Michaela K. Mathews, M.D.

Curriculum Vitae

Michaela Kunz Mathews, M.D.
Assistant Professor, Ophthalmology
University of Maryland School of Medicine

Contact Information:

Business Address: 419 W. Redwood Street, Ste 420

Baltimore, MD 21201

10 S Pine St., MSTF 500-C

Business Phone: 667-214-1232

Fax: 410 328 1178

Email:

Foreign Languages: German (native), French, Spanish, Italian (working knowledge)

Education

8/13/1983 – 1/24/1991 Medical School, University of Vienna, Austria

1/24/1991: M.D. - University of Vienna, Austria

Post Graduate Education and Training

4/1/1991 - 9/30/1994 Internship / Family Medicine Residency

Krankenanstalt des Göttlichen Heilandes

Dornbacher Straße 20-28, 1170 Wien, Austria

10/1/1994 – 5/31/1997 Postdoctoral Fellowship

The Wilmer Eye Institute

Johns Hopkins University School of Medicine

733 N. Broadway, Baltimore, MD 21287

Mentor: Gerard A Lutty, Ph.D., Professor of Ophthalmology

6/24/1997 – 6/23/1998 Preliminary Internal Medicine Residency

Union Memorial Hospital

201 E. University Pkwy., Baltimore, MD 21218

7/ 1/1998 – 8/21/2001 Ophthalmology Residency

UMDNJ, Robert Wood Johnson

3 Cooper Plaza, Suite 510, Camden, NJ 08103

7/ 1/2002 – 6/30/2003 Neuro-ophthalmology Fellowship

Wills Eye Hospital

840 Walnut St. Philadelphia, PA 19107

Mentors: Robert Sergott, MD; Peter Savino, MD

Board Certification

2005, renewed 2015 (expires 2025) Diplomat, American Board of Ophthalmology

Medical Licensures

1991 Active Austria

1998 Inactive New Jersey

2001 Inactive Pennsylvania

2004 Active Maryland

Employment History

Academic Appointments

9/29/04 – 7/31/06 Clinical Assistant Professor

University of Maryland School of Medicine

Dept. of Ophthalmology

8/1/2006 – present Assistant Professor

University of Maryland School of Medicine

Dept. of Ophthalmology

3/1/2009 - present Adjunct appointment: Assistant Professor

University Of Maryland School of Medicine

Dept. of Anatomy and Neurobiology

Other Employment

10/1995 – 05/1996 Research Assistant

Department of Anesthesiology, Johns Hopkins Hospital

600 N. Wolfe St., Baltimore, MD 21287

Supervisor: Quentin Fisher, M.D., Assistant Professor of Anesthesiology

Explanation of gaps in Education and Employment History

8/2001 – 6/2002 Child rearing sabbatical

7/2003 – 9/2004 Family / Maternity leave; Scientific writing

Professional Society Memberships

1994 – present Österreichische Ärztekammer (Austrian Physicians’ Chamber)

1995 – present Association for Research in Vision and Ophthalmology (ARVO)

1999 – present American Academy of Ophthalmology

2005 - present Austrian Scientists in North America (ASCINA)

2007 – present North American NeuroOphthalmology Society (NANOS)

2007 – 2008 Maryland Society of Eye Physicians and Surgeons

2007 – 2008 The Maryland State Medical Society (Med Chi)

2007 – 2008 Baltimore City Medical Society

Honors and Awards

1994 Kurt Gödel scholarship for postgraduate research abroad.

Ministry of Science, Austria

2007 Attending of the year – University of Maryland School of Medicine, Department of Ophthalmology

Clinical Activities

2004 - present Clinical practice at University of Maryland Faculty Physicians, Inc.

2004 - present Attending Physician, Baltimore VA Hospital

2004 - 2009 Ophthalmology Consultant, The Joslin Diabetes Center

University of Maryland Medical Center

500 patient visits / year

2006 - present Director, Ophthalmology Consult Service

University of Maryland Medical Center

2000 patients/year

Clinical Expertise

Board certified Ophthalmologist, Subspecialty fellowship training in Neuroophthalmology.

