1
CURRICULUM VITA
George C. Wood
May 2014
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EDUCATION
University of IllinoisMedicalCenter, Chicago
B.S. in Pharmacy 1965
M.S. in Pharmacy 1968, majorpharmaceutics,
minorphysical chemistry
Ph.D. in Pharmacy 1971, majorpharmaceutics,
minorphysical chemistry
RESEARCH INTERESTS – Development of targeted delivery parenteral dosage forms (nanomedicines) for clinical trials.Educational assessment of student performance.
ACADEMIC APPOINTMENTS
19701974 Associate Professor and Director of Clinical Programs,
University ofArizonaCollege of Pharmacy, Tucson
19741976 Associate Professor University ofTennessee Center for the Health
Sciences, College of Pharmacy, Dept. Molecular and Quantum Biology
1976-1984 Professor, Department of Drug and MaterialToxicology,
University of Tennessee Center for the Health Sciences
1984-1994Professor, Department of Pharmaceutics,
University of Tennessee, Memphis, The HealthSciencesCenter
1994-PresentProfessor, Department of Pharmaceutical Sciences,
University of Tennessee, HealthSciences Center, Memphis TN
ADMINISTRATIVE APPOINTMENTS (University of Tennessee)
1975-1976Acting Chairman, Department of Molecular and QuantumBiology
1976-1981Chairman, Department of Drug and Material Toxicology
1977-1979Director, Midsouth Poison Center
19791981 Executive Director, Southern Poison Center
1992 - 2000 Associate Director, Parenterals Medications Laboratory
2009-2010 Director of Research, Parenteral Medications Laboratories,
University of Tennessee, HealthScienceCenter
2010-2011 Director of Research, Plough Center for Sterile Drug Delivery Systems,
University of Tennessee, HealthScienceCenter
2001-2005Assistant Dean for Education and Assessment, UT College of Pharmacy
2005-2008Associate Dean for Academic Affairs, UT College of Pharmacy
EDUCATIONAL RESPONSIBILITIES
(instructed pharmacy students 1965-2014, instructed graduate students (over 40 years), practioners from the pharmaceutical industry, regulators and scientists over 30 years)
Courses Taught
University of Arizona Professional Courses
Introductory Pathology I and II
Biopharmaceutics and Pharmacokinetics
Clinical Pharmacy Practice - two courses
Research in Pharmaceutics
University of Tennessee Professional Courses
Drug and Material Toxicology 221-Diseases and Drug Therapy I
Drug and Material Toxicology 312-Diseases and Drug Therapy V
Drug and Material Toxicology 321 - Clinical Toxicology
Pharmaceutics 111 - Pharmaceutical Mathematics
Pharmaceutics 123 & 133 - Pharmaceutical Technology I and II
Pharmaceutics 113 - Physical Pharmacy
Pharmacy Administration 111 - Orientation to Pharmacy
Pharmaceutics 340, Research for Pharmacy Students
Oral Pathology - BIDX 307, Dental Therapeutics, Lecturer
Pharmaceutical Sciences- 212 Parenteral Medications
Pharmaceutical Sciences 240- Research for Pharmacy Students
Pharmaceutical Sciences261, Special Problems in
Pharmaceutical Sciences
Graduate Courses Taught
Drug and Material Toxicology 621 - Principles of Toxicology I
Drug and Material Toxicology 622 - Principles of Toxicology II
Pharmaceutics 912 - Physical-chemical Interpretation of Drug ActionSystems III Polyphasic and Disperse Systems
Pharmaceutics 819 - Drug Metabolism
Pharmaceutics 900 - Pharmaceutics Research
Pharmaceutical Sciences 814 - Parenteral Medications
Pharmaceutical Sciences 818 - Physical-Chemical Interpretation of
Polyphasic and Disperse Drug Systems
Pharmaceutical Sciences 900 - Doctoral Dissertation and Research
Pharmaceutical Sciences 840-703 Drug Stability
Pharmaceutical Sciences 840-701 Educational Design & Delivery
Pharmaceutical Sciences 840-702 Educational Assessment
Pharmaceutical Sciences 831 Preformulation/FormulationPrinciples for
Pharmaceutical Dosage Forms
Postdoctoral Courses
Aseptic Processing of Parenteral Medications
3 h lecture and 20 h laboratory instruction per class, 4-5 times annually
(for over 30 years)
Aseptic Compounding for Pharmacy Technicians
10 h laboratory instruction per class
GRADUATE COMMITTEES
University of Arizona
Larry Dick M.S. 1974
James Chubb M.S. 1974
Melvin Simrin M.S. 1975
Robert Gillies M.S. 1975
University of Tennessee
Charles Cruze Ph.D. 1977
June Joyner Ph.D. 1977
Dimitri Papadimitrou Ph.D. 1978
Robert Pennington M.S. 1979
Lee Murdaugh Ph.D. 1981
Cynthia S. Phillips M.S. 1986
Vijay Vashi M.S. 1987
Russell Rackley Ph.D. 1989
Brian Jones M.S. 1989
Roger BarrettM.S. 1991
Vijay Vashi Ph.D. 1991
Troy McCall Ph.D. 1992
Sandeep NemaPh.D. 1992
Gurmukh ChananaPh.D. 1993
Prasad GullapalliPh.D. 1993
Robbie KiddM.S..1997
Gopal KrishnaPh.D.1996
Reba RobertsPh.D. 1999
Napasinee Aksornkoae Ph.D 2002
Yogita Bahl Ph.D. 2002
Yanli Mi Ph.D. 2002
Ramakrishna Nallamothu, Ph. D 2006
Murali Divi Ph.D. 2007
Hari Desu……………………Ph.D 2009
Vinayagam Kannan Ph.D. 2010
Sonia Bedi, Ph.D. 2011
Elizabeth Barker,Ph. D2014
Nivesh Mittel,Ph.D. Candidate
Bivash Mandal,Ph.DCandidate
Rui Zhu, Ph.D. 2013
Jin Xu Ph.D. 2012
Ningning Yang Ph.D. 2012
Bret Koertge, Ph.D. 2014
Suresh Potaraju Ph.D. 2012
Yinqi Zhou Ph.D. 2012
Pavan Balabathula Ph.D.
