacts with Ca2+signaling complexesand regulates their activity. J. Cell Biol.150; 1101–1112, 2000

• This paper was commented importantly as a title of “Polarizing Calcium Waves”, In Brief, inJ. Cell Biol.150, 2000

20.Kirill Kiselyov, Dong Min Shin,Yaming Wang, Isaac N. Pessah, Paul D. Allen, and Shmuel Muallem. Gating of store-operated channels by conformational coupling to ryanodine receptors.Molecular Cell 6, 421–431, 2000

21.Dong Min Shin, Min Goo Lee,Xiang Luo, and Shmuel Muallem. Receptor-specific Ca2+ signaling in polarized cells. J. Korean Med. Sci. 15(Suppl); S46-48, 2000

22.Dong Min Shin, et al.Staurosporine induces intracellular Ca2+ from IP3-insensitive Ca2+ pool.Euro. J. Morphology . 36: 161-164, 1998

23.Dong Min Shin, et al.Mechanism of taste sensation and its disorder. J. Korean Dental Association, 1996

24.Dong Min Shin, et al. Effect of caffiene on carbachol-induced Ca2+ release in rat parotid acini, Yonsei Dental Journal, 1993