CURRICULUM VITAE

Name: Dr Gyöngyi Horváth (Mrs. Tuboly)

Birthdate: November 11, 1955.

Birthplace: Budapest, Hungary

Citizenship: Hungarian

Position: Professor

Institutional affiliation: Faculty of Health Science and Department of Physiology, Albert Szent-Györgyi Medical University, Szeged, Hungary

Marital status: married; Two children: 22 and 26 years old (boys)

Education:

University Medical School of Szeged, Hungary, Medical Doctor (general medicine), 1980.

University Medical School of Szeged, Hungary, Specialist in Anesthesiology, 1985.

Ph.D. 1995.

Habilitation 1998.

Economist (postgraduate course) 2003. (O/GY-18/2003)

D.Sc. 2008 (4757)

Medical translater degree 2008 (15/2008)

Academic appointment

2006- Head of Behavioral-Pharmacological Laboratory, Dept. Physiology, Fac. Medicine, University of Szeged. He is responsible for the physiology education for pharmacy students.

2009- Professor

Membership:

Hungarian Society of Anaesthesiologists

Hungarian Society of Physiologists

European Society of Anaesthesiologists

European Neuroscience Association

Hungarian Society of Pain

Hungarian Society of Neuroscience

Research interest: Neurophysiology, behavioral pharmacology, experimental anesthesiology, drug interaction, endogenous ligands, applied physiology

Current activities: pain medicine; schizophrenia models

Publications:

Original papers: 57 (cumulative impact factor: 113,575)

Congress abstracts: 173 (cumulative impact factor: 52,611)

Book chapter: 1

Citacions: 575, independent:418

Publications between 2000- 2009:

Joo G., Horvath G., Klimscha W., Kekesi G., Dobos I., Szikszay M., Benedek G. The effects of ketamine and its enantiomers on the morphine- or dexmedetomidine-induced antinociception after intrathecal administration in rats. Anesthesiology 93:231-241, 2000.

Impact factor: 3.439

Horvath G. Endomorphin-1 and endomorphin-2. Pharmacology of the selective endogenous µ-opioid receptor agonists. Pharmacol. Ther. 88: 437-463, 2000.

Impact factor: 6.487

Horvath G., Brodacz B., Holzer-Petsche U. Role of calcium channels in the spinal transmission of nociceptive information from the mesentery. Pain 93: 35-41. 2001.

Impact factor: 4.541

Joo G., Horvath G., A ketamin és izomerjeinek szerepe a fájdalomcsillapításban. Aneszt. Int. Ter. 31 9-20. 2001.

Csullog E, JooG., Toth G., Dobos I., Benedek G., and Horvath G. Antinociceptive effect of continuous intrathecal administration of endomorphin-1. Pain 94: 31-38. 2001.

Impact factor: 4.541

Horvath G., Joo G., Dobos I., Klimscha W., Toth G., Benedek G. Synergistic antinociceptive interactions of endomorphin-1 with dexmedetomidine and/or S(+)-ketamine in rats. Anesth. Analg. 93: 1018-1024. 2001.

Impact factor: 2.279

Kekesi G., Joo G., Csullog E., Dobos I., Klimscha W., Toth K., Benedek G., Horvath G.. The antinociceptive effect of intrathecal kynurenic acid and its interaction with endomorphin-1 in rats. Eur. J. Pharmacol. 445:93-96. 2002

Impact factor: 2.342

Fábián G., Bozó B., Szikszay M., Horvath G., Coscia C.J., Szűcs M. Chronic morphine induced changes in mu opioid receptors and G proteins of different subcellular loci in rat brain. JPET 302: 774-778. 2002

Impact factor: 3.991

Horvath G., Brodacz B., Holzer-Petsche U. The haemodynamic interaction of calcium channel blockers with morphine or clonidine at spinal level. N-S Arch. Pharmacol. 366:270-275. 2002

Impact factor: 2.566

Horvath B., Spies C., Horvath G., Kox W.J., Miyamoto S., Barry S., Warden C.H., Bechmann I., Diano S., Heemskerk J., Horvath T.L. Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. Biochem. Pharmacol. 64:369-74. 2002.

Impact factor: 3.542

Kekesi G., Horvath G. A kinurénsav fájdalomcsillapító hatása. Clinical Neuroscience/Ideggyógyászati Szemle. 55:313-322. 2002.

