Pre-approved papers for BIOL 801/804, Spring 2004

  1. Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, West SC, Jasin M, Hakem R. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J. 2003 22:6137-47.
  1. Yant, S.R. and Kay, M.A. (2003) Nonhomologous-End-Joining Factors Regulate DNA Repair Fidelity during Sleeping Beauty Element Transposition in Mammalian Cells, Mol. Cell. Biol. 23:8505-8518.
  1. Deans B, Griffin CS, O'Regan P, Jasin M, Thacker J. Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice. Cancer Res. 2003 63:8181-7
  1. Onclercq-Delic R, Calsou P, Delteil C, Salles B, Papadopoulo D, Amor-Gueret M. Aticles, Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing.Nucleic Acids Res. 2003 31:6272-82.
  1. Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol. 2003 23:5706-15.

The following two papers should probably both be presented together:

  1. Porteus MH, Cathomen T, Weitzman MD, Baltimore D. Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks. Mol Cell Biol. 2003, 23:3558-65.
  1. Miller DG, Petek LM, Russell DW. Human gene targeting by adeno-associated virus vectors is enhanced by DNA double-strand breaks. Mol Cell Biol. 2003, 23:3550-7.
  1. Lundin C, Schultz N, Arnaudeau C, Mohindra A, Hansen LT, Helleday T. RAD51 is involved in repair of damage associated with DNA replication in mammalian cells. J Mol Biol. 2003, 328:521-35.
  1. Stark JM, Jasin M. Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks. Mol Cell Biol. 2003, 23:733-43.
  1. Zhong Q, Boyer TG, Chen PL, Lee WH. Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts. Cancer Res. 2002,,62:3966-70
  1. Zhong Q, Chen CF, Chen PL, Lee WH. BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks. J Biol Chem. 2002, 277:28641-7. Epub 2002 May 30.
  1. Pierce AJ, Hu P, Han M, Ellis N, Jasin M. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 2001, 15:3237-42.
  1. Rothkamm K, Kuhne M, Jeggo PA, Lobrich M. Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks. Cancer Res. 2001, 61:3886-93.
  1. Akyuz N, Boehden GS, Susse S, Rimek A, Preuss U, Scheidtmann KH, Wiesmuller L. DNA substrate dependence of p53-mediated regulation of double-strand break repair. Mol Cell Biol. 2002, 22:6306-17.

The following two papers may be presented together:

  1. Pichierri P, Rosselli F, Franchitto A. Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle. Oncogene. 2003,22:1491-500.
  1. Franchitto A, Pichierri P. Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest.

J Cell Biol. 2002 ,157:19-30. Epub 2002 Mar 26

  1. Rassool FV, North PS, Mufti GJ, Hickson ID. Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells. Oncogene. 2003, 22:8749-57
  1. Davalos AR, Campisi J. Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks. J Cell Biol. 2003,162:1197-209.
  1. Sengupta S, Linke SP, Pedeux R, Yang Q, Farnsworth J, Garfield SH, Valerie K, Shay JW, Ellis NA, Wasylyk B, Harris CC. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 2003,22:1210-22.
  1. Pawlowski WP, Golubovskaya IN, Timofejeva L, Meeley RB, Sheridan WF, Cande WZ. Coordination of meiotic recombination, pairing, and synapsis by PHS1. Science. 2004, 303:89-92
  1. Junran Zhang, Henning Willers, Zhihui Feng, Jagadish C. Ghosh, Sang Kim, David T. Weaver, Jay H. Chung, Simon N. Powell, and Fen Xia . Chk2 Phosphorylation of BRCA1 Regulates DNA Double-Strand Break Repair. Mol. Cell. Biol. 2004. 24: 708-718
  1. Andreas Rothfuss and Markus Grompe. Repair Kinetics of Genomic Interstrand DNA Cross-Links: Evidence for DNA Double-Strand Break-Dependent Activation of the Fanconi Anemia/BRCA Pathway. Mol. Cell. Biol. 2004. 24: 123-134.
  1. Jan-Willem F. Theunissen, Mark I. Kaplan, Patricia A. Hunt, Bret R. Williams, David O. Ferguson, Frederick W. Alt, and John H.J. Petrini. Checkpoint Failure and Chromosomal Instability without Lymphomagenesis in Mre11 ATLD1/ATLD1 Mice Molec. Cell 2003 12:1511-1523.