DISTRIBUTED BY: Josef Gas.
M A T E R I A L S A F E T Y D A T A S H E E T
PRODUCT IDENTIFIER:NITROUS OXIDE
Product Name(s):NITROUS OXIDEFormula: N2O
Synonym(s): LAUGHING GASChemical Family: OXIDE OF
NITROGEN DINITROGEN
OXIDE
PRODUCT USE(S):Anaesthesia in controlled hospital W.H.M.I.S. Classification
condition. As oxidizer for analyticalClass(es): A, C, D2A
HAZARDOUS INGREDIENTS:
INGREDIENTC.A.S. / P.I.N.CONC. %L.D. 50L.C. 50
PARAMETERSNUMBER(S)VOL./VOL.(Species & Route)(Species & Route)
NITROUS OXIDE10024972/1070APPR. 100 TDLo24mg/kg NOT APPL.
(2 hrs inhl-hum.)
PHYSICAL DATA
PHYSICAL STATE:Gas @ N.T.P.
ODOUR AND APPEARANCE:Colourless and Odourless
ODOUR THRESHOLD:NONE
SPECIFIC GRAVITY (air=1):1.530 (air=1)
VAPOUR PRESSURE:5,074 kPa (736 psig) @ 21.1oC/70 oF
VAPOUR DENSITY:1.812 kg/m3
EVAPORATION RATE:Rapid
BOILING POINT:-88.5oC
FREEZING POINT:-90.8oC
pH:Not Applicable
COEFFICIENT OF WATER/OIL DISTRIBUTION:Not Applicable
SOLUBILITY IN WATER:58.8 cm3 / 100 cm3
% VOLATILES:100
FOR TRANSPORT EMERGENCY CALL COLLECT CANUTEC TEL: 1-613-996-6666
UYI 111-1
FIRE OR EXPLOSION HAZARDS
CONDITIONS OF FLAMMABILITY:NONE. Nitrous Oxide will support and sustain combustion of other materials. Some materials that do not burn in air may ignite in presence of N2O.
MEANS OF EXTINCTION:Cool containers with water spray. Extinguish surrounding fires. N2O will not burn but it will sustain the combustion of surrounding materials.
FLASH POINT:NONE
UPPER FLAMMABLE LIMIT:NONENONELOWER FLAMMABLE LIMIT: NONE
AUTOIGNITION TEMPERATURE:NONE
HAZARDOUS COMBUSTION PRODUCTS:NONE
SENSITIVITY TO MECHANICAL IMPACT:NONE
SENSITIVITY TO STATIC DISCHARGE:NONE
SPECIAL PROCEDURES:Evacuate areas where a leak or a spill is present. Fight surrounding fires as the case may be. Do not use water on the source of leak to avoid ice formation that may obstruct the operation of Safety Relief Devices.
REACTIVITY DATA
CONDITIONS OF CHEMICAL UNSTABILITY:NONE
INCOMPATIBILITY:All combustible, organic material, All reducing agents. Alkali metals.
CONDITIONS OF REACTIVITY:N2O mat react readily with organic compounds.
HAZARDOUS DECOMPOSITION PRODUCTS:NO, NO2.
TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
SKIN (CONTACT):YES
SKIN (ABSORPTION):NO
EYE CONTACT:YES
INHALATION:YES
INGESTION:NO
EFFECTS OF ACUTE EXPOSURE:
Exposure to N2O at 10% may induce analgesia (reduce sensitivity to pain), at higher concentration euphoria, loss of
Coordination and loss of consciousness may occur. At concentrations approaching 100% respiratory arrest may occur.
At concentrations approaching 100% respiratory arrest may occur due to the lack of oxygen, followed by death.
Therapeutic uses of N2O should be supervised by competent medical personnel.
EFFECTS OF CHRONIC EXPOSURE:
Prolonged occupational exposure of abuse has resulted in neurologic effects such as loss of pain, balance, impotence,
Reduction in motor and audiovisual skills. Recovery may occur in months but damages may be permanent. Kidney and
liver disorders have been reported along with fetal malformations and spontaneous abortions.
EXPOSURE LIMITS:T.L.V.\T.W.A. 50 ppm. (25 ppm for operating rooms: OSHA)
IRRITANCY:NONE
SENSITIZATION:NONE
CARCINOGENICITY:NOT AVAILABLE
REPRODUCTIVE TOXICITY:TCLo 20%/8hrs/day 28 days male rat.
TERATOGENICITY:TCLo 5,000 ppm 6 hours inhl-rat (1 – 19 pregn.)
MUTAGENICITY:Chromosome loss in Drosophila after 6 mins @ 99%.
TOXIC SYNERGISTIC PRODUCTS:NONE
UYI 109-3
FIRST AID
EYE:Escaping Gas may harm the unprotected eye if delivered at pressures higher than atmospheric. Obtain medical attention if damages are suspected or present.
INGESTION:Not applicable
INHALATION:Move victim to fresh air if possible. Obtain medical attention. If breathing has stopped , administer C.P.R. If breathing is difficult give oxygen.
SKIN:Contact with cold liquid or vapours may cause frostbite. Treat frostbite if present. Obtain medical attention.
PREVENTIVE MEASURES
PERSONAL PROTECTION
EYE:Safety glasses or goggles to protect from accidental deliveries (leaks) under pressure.
HAND:Not applicable.
FEET:Safety footwear where applicable.
CLOTHING:Long sleeves, trousers recommended.
RESPIRATOR:Not applicable
ENGINEERING CONTROLS:Provide ventilation. Keep oil, grease, and combustible materials away.
SPILL AND LEAK PROCEDURE:
Remove all source of ignition. Clear the area. Spills on combustible surfaces may cause a fire hazard. Try to stop the
leak at source if without risk. Gas will dissipate depending on the site/area ventilation. Verify oxygen concentration prior
to re-entry.
WASTE DISPOSAL:
No wastes may be generated other than empty containers.
HANDLING PROCEDURES & EQUIPMENT:
Use in ventilated areas. Keep away from Oil, Grease, Combustible, Flammable materials.
Use appropriate carts for moving containers. Secure container when in use. Close the container valve when NOT in
use, or when empty. Secure (restrain) during transporation or use.
STORAGE REQUIREMENTS:
Store in well ventilated areas. Keep away from sources of ignition. Store at temperatures below 52oC.
SPECIAL SHIPPING INFORMATION:
Transport upright in well-ventilated vehicle. Do not transport in trunk of enclosed vehicle. Commercial (cylinders)
quantities may NOT be transported in passenger compartments.
T.D.G. SHIPPING NAME:Nitrous OxideT.D.G. CLASSIFICATION CLASS(ES): 2.2 (5.1)
T.D.G. P.I.N. / U.N. :1070
PREPARED BY: JOSEF GAS
TEL:(416) 658-1212
EFFECTIVE DATE:JANUARY 1 2016