Csüllög E., Horvath G. Az endomorfinok fájdalomcsillapító hatása. Aneszt. Int. Ter. 33:15-28. 2003.

Horvath G., Agil, A., Joo G., Dobos I., Benedek G., Baeyens, J.M. Evaluation of endomorphin-1 on the activity of Na+, K+-ATPase using in vitro and in vivo studies. Eur. J. Pharmacol. 458:291-297, 2003.

Impact factor: 2.352

Dobos. I., Toth K., Kekesi G., Joo G., Csullog E., Klimscha W., Benedek G., Horvath G. Significance of intrathecal catheter location in rats. Anesth. Analg. 96:487-492, 2003.

Impact factor: 2.21

30. Kekesi G., Dobos I., Benedek G. Horvath G. Antinociceptive potency of Sempervivum tectorum L. extract in rats. Phytother. Res. 17:1032-1036, 2003.

Impact factor 0.803

Klimscha W., Ullrich R., Nasel C., Dietrich W., Illievich U.M., Wildling E., Tschernko E., Weidekamm C., Adler L., Heikenwälder G., Horvath G., Sladen R.N. High-dose remifentanil does not impair cerebrovascular carbon dioxide reactivity in healthy male volunteers. Anesthesiology. 99:834-840, 2003.

Impact factor: 3.503

Fábián G., Tombor T., Németh I., Kicsi G.E., Szikszay M., Horvath G., Szűcs M. Upregulation of mu opioid receptors by voluntary morphine administration in drinking water. Acta Biol. Hung. 54:157-166, 2003.

Impact factor: 0.309

Masocha W., Horvath G., Agil A., Ocana M., Del Pozo E., Szikszay M., Baeyens J.M. Role of Na+,K+-ATPase in morphine-induced antinociception. JPET 306:1122-1128, 2003

Impact factor: 4.337

Kekesi G., Dobos I., Benedek G., Horvath G. The antinociceptive potencies and interactions of endogenous ligands during continuous intrathecal administration: adenosine, agmatine, endomorphin-1. Anesth. Analg. 98:420-426, 2004.

Impact factor: 2.180

Nagy E., Toth K., Janositz G., Kovacs G., Feher-Kiss A., Angyan L., Horvath G. Postural control in athletes participating in ironman triathlon. Eur. J. Appl. Physiol. 92:407-413, 2004.

Impact factor: 1.332

Tóth F., Horvath G., Szikszay M., Farkas J.,Tóth G., Borsodi A., Benyhe G. Pharmacological and functional biochemical properties of d-Ala2-d-Nle5-enkephalin-Arg-Phe (DADN). Regul. Pept. 1222:139-146, 2004

Impact factor: 2.531

Kekesi G., Joo G., Csullog E., Peter-Szabo M., Benedek G., Horvath G. Dose-independent antinociceptive interaction of endogenous ligands at the spinal level. Brain Res. 1029:93-102, 2004.

Impact factor: 2.389

Nagy E., Toth K., Janositz G., Kovacs G., Feherne-Kiss A., Horvath G. Az ironman triatlon hatása a testtartás kontrollra. Magyar Sporttudományi Szemle 2004/2-3:43-46, 2004

Barnai M., Laki I., Gyurkovits K., Angyan L., Horvath G. Relationship between breath-hold time and physical performance in patients with cystic fibrosis. Eur. J. Appl. Physiol. 95:172-178, 2005

Impact factor: 1.619

Csoka I, Csanyi E, Zapantis G, Nagy E, Feher-Kiss A, Horvath G, Blazso G, Eros I. In vitro and in vivo percutaneous absorption of topical dosage forms: case studies. Int. J. Pharm. 291:11-19. 2005.

Impact factor: 2.156

Horvath G., Kekesi G., Dobos I., Klimscha W., Benedek G. Long-term changes in the antinociceptive potency of morphine or dexmedetomidine after single treatment. Anesth. Analg. 101:812-818, 2005

Impact factor: 2.452

Horvath G., Kekesi G. Interaction of endogenous ligands mediating antinociception. Brain Res. Rev. 2006 52:69-92, 2006

Impact factor: 5.595

Zapantis G., Csóka I., Csányi E., Horvath G., Erős I. Evaluation of ketamine systemic absorption from topical preparation. Acta Biol. Hung. 57:387-389, 2006

Impact factor: 0.688

Barnai M., Domján A., Varga J., Somfay A., Jeney K.,Sárga N., Verebély B., Horvath Gy. Az állóképesség fejleszthetősége nyolcvan éves korban. Acta Sana 1:26-33, 2006

Koncsek K., Presznerne-Domjan A., Roka E., Sziver E., Horvath G. Az MBT (Masai Barfuss Technologie®) promt hatása a testtartásra. Mozgásterápia 2006/2. 15:16-19. 2006.