Expertise in optic neuropathies (congenital, ischemic, compressive, demyelinating, inflammatory, traumatic), ocular motility disorders, disorders of higher visual functions, disorders of ocular innervation, idiopathic intracranial hypertension, systemic diseases, central nervous system disorders, tumors, and other malignancies affecting ocular motility and function,

Scope of Clinical Practice

Primary practice site: University of Maryland Eye Physicians

419 W Redwood St.

Baltimore, MD

Satellite offices: 20, Crossroads Drive

Owings Mills, MD

Waterloo Crossing

Columbia, MD

Other sites: University of MD Medical Center

S Greene St, Baltimore, MD

Baltimore, VA Medical Center

N Greene St., Baltimore, MD

(starting 2017) University of MD Rehabilitation and Orthopedic Institute

Kernan Drive, Baltimore, MD

Total number of patients/week: 40

Number of referrals received/week: 25

Responsibilities with practice: Director, Neuroophthalmology service

Director, Consult Service

Physician Compliance Liaison

EPIC / Portfolio Physician Champion

Portfolio Inpatient Physician Champion

Grand Rounds Committee

Total time spent in clinical duties: 35

Recent Innovations that have influenced practice:

Optical Coherence Tomography: Recent advances in image quality and imaging analysis software allow detailed analysis of optic nerve abnormalities and longitudinal follow-up.

Cancer therapy: New innovative treatment strategies, such as proton beam therapy, have significantly increased individual survival rates and lead to more patients presenting with complex neuroophthalmologic complications of their cancer of treatment side-effects.

Clinical Research

2010 – 2015 Participating Investigator: A double-blind, placebo-controlled study to evaluate new or worsening lens opacification in subjects with non-metastatic prostate cancer receiving Denosumab for bone loss due to Androgen-deprivation therapy.

Protocol 20080560; Sponsor: Amgen, Inc. Time commitment: 2 %

2015 – present Participating Investigator: A Phase 2/3, Double-masked, Placebo-controlled Study with Open-label Extension to Evaluate the Safety and Efficacy of MEDI-551 in Adult Subjects with Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders

Sponsor: Medimmune , Inc. Time commitment: 2%

2015 – present Participating Investigator: Long term, prospective, multinational, parallel-cohort study monitoring safety in patients with MS newly started on fingolimod once daily or treated with another approved disease-modifying therapy. (CFTY720D2403) Sponsor: Medimmune, Inc. Time commitment: 2%

Administrative Service

Institutional Service

2006 - present Physician Compliance Liaison, University Eye Care

2006 - present Director, Ophthalmology Consult Service

2010 - present Portfolio Ambulatory Provider Workgroup / User Group Representative

2012 - present School of Medicine Council (alternative)

2013 Ophthalmology Clinical Competency Committee

2013 Ophthalmology Annual Program Review Committee

2014 - present EPIC / Portfolio Physician Champion Committee

2014 - present Portfolio UMMS Provider Champion Committee

National Service

Ad Hoc Reviewer: Cephalalgia, European Journal of Neurology, European Journal of Ophthalmology, Graefe’s Archive for Clinical and Experimental Ophthalmology, Current Eye Research, PLOS online, Eye.

Local Service

Parent Volunteer: Cromwell Valley Elementary School; Girl Scouts of America, Troop 2455; Boy Scouts of America, Troop 742

Teaching Service

Undergraduate Student Teaching

2014 Mentor, Summer Research Program, 1 student - 10 contact hours/year

2017 Thesis Discussant, University of Maryland Gemstone Honors Research Program

Graduate Student Teaching

2009 - present ICME 520 Introduction to Clinical Medicine Lecturer

University of Maryland School of Medicine

Classroom lecture

160 student hours/year

2006 - present GSUR 531,Ophthalmology Elective Clinical instructor

University of Maryland, School of Medicine

Practice - based individual instruction.

500 student hours / year

2010 - 2013 NPSC 518A Gross Anatomy dissection course Guest Instructor

University of Maryland Dental School

Lab

200 student hours/year

2012 - 2013 HGEN 731: Ophthalmic Genetics Lecturer

University of Maryland School of Medicine

Masters in Genetic counseling program.

25 student hours/year

2013 - 2015 OPTH 589 Ophthalmology Research Mentor

80 student hours / year

2014 - present MSPR 514 Medical Neuroscience Lecturer

University of Maryland School of Medicine

350 student hours/year

2015 - present OPTH 541 Ophthalmology Elective Clinical instructor

500 Student hours/year

2016 - present NEUR 530 Neurology Clerkship Lecturer

Neuroophthalmology lecture for MS3 students

100 Student hours/year

2016 - present FAPH 530 Family Medicine Clerkship Lecturer

Neuroophthalmology lecture for MS3 students

100 Student hours/year

Resident and Fellow teaching

2004 - present Clinical Faculty, Department of Ophthalmology

University of Maryland, School of Medicine

12 residents

Practice - based teaching: Neuroophthalmology, General Ophthalmology, Ophthalmology consults and emergencies; Major and minor surgical procedures.