Wararat Limothal Ph.D.
Postdoctoral Fellows
Meera Iyer, PhD, 1992 - 1994,
Pruthvipaty Katikaneneni, Ph.D., Jan, 1994 - Dec 1994.
Mustaq Fruitiwala Ph.D. Sept 1994-March 1995
Yixin Chen Ph.D. August 1996-1998
Feng Bei, Ph.D. 1995-1999
Patrick Rodrigues, Ph.D. 1999-2000
Himanshu Bhattacharjee Ph.D. 2007-2009
Extramural Support
Dr. Wood has worked as part of the Plough Center for Sterile Drug Delivery on the development of over $10 million for new drug development projects. Additionally, he helped raise $4,500,000 for the development of the new Plough Center for Sterile Drug Delivery. He has worked on Dept of Defense and NIH projects for the development of innovative drug products for the battlefield, various cancers and and high mortality infectious diseases.
Examples of Publications and Patents
R. Nallamothu, G.Wood, M. Divi, H. Desu, F. Horton, L. Thoma "A Tumor Vasculature Targeted Liposome Delivery System for CombretastatinA4:Design, Characterization and In Vitro AAPS PharmSciTech, 2006.
Duntsch C, Divi M K, Jones T, Zhou Q, Krishnamurthy M, Boehm P, Wood G, Sills A, Moore B M, Safety and efficacy of novel cannabinoid chemotherapeutic KM-233 for the treatment of high grade glioma, J Neurooncol 2006, April 77(2): 143-152
Scott, R.C., Want B. Nallamothu, R, Pattillo C, Perez-Liz G, Issekutz A, Dell Valle L, Wood, G.C., Kiani M F,, Targeted delivery of antibody conjugated liposome delivery system for combretastatin A4: design characterization and in vitro evaluation, Biotechnol Bioeng 2007 April 7;7(2):E32
Targeted nanoparticulate drug-delivery systems for treatment of solid tumors: a review
Bhattacharjee, Himanshu; Balabathula, Pavan; Wood, George C.;Therapeutic Delivery (2010), 1(5), 713-734.
Principles of Pharmaceutics in Dosage Form Design. Himanshu Bhattacharjee and George C. Wood; APhA Complete Review for the FPGEE® : Foreign Pharmacy Graduate Equivalency Examination®; Edited by Dick R. Gourley ; ISBN: 1582121435, Publish Date: August 1st 2010
Hongkee Sah, Laura A. Thoma, Hari R. Desu, Edel Sah, and George C. Wood. “Concepts and practices used to develop functional PLGA-based nanoparticulate systems”International Journal of Nanomedicine 2013:8 747-65
Mandal B,Balabathula P,Mittal N,Wood GC,Bhattacharjee H. Development and validation of a spectrofluorimetric method for the determination of erlotinib in spiked human plasma. J Fluoresc.2012 Nov; 22(6):1425-9. doi: 10.1007/s10895-012-1103-8. Epub 2012 Aug 9.
Bivash Mandal, Himanshu Bhattacharjee, Nivesh Mittal, Hongkee Sah, Pavan Balabathula, Laura A. Thoma,George C. Wood. “Core-Shell Type Lipid-Polymer Hybrid Nanoparticles as Drug Delivery Platform. Nanomedicine: Nanotechnology, Biology and Medicine 2013; May 2013, Vol.9, Issue 4, pages 474-491 Top journal in our area of research on nanoparticle drugs.
Nivesh Mittal, Himanshu Bhattacharjee, Bivash Mandal, Pavan Balabathula, Laura Thoma, George C. Wood, “Targeted liposomal drug delivery systems for the treatment of B cell malignancies:, Journal of Drug Targeting, 0, 1-15, Online January 16, 2014
P. Balabathula, D. R. Janagam, N.K. Mittal, B. Mandal, L. Thoma, G. C. Wood, Rapid quantitative evaluation of Amphotericin B in Human Plasma by a validated HPLC Method, Journal of Bioequivalence and Bioavailability, 5, 121-1124, 2013.
Patent 2014, U.S. Provisional Patent No. 61/874,646 for “Liposomes for hematological tumors” Nivesh K. Mittal, George C. Wood, Leonard Lothstein, Pavan Balabathula, Bivesh Mandal
Examples of Abstracts/Presentations
P, Balabathula, S. G Whaley, N. K Mittal, B. Mandal, L. A. Thoma, D.P. Rogers. G. C. Wood, Multifunctional Iron Oxide Nanoparticles for Imaging and Therapy of Systemic Fungal Infections. American Association of Pharmaceutical Scientists, Annual Meeting, San Antonio, TX, 2013.
B Mandal, N. Mittal, P. Balabathula, L. A. Thoma, G. C. Wood. Development and Evaluation of Phospholipid coated Albumin Nanoparticles for the Delivery of Erlotinib in Non-Small Cell Lung Cancer, American Association of Pharmaceutical Scientists, Annual Meeting, San Antonio, TX, 2013.
N. K . Mittal, B. Mandal, P. Balabathula, L. Lothstein, L. A. Thoma, G. C. Wood, Formulation of AD198 Liposomes. American Association of Pharmaceutical Scientists, Annual Meeting, San Antonio, TX, 2013.