Barnai M., Nagy E., Razso K., Domjan A., Horvath G. Az akaratlagos apnoe idő változása za életkor és a fizikai kondíció függvényében. Mozgásterápia 2006/2. 15:10-15. 2006.

Bornemisza E., Presznerne-Domjan A., Barnai M., Nagy E., Horvath G. A súlyviselés és a poszturális kontroll alakulása sacroiliacalis (SI) izületi fájdalom esetén. Acta Sana 1:14-18, 2007.

Peter-Szabo M, Kekesi G, Nagy E, Sziver E, Benedek G, Horvath G. Quantitative characterization of a repeated acute joint inflammation model in rats. Clin. Exp. Pharmacol. Physiol 34:520-526, 2007

Impact factor: 2.038

Nagy E., Feher-Kiss A., Barnai M., Domjan-Preszner A., Angyan L., Horvath G. Postural control in elderly subjects participating in balance training. Eur. J. Appl Physiol. 100:97-104. 2007

Impact factor: 1.752

Horvath G., Kekesi G., Tuboly G., Benedek G. Antinociceptive interactions of triple and quadruple combinations of endogenous ligands at the spinal level. Brain Res. 1155:42-48. 2007.

Impact factor: 2.218

Horvath G., Kekesi G., Nagy E., Benedek G. The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level. Pain 134:277-284. 2008.

Impact factor: 6.030

Janaky M, Palffy A, Horvath G, Tuboly G, Benedek G. Pattern-reversal electroretinograms and visual evoked potentials in retinitis pigmentosa. Doc. Ophthalmol. 117:27-36. 2008.

Impact factor: 1.100

Tuboly G, Mecs L, Benedek G, Horvath G. Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. Clin. Exp. Pharmacol. Physiol 36:400-405. 2009.

Impact factor: 2.196

Tuboly G, Benedek G, Horvath G. Selective disturbance of pain sensitivity after social isolation. Physiol. Behav. 96:18-22. 2009.

Impact factor: 2.806

Tuboly G, Kekesi G, Nagy E, Benedek G, Horvath G. The antinociceptive interaction of anandamide and adenosine at the spinal level. Pharmacol. Biochem. Behav. 91:374-379, 2009

Impact factor: 2.751

Tuboly G, Horvath G. A fájdalomküszöb eltérése szkizofréniás betegekben és állatmodellekben. I. rész. Clinical Neuroscience/Ideggyógyászati Szemle. 62:4-11, 2009.

Tuboly G, Horvath G. A fájdalomküszöb eltérése szkizofréniás betegekben és állatmodellekben. II. rész. Clinical Neuroscience/Ideggyógyászati Szemle. 62:148-153, 2009.

Mecs L, Tuboly G, Nagy E, Benedek G, Horvath G. Peripheral antinociceptive effects of endomorphin-1 and kynurenic acid in the rat inflamed joint model. Anesth Analg. 109:1297-1304, 2009

Impact factor: 2.590

Hartmann P., Szabo A., Eros G., Gurabi D., Horvath G., Nemeth I., Ghyczy M., Boros M. Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats. Eur. J. Pharmacol. 622:58-64 2009.

Impact factor: 2.787

Book chapter:

Szikszay M., Horvath G. and Benedek G. Dramatic increase of fentanyl analgesia and anesthesia by verapamil and clonidine in rats. In: New leads in opioid research (eds) Van Ree, J., Mulder, A.H., Wiegant, V.M. and van Wimersma Greidanus, T.B. Excerpta Medica Amsterdam-New York-Oxford: 1990, p. 86-87.

Toth G.; Fulop, F.; Peter, A.; Fabian, G.; Muranyi, M.; Horvath G.; Szucs, M. New endomorphin analogues using beta-amino acids as proline mimetics in position 2. In: Peptides. Ettore Benedetti and Carlo Pedone (Eds). Editioni Zitno, Napoli, Italy: 2002. p.630-631.