>250 contact hours/year

2004 - present Neuroophthalmology lecture series for Ophthalmology residents

150 contact hours/year

2006 - present Director and attending physician, Ophthalmology Consult Service

Inpatient, Emergency, Shock-Trauma consult rounds

Minor procedures, Major emergency procedures

1 resident, 2 students

100 contact hours / year

2014 - present Neuroophthalmology lecture for Neurology residents

~20 residents

40 contact hours/year

2016 - present Neuroophthalmology lecture for Medicine residents

~25 residents

25 contact hours/year

Grant Support

CompletedGrants

9/1/09 - 8/31/2015 (no cost extension) PI: 80%

Lipoprotein(A) in vascular diseases of the eye”

National Eye Institute, 1KO8EY016357 - 01A2

Annual Direct Cost: $174,693

Total Direct Cost: $831,115

7/1/1996 – 6/30/1997 PI: 100%

The role of Adenosine in canine retinal microvascular endothelial cell migration and tube formation.”

Knights Templar Eye Foundation

Annual direct cost: $70,000

Publications

Peer-reviewed journal articles

1. MK Mathews, C Merges, DS McLeod, GA Lutty

Vascular endothelial growth factor and vascular permeability changes in human diabetic retinopathy.

Invest. Ophthalmol. Vis. Sci. 1997 Dec; 38 (13): 2729-41.

2. GA Lutty#, MK Mathews, C Merges, DS McLeod

Adenosine stimulates canine retinal microvascular endothelial cell migration and tube formation.

Curr. Eye Res. 1998 Jun; 17(6): 594-607.

3. J Cao, MK Mathews, DS McLeod, C Merges, LM Hjelmeland, GA Lutty

Angiogenic factors in human proliferative sickle cell retinopathy.

Br. J. Ophthalmol. 1999 Jul; 83(7): 838-46.

4. M Kunz-Mathews, DS McLeod, C Merges, J Cao, GA Lutty

Neutrophils and leucocyte adhesion molecules in sickle cell retinopathy.

Br. J. Ophthalmol. 2002; 86:684-690.

5. R. Behbehani, MK Mathews, RC Sergott, PJ Savino

Non-arteritic anterior ischemic optic neuropathy in patients with sleep apnea while being treated with continuous positive airway pressure.

Am. J. Ophthalmol 2005; 139:518-521

6. MK Mathews, L Frohman, HJ Lee, RC Sergott, PJ Savino

Spinal fluid leak after chiropractic manipulation of the cervical spine.

Arch Ophthalmol 2006; 124(2): 283

7. RR Sayegh, KA Madsen, JD Adler, MA Johnson, MK Mathews: Diffuse retinal injury from a non-penetrating TASER dart. Documenta Ophthalmologica 2011; 123 (2): 135-139

8. RR Sayegh, KA Madsen, JD Adler, MA Johnson, MK Mathews: Response to TASER electronic control devices and eye injuries. Documenta Ophthalmologica 2012 Apr;124(2):161-2

9. N Bhatt, R Morales, M Mathews: MRI Findings in Bilateral Post-operative Posterior Ischemic Optic Neuropathy. Open Journal of Ophthalmology. 2013, 3, 51-53. http://dx.doi.org/10.4236/ojoph.2013.33013

10. Mathews M, Albukh T, Duncan K. Early ocular lipid deposition in a mouse model of hyperlipidemia and atherosclerosis. Invest Ophthalmol Vis Sci. 2013;54(15):4104-4104.

11. MK Mathews, Y Guo, P Langenberg, SL Bernstein. Ciliary neurotrophic factor (CNTF) - mediated ganglion cell survival in a rodent model of non-arteritic anterior ischaemic optic neuropathy (NAION). Br J Ophthalmol., 2015;99:133-137 doi:10.1136/bjophthalmol-2014-305969

12. E Couser, SL Bernstein, MK Mathews. Effect of Alzheimer's Disease on Melanopsin Expression in the Lateral Geniculate Nucleus. Invest. Ophthalmol. Vis. Sci. 2015;56(7):5561.

13. MA Malouf, R Levin, MK Mathews. Leber’s Hereditary Optic Neuropathy - Not just a young men’s disease. J Am Geriatr Soc 2016; 64(1): 232. AID JGS13899.

Non-peer-reviewed journal articles

1. MK Mathews, RC Sergott, PJ Savino

Pseudotumor cerebri.

Curr Opin Ophthalmol 2003; 14(6): 364-370.

