TITLE

Agreement between self-reported and register-based cardiovascular events among Danish breast cancer survivors

JOURNAL NAME

Journal of Cancer Survivorship

AUTHORS

Rikke Langballe1, Esther M John2,3, Kathleen E Malone4, Leslie Bernstein5, Julia A Knight6,7, Charles F Lynch8, Rebecca M Howell9, Roy Shore10, Meghan Woods11, Patrick Concannon12, the WECARE Study Collaborative Group13, Jonine L Bernstein11 and Lene Mellemkjær1

AFFILLIATIONS

1Danish Cancer Society Research Center, Copenhagen, Denmark, 2Cancer Prevention Institute of California, Fremont, CA, USA, 3Department of Health Research and Policy (Epidemiology) and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA, 4Fred Hutchinson Cancer Research Center, Seattle, WA, USA, 5Beckman Research Institute of the City of Hope, Duarte, CA, USA, 6Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada, 7University of Toronto, Dalla Lana School of Public Health, Toronto, Canada, 8University of Iowa, Iowa City, IA, USA, 9Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA, 10New York University School of Medicine, NY, USA 11Memorial Sloan Kettering Cancer Center, New York, NY, USA,12Genetics Institute and Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA,13Membership in the WECARE Study Collaborative Group is provided in the Acknowledgments.

CORRESPONDING AUTHOR

Lene Mellemkjær, Danish Cancer Society Research Center, Strandboulevarden 49, 2100 Copenhagen, Denmark, Phone: +45 3525 7612, Email:

Online Resource, Figure 1. Cardiovascular Conditions

Have you ever been told by a doctor or that you had. . . / No / Not sure/ Don’t know / Yes / If Yes, how old were you when this first occurred? /
Congestive heart failure or cardiomyopathy (weak heart muscle)? / r / r / r / Age
A myocardial infarction (MI, heart attack)? / r / r / r / Age ______
Coronary heart disease? / r / r / r / Age ______
Angina pectoris (chest pains due to lack of oxygen to the heart requiring medication such as nitroglycerin)?
If Yes, do you currently take prescription medications for this?
r No r Yes / r / r / r / Age
Irregular heartbeat or palpitations (arrhythmia) requiring medication, a pacemaker, or follow-up by a doctor?
If Yes, do you currently take prescription medications for this?
r No r Yes / r / r / r / Age
Pericarditis or fluid around the heart? / r / r / r / Age ______
Pericardial constriction (scarring or tightness of the sac around the heart)?
A.  / r / r / r / Age
Stiff or leaking heart valves? / r / r / r / Age ______
Blood clot in head, lung, arm, leg, or pelvis? / r / r / r / Age ______

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Online Resource, Table 1. ICD-8 and ICD-10 Codes Matching Conditions in the Questionnaire

Conditions in questionnaire / ICD-8 / ICD-10
Cardiomyopathy or congestive heart failure / 425, 427.09-427.19, 428 / I42-I43, I50, I11.0, I13.0, I13.2
Myocardial infarction / 410 / I21-I23
Coronary heart disease / 411, 412, 414 / I24-I25
Angina pectoris / 413 / I20
Irregular heartbeat / 427.20-427.97 / I44-I45, I47-I49
Pericarditis or pericardial constriction / 391.09, 393.00, 393.01, 420, 423.01-423.09, 423.00 / I01.0, I09.2, I30, I31.0, I32, I31.1
Valvular diseases / 394-397, 424 / I05-I08, I34-I39
Blood clots in head, lung,
arms, legs or pelvis / 432-435, 444.41-444.90, 450 / I63-I66, I26, I69.3, I69.4, I74.2-174.5

ICD; International Classification of Diseases.

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