Reprinted in Contemporary Ophthalmology 2004; 25(3). Review

2. MK Mathews

Nonarteritic anterior ischemic optic neuropathy.

Curr Opin Ophthalmol. 2005; 16(6):341-5. Review

Abstracts and/or Proceedings

1. M Kunz, CA Merges, DS McLeod, GA Lutty

Effects of adenosine on canine retinal capillary endothelial cell migration and vascular cord formation.

IOVS 1995; 36(4): S894.

2. M Kunz, C Merges, DS McLeod, GA Lutty

Vascular endothelial growth factor / vascular permeability factor (VEGF) in diabetic retinopathy.

IOVS 1996; 37(3): S119.

3. MK Mathews, J Cao, C Merges, DS McLeod, GA Lutty

Adhesion molecules, neutrophils and imbalance in the fibrinolytic system in sickle cell retinopathy.

IOVS 1997; 38(4): S1117.

Invited Speeches

1. “Diabetic Eye disease “ The Joslin Diabetes Center; University of Maryland Medical Center. Nov.2006.

2.”What’s New in Diabetic Retinopathy” The Joslin Diabetes Center, University of Maryland Medical Center. Nov. 2007

3. “Nonarteritic Ischemic Optic Neuropathy as a Predictor of Cardiovascular Disease” Austrian Scientists in North America (ASCINA) National Institutes of Health, Bethesda, MD. May, 2009

4. “What's New in Diabetic Retinopathy” The Joslin Diabetes Center, University of Maryland Medical Center. Nov. 2010

5. “Diabetic Retinopathy and other ocular complications of Diabetes Mellitus - Diagnosis and Treatment” Center for Diabetes and Endocrinology, University of Maryland Medical Center. Nov. 2011

6. “Update on Diabetic Retinopathy and related eye diseases” Center for Diabetes and Endocrinology, University of Maryland Medical Center. Nov. 2012

Proffered Communications

1. March 22, 2001: 27th annual meeting of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS),
2. March 30, 2001: The Wills Eye Hospital 54th Annual Conference

Title: Management of Descemet’s rupture from birth trauma with a rigid gas permeable contact lens.

Authors: MK Mathews, BM Schnall, EJ Cohen

3. May 5, 2002: Association for Research in Vision and Ophthalmology (ARVO),

Title: The Super Pinhole test for potential acuity in eyes with cataract.

Authors: MK Mathews, R Rothermel, SM Soll, DB Soll

4. March 14, 2003: The Wills Eye Hospital 55th Annual Conference

Title: Correlation between patient visual acuity and histopathologic parameters of giant cell arteritis. Authors: MK Mathews, RC Eagle Jr, RC Sergott, PJ Savino

5. Feb 12, 2007: North American NeuroOphthalmology Society (NANOS),

Title: Iatrogenic Horner syndrome diagnosed with 0.5% Apraclonidine.

Authors: A Guerami, MK Mathews

6. May 8, 2007: Association for Research in Vision and Ophthalmology (ARVO)

Title: A new transgenic mouse model of neuroprotection in ischemic optic neuropathy.

Authors: MK Mathews, Y Guo, SL Bernstein

7. Feb. 29, 2008: Richard D. Richards Lecture Symposium

University of Maryland School of Medicine

Title: Neuroprotection in ischemic optic neuropathy.

Authors: A Hunter, MK Mathews, SL Bernstein

8. Feb. 29, 2009: NANOS 2009 Annual Meeting, Poster # 51

Title: Severe Vision Loss in Tumors of the Paranasal Sinuses.

Authors: SK Mistr, JC Sailey, MK Mathews

9. May 4, 2009: ARVO Annual Meeting, Poster # 1447

Neuroprotective Effect of Ciliary Neurotrophic Factor (CNTF) in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy.

Authors: MK Mathews, SL Bernstein

10. May 6, 2009: ARVO Annual Meeting, Poster # 4936

Lipoprotein A and C-Reactive Protein in Age-Related Macular Degeneration.

Authors: IA Bhutto, T Baba, C Merges, DS McLeod, MK Mathews, GA Lutty

11. March 9, 2010: NANOS 2010 Annual Meeting, Poster # 2

Title: A Case of Unilateral Optic Neuritis due to Sinus Polyposis.

Authors: LK Law, MK Mathews

12. May 4, 2011: ARVO Annual Meeting, Poster # 4079

Title: Choroidal Changes in the LDL-Receptor-Deficient Mouse Model of Hyperlipidemia and Atherosclerosis.

Author: MK Mathews